A RELATIONSHIP BETWEEN SOCIAL EXPERIENCE AND PREPUTIAL GLAND FUNCTION IN THE ALBINO MOUSE

in Journal of Endocrinology
Authors:
F. H. HUCKLEBRIDGE
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N. W. NOWELL
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ANGELA WOUTERS
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The preputial glands are modified sebaceous glands whose size and function are primarily dependent upon the presence of androgens. For this reason they are well developed in the male and vestigial in the female. Their activity is also dependent upon a factor or factors from the pituitary, though the identification of these factors is not yet established (Ebling, Ebling, McCaffery & Skinner, 1971). Experiments by Brain & Nowell (1970) have demonstrated that the isolated mouse, which is more aggressive than the grouped animal, has greater ventral prostate and preputial gland weights, and Mugford & Nowell (1971) have shown that there is a relationship between the presence of the preputial glands and aggressive behaviour, which might be maintained by the release of an aggression-promoting pheromone, in preputial sebum, as a result of hormonal stimulation.

In the course of these latter studies it became obvious that a wide range of preputial activity

 

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