In mammals several monoamine oxidase inhibitors (MAOI) have been shown to depress the weight and function of the reproductive system (Poulson & Robson, 1964; Zor, Dikstein & Sulman, 1965; Alleva, Overpeck & Umberger, 1966; Zor, Ailabouni & Sulman, 1966; Jaitly, Robson, Sullivan & Wilson, 1968a, b; Zor, Locker, Schleider, & Sulman 1968). The mechanism of action appears to be the ability of the MAOI to (1) inhibit the production of luteinizing hormone (LH) and somatotrophic hormone (STH) (Wickström & Petterson, 1964; Zor et al. 1966) and (2) suppress the release and block the peripheral effects of LH (Zor et al. 1966; Jaitly et al. 1968b). In extending this work to the domestic fowl the present study is concerned with the effects of the MAOI tranylcypromine upon the testis weight of the cockerel.
Single-comb White Leghorn cockerels were injected s.c. for 6 days beginning on the 12th day of
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