STUDIES ON GONADOTROPHIN-INDUCED OVULATION IN THE IMMATURE RAT

in Journal of Endocrinology
Authors:
E. T. BELL
Search for other papers by E. T. BELL in
Current site
Google Scholar
PubMed
Close
and
S. F. LUNN
Search for other papers by S. F. LUNN in
Current site
Google Scholar
PubMed
Close
Restricted access
Rent on DeepDyve

Sign up for journal news

SUMMARY

The effect of the administration of 25 i.u. human chorionic gonadotrophin (HCG) on the induction of ovulation in intact immature rats treated with 50 i.u. pregnant mare serum gonadotrophin (PMSG) has been studied.

After the administration of HCG a marked increase in ovarian wet weight was observed. The maximum increase, which occurred 10 hr. after hormone treatment, was noted 2 hr. before ova were found in the oviducts.

The alteration in ovarian wet weight was associated with a fall in percentage solids. However, it appears likely that an increase both in follicular fluid and in cell mass occurred before ovulation. Possible reasons for the absence of any marked effect on uterine wet weight or percentage solids are discussed.

 

  • Collapse
  • Expand