It is generally accepted that the hypothalamus regulates gonadotrophin secretion by means of specific mediators synthesized in the hypothalamus (Martini, Fraschini & Motta, 1968) and usually called releasing factors. Considering that the gonadotrophin releasing factors are probably peptides (Schally, Arimura, Bowers, Kastin, Sawano & Redding, 1968) and that it is possible to demonstrate an alteration in the amount of these substances in the hypothalamus after gonadectomy (Piacsek & Meites, 1966; Watanabe & McCann, 1969), it was of interest to determine the RNA and protein content of the anterior, middle and posterior hypothalamus in normal and in castrated rats.
Male albino rats fed on the standard diet of the Instituto de Fisiología and weighing 150–180 g were used. Light and temperature were controlled (25 °C, 12 h light and 12 h darkness). Food and water were available ad libitum. Gonadectomy was performed 6 weeks before the animals were decapitated and the
Journal of Endocrinology is committed to supporting researchers in demonstrating the impact of their articles published in the journal.
The two types of article metrics we measure are (i) more traditional full-text views and pdf downloads, and (ii) Altmetric data, which shows the wider impact of articles in a range of non-traditional sources, such as social media.
More information is on the Reasons to publish page.
| Sept 2018 onwards | Past Year | Past 30 Days | |
|---|---|---|---|
| Full Text Views | 6 | 0 | 0 |
| PDF Downloads | 0 | 0 | 0 |
Online ISSN: 1479-6805
Print ISSN: 0022-0795
Strengthening biomedical communities
to advance science and health
CONTACT US
Bioscientifica Ltd | Starling House | 1600 Bristol Parkway North | Bristol BS34 8YU | UK
Bioscientifica Ltd | Registered in England no 3190519
