1. There is a very high correlation between the amounts of urinary androstenol and those of dehydroepiandrosterone, androsterone and aetiocholanolone in women with metastatic breast cancer.
2. In spite of this correlation, which implies a common precursor, tritiated dehydroepiandrosterone or testosterone are not metabolized to androstenol at the periphery (maximum conversion: 0·4% of injected dose) in amounts sufficient to account for the urinary androstenol.
3. As a means of evaluating 'androgen status' androstenol assays do not appear to be more useful than those of the 11-deoxy-17-oxosteroids.
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Online ISSN: 1479-6805
Print ISSN: 0022-0795
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