EFFECTS OF ANDROGEN ON THE AVERSIVE PROPERTIES OF MALE MOUSE URINE

in Journal of Endocrinology
Authors:
R. B. JONES
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N. W. NOWELL
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SUMMARY

The aversive properties of urine of castrated male mice receiving varying doses of testosterone phenylpropionate was assayed using males housed in groups of six as subjects. The aversive efficacy of the urine was found to rise with an increase in androgen levels. There was a delay of 5 days before the exogenous androgen exerted any effect on the aversive properties of the urine. This delay indicated that the aversive factor might be a pheromonal substance released from an androgen-dependent tissue, rather than being an excreted androgen metabolite.

The results are discussed in terms of androgen levels and possible territorial functions.

 

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