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TRANSFORMATION IN VITRO OF [4-14C]DEHYDROEPIANDROSTERONE TO 7-OXYGENATED DERIVATIVES BY NORMAL EARLY HUMAN PLACENTAL TISSUE
in Journal of EndocrinologySUMMARY
Samples from three early human placentae were incubated with [4-14C]-dehydroepiandrosterone (DHA). It was found that [4-14C]DHA was transformed into 7-oxygenated derivatives in yields decreasing in the order: 7-oxo-DHA > 7β-hydroxy-DHA > 7α-hydroxy-DHA. These products were only slowly transformed into other derivatives.
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Online ISSN: 1479-6805
Print ISSN: 0022-0795
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