STUDIES ON GRANULATION TISSUE PRODUCTION IN ALLOXAN-DIABETIC RATS

in Journal of Endocrinology
Authors:
S. NAGY
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A. RÉDEI
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S. KARÁDY
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SUMMARY

Alloxan-diabetic rats produce significantly less granulation tissue than normal ones. Locally applied growth hormone (STH), which stimulates granulation tissue in normal rats, lost this ability in diabetic animals. Adrenalectomized alloxan-diabetic rats also fail to respond by increased granulation tissue growth to STH. The stimulation of granulation tissue by STH seems to depend on an adequate supply of insulin.

 

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