Olfaction plays an important role in sexual maturation and behaviour in the animal kingdom. Evidence that it has the same importance in man is far less convincing and frequently dogged by such anecdotes as the role of pheromones in synchronizing menstrual cyclicity in convents and all-girl schools. Sexual immaturity and defective olfaction do however coexist as an inherited disorder in man (Kallmann's syndrome: Kallmann, Schoenfeld & Barrera, 1944; DeMorsier, 1954; White, Rogol, Brown et al. 1983; Hermanussen & Sippell, 1985; Chaussain, Toublanc, Feingold et al. 1988) and for many years the biological basis of these defects remained enigmatic. Recently, the interrelationship between sexual development and absence of olfaction has been clarified in three mammals: mouse, macaque and man.
A neurobiological basis of hypogonadism and anosmia was first suggested by elegant immunohistochemical studies conducted by Schwanzel-Fukuda & Pfaff (1989a). In the mature mouse, nerve cells that produce
Journal of Endocrinology is committed to supporting researchers in demonstrating the impact of their articles published in the journal.
The two types of article metrics we measure are (i) more traditional full-text views and pdf downloads, and (ii) Altmetric data, which shows the wider impact of articles in a range of non-traditional sources, such as social media.
More information is on the Reasons to publish page.
| Sept 2018 onwards | Past Year | Past 30 Days | |
|---|---|---|---|
| Full Text Views | 2 | 0 | 0 |
| PDF Downloads | 4 | 2 | 0 |
Online ISSN: 1479-6805
Print ISSN: 0022-0795
Strengthening biomedical communities
to advance science and health
CONTACT US
Bioscientifica Ltd | Starling House | 1600 Bristol Parkway North | Bristol BS34 8YU | UK
Bioscientifica Ltd | Registered in England no 3190519
