The 24 hr. 131I uptake in normal neonates has been measured by Fisher, Oddie & Burroughs (1962), Fisher & Oddie (1964), Van Middlesworth (1954) and Ogborn, Waggener & Vanhove (1960), and in the premature infant by Fisher et al. (1962), Martmer, Carrigan, Charbeneau & Sosin (1956), and Gomirato-Sandrucci & Nicola (1958). The results of these studies have been variously interpreted. Van Middles-worth found increased levels (45·5–90%), similar to those in hyperthyroidism in adults, in seven normal infants aged 2–3 days. Martmer et al. considered the uptakes they obtained (15–63%) in premature neonates aged 2–5 days to be within normal limits. Lower values (6·3–36·4%) were obtained by Ogborn et al. (1960) in a similar age group of normal neonates. Gomirato-Sandrucci & Nicola found a higher and more rapid uptake (62·0–93·1%) in premature infants than in normal neonates but no correlation with the degree of prematurity. Fisher et al., in both
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