Central inhibition of oxytocin release in the rabbit: role of the midbrain

in Journal of Endocrinology
Authors: J. S. Tindal and L. A. Blake
View More View Less
Restricted access

ABSTRACT

Transection of the ventral central grey and surrounding midbrain tegmentum in anaesthetized lactating rabbits caused repeated milk ejections which, on comparison with the effects of i.v. infusions of synthetic oxytocin, synthetic arginine-vasopressin or a mixture of the two, were attributed to continuous release of 1·25–2·5 mu. oxytocin/min, although it is not known whether lesser amounts of vasopressin might also have been released. It is suggested that the ascending midbrain reticular formation, which is known to project rostrally through this region, controls the central inhibition of oxytocin release via the previously described septo-hippocampo-subicular route to the hypothalamus.

J. Endocr. (1986) 109, 405–409

 

      Society for Endocrinology

Sept 2018 onwards Past Year Past 30 Days
Abstract Views 49 26 1
Full Text Views 24 0 0
PDF Downloads 19 0 0