Adult female rats were ovariectomized at various stages of the oestrous cycle; configuration of the vaginal smear and uterine wet weights were determined at various time-intervals after operation.
The results suggested that oestrogen secretion is lowest at oestrus and metoestrus, increases gradually during dioestrus, and continues until the evening of pro-oestrus; progesterone is secreted on the afternoon and evening of pro-oestrus.
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