Deletion of GFRAL blunts weight lowering effects of FGF21 in female mice

Albertoni M , Shaw PH , Nozaki M , et al. 2002 Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1. Oncogene 21 4212–4219. (https://doi.org/10.1038/sj.onc.1205610)

• PubMed
Albertoni M , Shaw PH , Nozaki M , et al. 2002 Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1. Oncogene 21 4212–4219. (https://doi.org/10.1038/sj.onc.1205610))| false
• Search Google Scholar
• Export Citation

Andersen B , Straarup EM , Heppner KM , et al. 2018 FGF21 decreases body weight without reducing food intake or bone mineral density in high-fat fed obese rhesus macaque monkeys. Int J Obes 42 1151–1160. (https://doi.org/10.1038/s41366-018-0080-7)

• PubMed
Andersen B , Straarup EM , Heppner KM , et al. 2018 FGF21 decreases body weight without reducing food intake or bone mineral density in high-fat fed obese rhesus macaque monkeys. Int J Obes 42 1151–1160. (https://doi.org/10.1038/s41366-018-0080-7))| false
• Search Google Scholar
• Export Citation

Chaffin AT , Larson KR , Huang KP , et al. 2022 FGF21 controls hepatic lipid metabolism via sex-dependent interorgan crosstalk. JCI Insight 7 e155848. (https://doi.org/10.1172/jci.insight.155848)

• PubMed
Chaffin AT , Larson KR , Huang KP , et al. 2022 FGF21 controls hepatic lipid metabolism via sex-dependent interorgan crosstalk. JCI Insight 7 e155848. (https://doi.org/10.1172/jci.insight.155848))| false
• Search Google Scholar
• Export Citation

Chrysovergis K , Wang X , Kosak J , et al. 2014 NAG-1/GDF-15 prevents obesity by increasing thermogenesis, lipolysis and oxidative metabolism. Int J Obes 38 1555–1564. (https://doi.org/10.1038/ijo.2014.27)

• PubMed
Chrysovergis K , Wang X , Kosak J , et al. 2014 NAG-1/GDF-15 prevents obesity by increasing thermogenesis, lipolysis and oxidative metabolism. Int J Obes 38 1555–1564. (https://doi.org/10.1038/ijo.2014.27))| false
• Search Google Scholar
• Export Citation

Coll AP , Chen M , Taskar P , et al. 2020 GDF15 mediates the effects of metformin on body weight and energy balance. Nature 578 444–448. (https://doi.org/10.1038/s41586-019-1911-y)

• PubMed
Coll AP , Chen M , Taskar P , et al. 2020 GDF15 mediates the effects of metformin on body weight and energy balance. Nature 578 444–448. (https://doi.org/10.1038/s41586-019-1911-y))| false
• Search Google Scholar
• Export Citation

Coskun T , Bina HA , Schneider MA , et al. 2008 Fibroblast growth factor 21 corrects obesity in mice. Endocrinology 149 6018–6027. (https://doi.org/10.1210/en.2008-0816)

• PubMed
Coskun T , Bina HA , Schneider MA , et al. 2008 Fibroblast growth factor 21 corrects obesity in mice. Endocrinology 149 6018–6027. (https://doi.org/10.1210/en.2008-0816))| false
• Search Google Scholar
• Export Citation

Dostalova I , Roubicek T , Bartlova M , et al. 2009 Increased serum concentrations of macrophage inhibitory cytokine-1 in patients with obesity and type 2 diabetes mellitus: the influence of very low calorie diet. Eur J Endocrinol 161 397–404. (https://doi.org/10.1530/eje-09-0417)

• PubMed
Dostalova I , Roubicek T , Bartlova M , et al. 2009 Increased serum concentrations of macrophage inhibitory cytokine-1 in patients with obesity and type 2 diabetes mellitus: the influence of very low calorie diet. Eur J Endocrinol 161 397–404. (https://doi.org/10.1530/eje-09-0417))| false
• Search Google Scholar
• Export Citation

Emmerson PJ , Wang F , Du Y , et al. 2017 The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL. Nat Med 23 1215–1219. (https://doi.org/10.1038/nm.4393)

• PubMed
Emmerson PJ , Wang F , Du Y , et al. 2017 The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL. Nat Med 23 1215–1219. (https://doi.org/10.1038/nm.4393))| false
• Search Google Scholar
• Export Citation

Fisher FM , Chui PC , Antonellis PJ , et al. 2010 Obesity is a fibroblast growth factor 21 (FGF21)-resistant state. Diabetes 59 2781–2789. (https://doi.org/10.2337/db10-0193)

• PubMed
Fisher FM , Chui PC , Antonellis PJ , et al. 2010 Obesity is a fibroblast growth factor 21 (FGF21)-resistant state. Diabetes 59 2781–2789. (https://doi.org/10.2337/db10-0193))| false
• Search Google Scholar
• Export Citation

Frikke-Schmidt H , Hultman K , Galaske JW , et al. 2019 GDF15 acts synergistically with liraglutide but is not necessary for the weight loss induced by bariatric surgery in mice. Mol Metab 21 13–21. (https://doi.org/10.1016/j.molmet.2019.01.003)

• PubMed
Frikke-Schmidt H , Hultman K , Galaske JW , et al. 2019 GDF15 acts synergistically with liraglutide but is not necessary for the weight loss induced by bariatric surgery in mice. Mol Metab 21 13–21. (https://doi.org/10.1016/j.molmet.2019.01.003))| false
• Search Google Scholar
• Export Citation

Gerstein HC , Pare G , Hess S , et al. 2017 Growth differentiation factor 15 as a novel biomarker for metformin. Diabetes Care 40 280–283. (https://doi.org/10.2337/dc16-1682)

• PubMed
Gerstein HC , Pare G , Hess S , et al. 2017 Growth differentiation factor 15 as a novel biomarker for metformin. Diabetes Care 40 280–283. (https://doi.org/10.2337/dc16-1682))| false
• Search Google Scholar
• Export Citation

Hale C , Chen MM , Stanislaus S , et al. 2012 Lack of overt FGF21 resistance in two mouse models of obesity and insulin resistance. Endocrinology 153 69–80. (https://doi.org/10.1210/en.2010-1262)

• PubMed
Hale C , Chen MM , Stanislaus S , et al. 2012 Lack of overt FGF21 resistance in two mouse models of obesity and insulin resistance. Endocrinology 153 69–80. (https://doi.org/10.1210/en.2010-1262))| false
• Search Google Scholar
• Export Citation

Hill CM , Laeger T , Dehner M , et al. 2019 FGF21 signals protein status to the brain and adaptively regulates food choice and metabolism. Cell Rep 27 2934–2947.e3. (https://doi.org/10.1016/j.celrep.2019.05.022)

• PubMed
Hill CM , Laeger T , Dehner M , et al. 2019 FGF21 signals protein status to the brain and adaptively regulates food choice and metabolism. Cell Rep 27 2934–2947.e3. (https://doi.org/10.1016/j.celrep.2019.05.022))| false
• Search Google Scholar
• Export Citation

Hill CM , Qualls-Creekmore E , Berthoud HR , et al. 2020 FGF21 and the physiological regulation of macronutrient preference. Endocrinology 161 bqaa019. (https://doi.org/10.1210/endocr/bqaa019)

• PubMed
Hill CM , Qualls-Creekmore E , Berthoud HR , et al. 2020 FGF21 and the physiological regulation of macronutrient preference. Endocrinology 161 bqaa019. (https://doi.org/10.1210/endocr/bqaa019))| false
• Search Google Scholar
• Export Citation

Hsu JY , Crawley S , Chen M , et al. 2017 Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15. Nature 550 255–259. (https://doi.org/10.1038/nature24042)

• PubMed
Hsu JY , Crawley S , Chen M , et al. 2017 Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15. Nature 550 255–259. (https://doi.org/10.1038/nature24042))| false
• Search Google Scholar
• Export Citation

Johnen H , Lin S , Kuffner T , et al. 2007 Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1. Nat Med 13 1333–1340. (https://doi.org/10.1038/nm1677)

• PubMed
Johnen H , Lin S , Kuffner T , et al. 2007 Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1. Nat Med 13 1333–1340. (https://doi.org/10.1038/nm1677))| false
• Search Google Scholar
• Export Citation

Kalinovich AV , De Jong JMA , Cannon B , et al. 2017 UCP1 in adipose tissues: two steps to full browning. Biochimie 134 127–137. (https://doi.org/10.1016/j.biochi.2017.01.007)

• PubMed
Kalinovich AV , De Jong JMA , Cannon B , et al. 2017 UCP1 in adipose tissues: two steps to full browning. Biochimie 134 127–137. (https://doi.org/10.1016/j.biochi.2017.01.007))| false
• Search Google Scholar
• Export Citation

Keinicke H , Sun G , Mentzel CMJ , et al. 2020 FGF21 regulates hepatic metabolic pathways to improve steatosis and inflammation. Endocr Connect 9 755–768. (https://doi.org/10.1530/ec-20-0152)

• PubMed
Keinicke H , Sun G , Mentzel CMJ , et al. 2020 FGF21 regulates hepatic metabolic pathways to improve steatosis and inflammation. Endocr Connect 9 755–768. (https://doi.org/10.1530/ec-20-0152))| false
• Search Google Scholar
• Export Citation

Keipert S , Lutter D , Schroeder BO , et al. 2020 Endogenous FGF21-signaling controls paradoxical obesity resistance of UCP1-deficient mice. Nat Commun 11 624. (https://doi.org/10.1038/s41467-019-14069-2)

• PubMed
Keipert S , Lutter D , Schroeder BO , et al. 2020 Endogenous FGF21-signaling controls paradoxical obesity resistance of UCP1-deficient mice. Nat Commun 11 624. (https://doi.org/10.1038/s41467-019-14069-2))| false
• Search Google Scholar
• Export Citation

Kharitonenkov A , Shiyanova TL , Koester A , et al. 2005 FGF-21 as a novel metabolic regulator. J Clin Invest 115 1627–1635. (https://doi.org/10.1172/jci23606)

• PubMed
Kharitonenkov A , Shiyanova TL , Koester A , et al. 2005 FGF-21 as a novel metabolic regulator. J Clin Invest 115 1627–1635. (https://doi.org/10.1172/jci23606))| false
• Search Google Scholar
• Export Citation

Klein Hazebroek M , Laterveer R , Kutschke M , et al. 2023 Hyperphagia of female UCP1-deficient mice blunts anti-obesity effects of FGF21. Sci Rep 13 10288. (https://doi.org/10.1038/s41598-023-37264-0)

• PubMed
Klein Hazebroek M , Laterveer R , Kutschke M , et al. 2023 Hyperphagia of female UCP1-deficient mice blunts anti-obesity effects of FGF21. Sci Rep 13 10288. (https://doi.org/10.1038/s41598-023-37264-0))| false
• Search Google Scholar
• Export Citation

Kurosu H , Choi M , Ogawa Y , et al. 2007 Tissue-specific expression of βKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21. J Biol Chem 282 26687–26695. (https://doi.org/10.1074/jbc.m704165200)

• PubMed
Kurosu H , Choi M , Ogawa Y , et al. 2007 Tissue-specific expression of βKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21. J Biol Chem 282 26687–26695. (https://doi.org/10.1074/jbc.m704165200))| false
• Search Google Scholar
• Export Citation

Laeger T , Henagan TM , Albarado DC , et al. 2014 FGF21 is an endocrine signal of protein restriction. J Clin Invest 124 3913–3922. (https://doi.org/10.1172/jci74915)

• PubMed
Laeger T , Henagan TM , Albarado DC , et al. 2014 FGF21 is an endocrine signal of protein restriction. J Clin Invest 124 3913–3922. (https://doi.org/10.1172/jci74915))| false
• Search Google Scholar
• Export Citation

Larsson SC & Gill D 2021 Genetic evidence supporting fibroblast growth factor 21 signalling as a pharmacological target for cardiometabolic outcomes and alzheimer's disease. Nutrients 13 1504. (https://doi.org/10.3390/nu13051504)

• PubMed
Larsson SC & Gill D 2021 Genetic evidence supporting fibroblast growth factor 21 signalling as a pharmacological target for cardiometabolic outcomes and alzheimer's disease. Nutrients 13 1504. (https://doi.org/10.3390/nu13051504))| false
• Search Google Scholar
• Export Citation

Macia L , Tsai VW , Nguyen AD , et al. 2012 Macrophage inhibitory cytokine 1 (MIC-1/GDF15) decreases food intake, body weight and improves glucose tolerance in mice on normal & obesogenic diets. PLoS One 7 e34868. (https://doi.org/10.1371/journal.pone.0034868)

• PubMed
Macia L , Tsai VW , Nguyen AD , et al. 2012 Macrophage inhibitory cytokine 1 (MIC-1/GDF15) decreases food intake, body weight and improves glucose tolerance in mice on normal & obesogenic diets. PLoS One 7 e34868. (https://doi.org/10.1371/journal.pone.0034868))| false
• Search Google Scholar
• Export Citation

Makarova EN , Yakovleva TV , Balyibina NY , et al. 2020 Pharmacological effects of fibroblast growth factor 21 are sex-specific in mice with the lethal yellow (A(y)) mutation. Vavilovskii Zhurnal Genet Selektsii 24 200–208. (https://doi.org/10.18699/vj20.40-o)

• PubMed
Makarova EN , Yakovleva TV , Balyibina NY , et al. 2020 Pharmacological effects of fibroblast growth factor 21 are sex-specific in mice with the lethal yellow (A(y)) mutation. Vavilovskii Zhurnal Genet Selektsii 24 200–208. (https://doi.org/10.18699/vj20.40-o))| false
• Search Google Scholar
• Export Citation

Makarova E , Kazantseva A , Dubinina A , et al. 2021 The same metabolic response to FGF21 administration in male and female obese mice is accompanied by sex-specific changes in adipose tissue gene expression. Int J Mol Sci 22 10561. (https://doi.org/10.3390/ijms221910561)

• PubMed
Makarova E , Kazantseva A , Dubinina A , et al. 2021 The same metabolic response to FGF21 administration in male and female obese mice is accompanied by sex-specific changes in adipose tissue gene expression. Int J Mol Sci 22 10561. (https://doi.org/10.3390/ijms221910561))| false
• Search Google Scholar
• Export Citation

Mullican SE , Lin-Schmidt X , Chin CN , et al. 2017 GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates. Nat Med 23 1150–1157. (https://doi.org/10.1038/nm.4392)

• PubMed
Mullican SE , Lin-Schmidt X , Chin CN , et al. 2017 GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates. Nat Med 23 1150–1157. (https://doi.org/10.1038/nm.4392))| false
• Search Google Scholar
• Export Citation

Nedergaard J & Cannon B 2013 UCP1 mRNA does not produce heat. Biochim Biophys Acta 1831 943–949. (https://doi.org/10.1016/j.bbalip.2013.01.009)

• PubMed
Nedergaard J & Cannon B 2013 UCP1 mRNA does not produce heat. Biochim Biophys Acta 1831 943–949. (https://doi.org/10.1016/j.bbalip.2013.01.009))| false
• Search Google Scholar
• Export Citation

Ogawa Y , Kurosu H , Yamamoto M , et al. 2007 βKlotho is required for metabolic activity of fibroblast growth factor 21. Proc Natl Acad Sci U S A 104 7432–7437. (https://doi.org/10.1073/pnas.0701600104)

• PubMed
Ogawa Y , Kurosu H , Yamamoto M , et al. 2007 βKlotho is required for metabolic activity of fibroblast growth factor 21. Proc Natl Acad Sci U S A 104 7432–7437. (https://doi.org/10.1073/pnas.0701600104))| false
• Search Google Scholar
• Export Citation

Patel S , Alvarez-Guaita A , Melvin A , et al. 2019 GDF15 provides an endocrine signal of nutritional stress in mice and humans. Cell Metab 29 707–718.e8. (https://doi.org/10.1016/j.cmet.2018.12.016)

• PubMed
Patel S , Alvarez-Guaita A , Melvin A , et al. 2019 GDF15 provides an endocrine signal of nutritional stress in mice and humans. Cell Metab 29 707–718.e8. (https://doi.org/10.1016/j.cmet.2018.12.016))| false
• Search Google Scholar
• Export Citation

Salminen A , Kaarniranta K & Kauppinen A 2017 Integrated stress response stimulates FGF21 expression: systemic enhancer of longevity. Cell Signal 40 10–21. (https://doi.org/10.1016/j.cellsig.2017.08.009)

• PubMed
Salminen A , Kaarniranta K & Kauppinen A 2017 Integrated stress response stimulates FGF21 expression: systemic enhancer of longevity. Cell Signal 40 10–21. (https://doi.org/10.1016/j.cellsig.2017.08.009))| false
• Search Google Scholar
• Export Citation

Sarruf DA , Thaler JP , Morton GJ , et al. 2010 Fibroblast growth factor 21 action in the brain increases energy expenditure and insulin sensitivity in obese rats. Diabetes 59 1817–1824. (https://doi.org/10.2337/db09-1878)

• PubMed
Sarruf DA , Thaler JP , Morton GJ , et al. 2010 Fibroblast growth factor 21 action in the brain increases energy expenditure and insulin sensitivity in obese rats. Diabetes 59 1817–1824. (https://doi.org/10.2337/db09-1878))| false
• Search Google Scholar
• Export Citation

Søberg S , Sandholt CH , Jespersen NZ , et al. 2017 FGF21 is a sugar-induced hormone associated with sweet intake and preference in humans. Cell Metab 25 1045–1053.e6. (https://doi.org/10.1016/j.cmet.2017.04.009)

• PubMed
Søberg S , Sandholt CH , Jespersen NZ , et al. 2017 FGF21 is a sugar-induced hormone associated with sweet intake and preference in humans. Cell Metab 25 1045–1053.e6. (https://doi.org/10.1016/j.cmet.2017.04.009))| false
• Search Google Scholar
• Export Citation

Talukdar S , Zhou Y , Li D , et al. 2016 A long-acting FGF21 molecule, PF-05231023, decreases body weight and improves lipid profile in non-human primates and type 2 diabetic subjects. Cell Metab 23 427–440. (https://doi.org/10.1016/j.cmet.2016.02.001)

• PubMed
Talukdar S , Zhou Y , Li D , et al. 2016 A long-acting FGF21 molecule, PF-05231023, decreases body weight and improves lipid profile in non-human primates and type 2 diabetic subjects. Cell Metab 23 427–440. (https://doi.org/10.1016/j.cmet.2016.02.001))| false
• Search Google Scholar
• Export Citation

Tsai VW , Macia L , Johnen H , et al. 2013 TGF-b superfamily cytokine MIC-1/GDF15 is a physiological appetite and body weight regulator. PLoS One 8 e55174. (https://doi.org/10.1371/journal.pone.0055174)

• PubMed
Tsai VW , Macia L , Johnen H , et al. 2013 TGF-b superfamily cytokine MIC-1/GDF15 is a physiological appetite and body weight regulator. PLoS One 8 e55174. (https://doi.org/10.1371/journal.pone.0055174))| false
• Search Google Scholar
• Export Citation

Tsai VW , Manandhar R , Jorgensen SB , et al. 2014 The anorectic actions of the TGFβ cytokine MIC-1/GDF15 require an intact brainstem area postrema and nucleus of the solitary tract. PLoS One 9 e100370. (https://doi.org/10.1371/journal.pone.0100370)

• PubMed
Tsai VW , Manandhar R , Jorgensen SB , et al. 2014 The anorectic actions of the TGFβ cytokine MIC-1/GDF15 require an intact brainstem area postrema and nucleus of the solitary tract. PLoS One 9 e100370. (https://doi.org/10.1371/journal.pone.0100370))| false
• Search Google Scholar
• Export Citation

Tsai VW , Macia L , Feinle-Bisset C , et al. 2015 Serum levels of human MIC-1/GDF15 vary in a diurnal pattern, do not display a profile suggestive of a satiety factor and are related to BMI. PLoS One 10 e0133362. (https://doi.org/10.1371/journal.pone.0133362)

• PubMed
Tsai VW , Macia L , Feinle-Bisset C , et al. 2015 Serum levels of human MIC-1/GDF15 vary in a diurnal pattern, do not display a profile suggestive of a satiety factor and are related to BMI. PLoS One 10 e0133362. (https://doi.org/10.1371/journal.pone.0133362))| false
• Search Google Scholar
• Export Citation

Véniant M , Sivits G , Helmering J , et al. 2015 Pharmacologic effects of FGF21 are independent of the “browning” of white adipose tissue. Cell Metab 21 731–738. (https://doi.org/10.1016/j.cmet.2015.04.019)

• PubMed
Véniant M , Sivits G , Helmering J , et al. 2015 Pharmacologic effects of FGF21 are independent of the “browning” of white adipose tissue. Cell Metab 21 731–738. (https://doi.org/10.1016/j.cmet.2015.04.019))| false
• Search Google Scholar
• Export Citation

Wang D , Townsend LK , Desormeaux GJ , et al. 2023 GDF15 promotes weight loss by enhancing energy expenditure in muscle. Nature 619 143–150. (https://doi.org/10.1038/s41586-023-06249-4)

• PubMed
Wang D , Townsend LK , Desormeaux GJ , et al. 2023 GDF15 promotes weight loss by enhancing energy expenditure in muscle. Nature 619 143–150. (https://doi.org/10.1038/s41586-023-06249-4))| false
• Search Google Scholar
• Export Citation

Xiong Y , Walker K , Min X , et al. 2017 Long-acting MIC-1/GDF15 molecules to treat obesity: evidence from mice to monkeys. Sci Transl Med 9 eaan8732. (https://doi.org/10.1126/scitranslmed.aan8732)

• PubMed
Xiong Y , Walker K , Min X , et al. 2017 Long-acting MIC-1/GDF15 molecules to treat obesity: evidence from mice to monkeys. Sci Transl Med 9 eaan8732. (https://doi.org/10.1126/scitranslmed.aan8732))| false
• Search Google Scholar
• Export Citation

Xu J , Lloyd DJ , Hale C , et al. 2009 Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice. Diabetes 58 250–259. (https://doi.org/10.2337/db08-0392)

• PubMed
Xu J , Lloyd DJ , Hale C , et al. 2009 Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice. Diabetes 58 250–259. (https://doi.org/10.2337/db08-0392))| false
• Search Google Scholar
• Export Citation

Yang L , Chang CC , Sun Z , et al. 2017 GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand. Nat Med 23 1158–1166. (https://doi.org/10.1038/nm.4394)

• PubMed
Yang L , Chang CC , Sun Z , et al. 2017 GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand. Nat Med 23 1158–1166. (https://doi.org/10.1038/nm.4394))| false
• Search Google Scholar
• Export Citation

Zhang M , Sun W , Qian J , et al. 2018 Fasting exacerbates hepatic growth differentiation factor 15 to promote fatty acid β-oxidation and ketogenesis via activating XBP1 signaling in liver. Redox Biol 16 87–96. (https://doi.org/10.1016/j.redox.2018.01.013)

• PubMed
Zhang M , Sun W , Qian J , et al. 2018 Fasting exacerbates hepatic growth differentiation factor 15 to promote fatty acid β-oxidation and ketogenesis via activating XBP1 signaling in liver. Redox Biol 16 87–96. (https://doi.org/10.1016/j.redox.2018.01.013))| false
• Search Google Scholar
• Export Citation

Zouhar P , Janovska P , Stanic S , et al. 2021 A pyrexic effect of FGF21 independent of energy expenditure and UCP1. Mol Metabol 53 101324. (https://doi.org/10.1016/j.molmet.2021.101324)

• PubMed
Zouhar P , Janovska P , Stanic S , et al. 2021 A pyrexic effect of FGF21 independent of energy expenditure and UCP1. Mol Metabol 53 101324. (https://doi.org/10.1016/j.molmet.2021.101324))| false
• Search Google Scholar
• Export Citation