HIRSUTISM, VIRILISM AND APPARENT VIRILISM AND THEIR GONADAL RELATIONSHIP

in Journal of Endocrinology
Author:
F. T. G. PRUNTY
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CONTENTS

Part I

Introduction

Virilizing changes and genetic abnormalities

Testicular feminization

Virilizing tumours of the ovary (clinical and pathological features)

Clinical effects of removal of ovarian tumours

Steroid metabolism and ovarian tumours

Summary of the diagnostic features of ovarian tumours

References (for Part I)

Part II

The Stein-Leventhal syndrome

Clinical features

Treatment

The pathological features of the polycystic ovary

Hormonal abnormalities

The adrenocortical contribution to the Stein-Leventhal syndrome

Stimulation with gonadotrophins

The effects of wedge resection

The effects of clomiphene

Theories of origin of the Stein-Leventhal syndrome

Diagnosis of the Stein-Leventhal syndrome

The pathological importance of the theca cell-interstitial cell-hilar cell system

Simple or idiopathic hirsutism

References (for Part II)

INTRODUCTION

Virilism is often caused by a well-definable endocrine abnormality of the adrenal cortex or ovaries. The changes include hirsutism of face, abdomen, chest and increase of hair on the arms and legs (Ferriman & Gallwey, 1961; Shah & Mahajan,

 

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