Hypothyroid, normal and 'thyrotoxic' rats were overheated under standardized conditions, and their rectal temperatures and oxygen consumption were measured. During 30–60 min. of heating, body temperature and oxygen consumption rose more slowly in the hypothyroid animals and more rapidly in the 'thyrotoxic' ones as compared with normal rats. It was also found that, for the same induced increase in body temperature, the oxygen consumption of the hypothyroid rats rose less and that of the 'thyrotoxic' rats more than that of the normal animals.
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