The results of treatment of three oligospermic men for periods of up to 12 months with human pituitary gonadotrophin alone and in combination with human chorionic gonadotrophin (Pregnyl) is described. The addition of exogenous gonadotrophin resulted in a small but significant stimulation of spermatogenesis which was confirmed by quantitative histological assessment of testicular biopsy specimens taken before, during and after treatment. The time taken for a response in the ejaculate appears to be dependent on the initial histological appearance of the testis, in particular the stage of germinal cell arrest.
Estimations of plasma testosterone and urinary oestrogen indicate that testicular steroid biosynthesis is stimulated during treatment with gonadotrophin.
Journal of Endocrinology is committed to supporting researchers in demonstrating the impact of their articles published in the journal.
The two types of article metrics we measure are (i) more traditional full-text views and pdf downloads, and (ii) Altmetric data, which shows the wider impact of articles in a range of non-traditional sources, such as social media.
More information is on the Reasons to publish page.
| Sept 2018 onwards | Past Year | Past 30 Days | |
|---|---|---|---|
| Full Text Views | 0 | 0 | 0 |
| PDF Downloads | 2 | 0 | 0 |
Online ISSN: 1479-6805
Print ISSN: 0022-0795
Strengthening biomedical communities
to advance science and health
CONTACT US
Bioscientifica Ltd | Starling House | 1600 Bristol Parkway North | Bristol BS34 8YU | UK
Bioscientifica Ltd | Registered in England no 3190519
