The sequence of changes in gonadotrophin and/or sex hormone secretion observed during the sex cycle and the difference in the type of gonadotrophin control between male and female rats, can be related to changes in hypothalamic glucose oxidation (Scacchi, Moguilevsky & Schiaffini, 1973). This paper presents an attempt to determine whether a similar process to the one observed in the hypothalamus occurs in the limbic system, since this tissue is directly affected by gonadotrophin levels (Schiaffini & Martini, 1972).
The production of 14CO2 from [U-14C]glucose in the amygdala and hippocampus of albino rats was determined by the methods described in a previous paper (Scacchi et al. 1973). Cerebral cortex from the frontal region was used as control tissue. The following experimental groups were established: (a) female rats in dioestrus; (b) in pro-oestrus; (c) in oestrus; (d) ovariectomized and used 7 days after gonadectomy; (e) ovariectomized and
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