EFFECTS OF SALICYLATE ON PLASMA PROTEIN-BOUND IODINE IN THYROXINE-MAINTAINED THYROIDECTOMIZED RATS

in Journal of Endocrinology
Authors:
B. F. GOOD
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B. S. HETZEL
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L. J. OPIT
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SUMMARY

The peripheral effect of salicylate on the plasma protein-bound iodine (PBI) has been studied using thyroidectomized rats. Thyroidectomized rats maintained on adequate thyroxine replacement (6 μg l-thyroxine/100 g body weight) showed striking falls in plasma PBI level following daily administration of salicylate (30 mg/100 g body weight).

 

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