The nasal glands of the domestic duck secrete a sodium chloride solution after the administration of solutions hypertonic to the plasma. The response is abolished by adrenalectomy and restored on treatment of adrenalectomized animals with corticosteroids (Phillips, Holmes & Butler, 1961). Although the secretory activity is dependent on the presence of circulating hormones of the cortisol-corticosterone type, the concentration of these hormones in plasma is not affected by stimuli that result in secretion (Donaldson & Holmes, 1965; Macchi, Phillips, Brown & Yasuna, 1965). In the following report, the tissue distribution of corticosteroids and their metabolites was examined in ducklings in order to clarify the role of the adrenal cortex in the control of the nasal glands.
Male ducklings (Anas platyrhynchos) of the Peking white or Aylesbury strain were used. The treatment of animals and the operative procedures were as described previously (Phillips & Bellamy, 1962). To determine inulin space, inulin
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