Arginine-vasotocin (8-arginine-oxytocin, AVT) has been found in the neuro-hypophyses of nearly all vertebrate classes that are lower in the phylogenetic scale than mammals. This hormone has a number of pharmacological properties in common with oxytocin (such as an ability to contract the rat uterus) as well as with vasopressin (ability to increase the blood pressure of anaesthetized rats). AVT has, however, a greater ability than either of these hormones to increase sodium transport (natriferic activity) across the isolated urinary bladder and skin of anurans (see Heller, Pickering, Maetz & Morel, 1961). The present work describes a method for the estimation of AVT in biological materials using the natriferic response of the frog bladder.
The procedure for setting up the preparation of the isolated anuran bladder has been described in detail previously (Bentley, 1958). Frog (Rana esculenta) bladders were tied to the end of a piece of glass tubing, filled with
Journal of Endocrinology is committed to supporting researchers in demonstrating the impact of their articles published in the journal.
The two types of article metrics we measure are (i) more traditional full-text views and pdf downloads, and (ii) Altmetric data, which shows the wider impact of articles in a range of non-traditional sources, such as social media.
More information is on the Reasons to publish page.
| Sept 2018 onwards | Past Year | Past 30 Days | |
|---|---|---|---|
| Full Text Views | 1 | 0 | 0 |
| PDF Downloads | 2 | 0 | 0 |
Online ISSN: 1479-6805
Print ISSN: 0022-0795
Strengthening biomedical communities
to advance science and health
CONTACT US
Bioscientifica Ltd | Starling House | 1600 Bristol Parkway North | Bristol BS34 8YU | UK
Bioscientifica Ltd | Registered in England no 3190519
