Hypophysectomized red-spotted newts [Notophthalmus (Triturus, Diemictylus) viridescens viridescens Rafinesque] received autoplastic, homoplastic or xenoplastic grafts of pituitary glands beneath the lower jaw.
Autografted animals, in accord with previous observations, survived indefinitely. Homografted animals had a mean survival time several times longer than either that of unimplanted, hypophysectomized animals or that of homografts of skin. No difference between rates of iodine turnover was found between thyroid glands of animals with homografts and animals with autografts but in both groups the rates of iodine turnover were lower than in intact controls.
Great variation was found among the mean survival times of animals with xenografts. Newts with pituitary grafts from the frog, Rana pipiens, survived about as long as unimplanted hypophysectomized animals. Pituitary grafts from the salamander, Desmognathus monticola, apparently gave rise to some toxic reaction since their host newts died within short periods of time, yet newts with grafts from the mudpuppy, Necturus maculosus, lived longer than hypophysectomized control animals and some newts grafted with glands from a west coast newt, Taricha torosa, lived indefinitely.
Journal of Endocrinology is committed to supporting researchers in demonstrating the impact of their articles published in the journal.
The two types of article metrics we measure are (i) more traditional full-text views and pdf downloads, and (ii) Altmetric data, which shows the wider impact of articles in a range of non-traditional sources, such as social media.
More information is on the Reasons to publish page.
| Sept 2018 onwards | Past Year | Past 30 Days | |
|---|---|---|---|
| Full Text Views | 3 | 0 | 0 |
| PDF Downloads | 2 | 0 | 0 |
Online ISSN: 1479-6805
Print ISSN: 0022-0795
Strengthening biomedical communities
to advance science and health
CONTACT US
Bioscientifica Ltd | Starling House | 1600 Bristol Parkway North | Bristol BS34 8YU | UK
Bioscientifica Ltd | Registered in England no 3190519
