Radioimmunological cross-reactions between human chorionic gonadotrophin and heterologous plasma and pituitary extracts from various species have been examined. Where serial dilutions of a sample do not yield a curve parallel with similar dilutions of the reference standard, quantitative estimations are not possible, but relative potencies can be determined. Such relative potencies against purified heterologous gonadotrophins may be useful for the study of species whose gonadotrophins have not been purified adequately for isotopic labelling in a species-specific radioimmunoassay.
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