The genetic background of circadian and ultradian rhythm patterns of 17-hydroxycorticosteroids: a cross-twin study

in Journal of Endocrinology
Authors:
A. Reinberg
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Y. Touitou
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A. Restoin
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C. Migraine
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F. Levi
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H. Montagner
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ABSTRACT

Circadian and ultradian rhythms in urinary excretion of 17-hydroxycorticosteroids were documented individually during an 8-day span in two pairs of young male twins. Studies were performed once at the age of 6 years for dizygotic twins and twice at the ages of 4·3 and 10·3 years for monozygotic twins. Four different methods were used for time-series analyses: chronograms (raw data), best-fitting curves resulting from cosinor analyses, power spectra and correlations of time-qualified data. Estimates of rhythm parameters (prominent periods, acrophases, etc.) as well as shapes of curves were closer in mono- than in dizygotic twins. Both similarities and small differences in rhythm characteristics of monozygotic twins were detected at both ages considered.

J. Endocr. (1985) 105, 247–253

 

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