Oestradiol stimulates uterine luminal epithelial cells of ovariectomized mice to pass through two rounds of cell division in quick succession (Das, 1972; Martin, Finn & Trinder, 1973). Progesterone injected with the oestrogen blocks entry of some cells into the first round of proliferation without affecting G1, S or G2 in the remainder, but blocks entry of these cells into the second round. This suggested that cells were only sensitive to progesterone in early G1 (Martin, Das & Finn, 1973). In the present experiment we attempted to delineate the sensitive period in greater detail.
Randomly bred albino mice were ovariectomized and primed as described previously (Das, 1972). Five days after priming they were separated into ten groups of three. All were given 50 ng oestradiol subcutaneously in 0·1 ml arachis oil at 0 h and 25 μCi [3H]thymidine ([3H]Thd; sp. act. 5 Ci/mm, Amersham) intraperitoneally
Journal of Endocrinology is committed to supporting researchers in demonstrating the impact of their articles published in the journal.
The two types of article metrics we measure are (i) more traditional full-text views and pdf downloads, and (ii) Altmetric data, which shows the wider impact of articles in a range of non-traditional sources, such as social media.
More information is on the Reasons to publish page.
| Sept 2018 onwards | Past Year | Past 30 Days | |
|---|---|---|---|
| Full Text Views | 4 | 0 | 0 |
| PDF Downloads | 1 | 0 | 0 |
Online ISSN: 1479-6805
Print ISSN: 0022-0795
Strengthening biomedical communities
to advance science and health
CONTACT US
Bioscientifica Ltd | Starling House | 1600 Bristol Parkway North | Bristol BS34 8YU | UK
Bioscientifica Ltd | Registered in England no 3190519
