MAMMOGENESIS AND LACTOGENESIS IN HYPOPHYSECTOMIZED, OVARIECTOMIZED, ADRENALECTOMIZED RATS

in Journal of Endocrinology
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SUMMARY

In the hypophysectomized-ovariectomized-adrenalectomized hooded Norway rat, growth of the mammary ducts can be induced with oestrone + somatotrophin + corticoids; lobule-alveolar development ensues if in addition to the above combination progesterone + prolactin is also administered. On withdrawing these hormones the local injection of prolactin then causes secretion in the underlying mammary gland, but only when corticoids are administered systemically.

 

      Society for Endocrinology

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