THE TIME OF OVULATION IN THE RABBIT FOLLOWING THE INJECTION OF LUTEINIZING HORMONE

in Journal of Endocrinology
Author:
M. J. K. HARPER
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SUMMARY

During a study of the passage of eggs through the uterine tube of the rabbit, information has been obtained about the time which elapses between an intravenous (i.v.) injection of luteinizing hormone (LH) and ovulation. Eighty-four out of 103 mature does injected with 25 i.u. LH, i.v., ovulated, while nineteen failed to ovulate. Laparotomies were performed at various times from 9 hr. 25 min. to 13 hr. after the LH injection and the number of newly ruptured follicles was counted. Autopsies were performed at intervals of 8–64 hr. after the laparotomy and the number of ovulation points was recorded in the eighty-four does that ovulated. The 'percentage ovulation' was calculated by expressing the number of freshly ovulated follicles counted at laparotomy as a percentage of the number of ovulation points counted at autopsy. This showed no ovulation by 9½ hr., 50% ovulation between

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hr. and 88% ovulation by 13 hr. after the injection of LH.

 

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