CHANGES IN THE CONCENTRATIONS OF CORTISOL AND CORTICOSTERONE IN THE PLASMA AND ADRENAL GLANDS OF THE GUINEA-PIG FROM BIRTH TO WEANING

in Journal of Endocrinology
Authors:
M. DALLE
Search for other papers by M. DALLE in
Current site
Google Scholar
PubMed
Close
and
P. DELOST
Search for other papers by P. DELOST in
Current site
Google Scholar
PubMed
Close
Restricted access
Rent on DeepDyve

Sign up for journal news

SUMMARY

Concentrations of cortisol and corticosterone in the plasma and adrenal glands of male and female guinea-pigs were estimated throughout the first postnatal day and thereafter at intervals up to 3 weeks of age. In the guinea-pig, the basal level of cortisol secretion is established more slowly than in other species. The concentration of plasma cortisol is very high at birth, with a marked fall between days 1 and 10 post partum and then a steady level from day 10 to 20, the time of weaning. At day 10 the values for plasma cortisol and corticosterone approach the lower ones found in the adult. There were peaks in the amounts of corticosteroids found in the adrenal gland at 50 h, 4 and 7 days and these may have been due to increased hormonal synthesis between days 2 and 8.

 

  • Collapse
  • Expand