In the rat, when luminal continuity was established between the two uterine horns, a unilateral intra-uterine device (IUD) exerted a complete, bilateral contraceptive effect. This was related to the elimination of blastocysts from both uterine horns and to the bilateral inhibition of the decidual cell reaction. Both uterine horns showed leucocytic infiltration into the endometrium, although infiltration was greater in the IUD horn than in the control horn.
When the uterine horns were united without the establishment of luminal continuity a unilateral IUD exerted a strictly unilateral effect, and leucocytic infiltration was only detected in the IUD endometrium and uterine lumen.
These results support the view that the environment within the separate or continuous uterine lumina was altered in the presence of an IUD so that the decidual cell response was inhibited and blastocysts were eliminated. The possibility that this change was related to leucocytic infiltration into the endometrium and uterine lumen cannot be eliminated.
Journal of Endocrinology is committed to supporting researchers in demonstrating the impact of their articles published in the journal.
The two types of article metrics we measure are (i) more traditional full-text views and pdf downloads, and (ii) Altmetric data, which shows the wider impact of articles in a range of non-traditional sources, such as social media.
More information is on the Reasons to publish page.
| Sept 2018 onwards | Past Year | Past 30 Days | |
|---|---|---|---|
| Full Text Views | 3 | 0 | 0 |
| PDF Downloads | 2 | 1 | 0 |
Online ISSN: 1479-6805
Print ISSN: 0022-0795
Strengthening biomedical communities
to advance science and health
CONTACT US
Bioscientifica Ltd | Starling House | 1600 Bristol Parkway North | Bristol BS34 8YU | UK
Bioscientifica Ltd | Registered in England no 3190519
