Because of a misunderstanding, the information on chicken pituitary fractions provided by one of us (A.S.H) was erroneously presented in a paper by two of us (Langslow & Hales, 1969). Figure 1 gives an accurate representation of the purification scheme that was employed together with further information on the pituitary fractions that were used.
The designation of certain fractions as 'GTN residue' and 'GTN supernate' (Langslow & Hales, 1969) is misleading since there is no evidence that either fraction contains significant amounts of glycoprotein or of gonadotrophic activity. The fraction designated GTN precipitate contains follicle-stimulating and luteinizing hormone activities (Stockell Hartree & Cunningham, 1969) and there is suggestive evidence that thyrotrophin is also present (Mitchell, 1967).
The fraction designated crude 'growth hormone' might be expected to contain growth-promoting activity by analogy with corresponding fractions from human and horse pituitaries (Stockell Hartree, 1966; Stockell Hartree, Mills, Welch & Thomas, 1968). However,
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