Participation of lighting and the pineal gland in neuroendocrine regulation of the gonads is now recognized. The influence of the pineal on gonadal function in male rats involves action on the hypothalamo—hypophysis and on gonadotrophins (Fraschini, Mess & Martini, 1968; Debeljuk, 1969). Direct pineal—gonadal inter-relation has also been postulated since melatonin appears to inhibit steroid biotransformations in vitro (Ellis, 1969).
The effects of light restriction and melatonin administration on accessory sex gland weight and fructose content and incorporation of tritiated thymidine into testicular DNA, as indices of testis function, have been studied in two strains of rat. Effects of pinealectomy were investigated in one strain of rat.
Four groups of seven rats (24–26 days of age) were housed individually at 21 ± 1°. Control animals were exposed to a light:dark (L:D) cycle of 16:8 hr. and light-restricted animals received L:D 1:23 hr. for 24 days. A third group of animals
Journal of Endocrinology is committed to supporting researchers in demonstrating the impact of their articles published in the journal.
The two types of article metrics we measure are (i) more traditional full-text views and pdf downloads, and (ii) Altmetric data, which shows the wider impact of articles in a range of non-traditional sources, such as social media.
More information is on the Reasons to publish page.
| Sept 2018 onwards | Past Year | Past 30 Days | |
|---|---|---|---|
| Full Text Views | 2 | 2 | 0 |
| PDF Downloads | 3 | 2 | 0 |
Online ISSN: 1479-6805
Print ISSN: 0022-0795
Strengthening biomedical communities
to advance science and health
CONTACT US
Bioscientifica Ltd | Starling House | 1600 Bristol Parkway North | Bristol BS34 8YU | UK
Bioscientifica Ltd | Registered in England no 3190519
