Testosterone implants releasing about 0·2 mg./day had no effect on sebum production in hypophysectomized-castrated rats, even though treatment by a similar dose of testosterone has been shown to effect a marked increase in sebaceous activity in rats with intact pituitaries.
A preparation of porcine growth hormone, and a preparation of prolactin (luteotrophin) which had no growth hormone activity, were each capable of fully restoring the response of the sebaceous gland in hypophysectomized male rats to testosterone, though the pituitary hormones had no effect by themselves. The stimulation of sebaceous activity was measured both by the increase in sebum production and by the increased incidence of cell division in the sebaceous glands.
The responses of the preputial glands and seminal vesicles to testosterone were independent of the presence of the pituitary, and were not significantly enhanced by the hypophysial hormones.
Journal of Endocrinology is committed to supporting researchers in demonstrating the impact of their articles published in the journal.
The two types of article metrics we measure are (i) more traditional full-text views and pdf downloads, and (ii) Altmetric data, which shows the wider impact of articles in a range of non-traditional sources, such as social media.
More information is on the Reasons to publish page.
| Sept 2018 onwards | Past Year | Past 30 Days | |
|---|---|---|---|
| Full Text Views | 1 | 0 | 0 |
| PDF Downloads | 1 | 0 | 0 |
Online ISSN: 1479-6805
Print ISSN: 0022-0795
Strengthening biomedical communities
to advance science and health
CONTACT US
Bioscientifica Ltd | Starling House | 1600 Bristol Parkway North | Bristol BS34 8YU | UK
Bioscientifica Ltd | Registered in England no 3190519
