Departments of Obstetrics and Gynecology, and *Anatomy, Hahnemann Medical College and Hospital, Philadelphia, Pennsylvania 19102, U.S.A.
(Received 9 September 1974)
Since the cellular composition of peritoneal fluid is altered by species, sex (Davis & McGowan, 1968), the oestrous (McGowan & Davis, 1968) and menstrual cycles (McGowan, Davis, Stein, Bebon & Vaskelis, 1968) as well as pregnancy (McGowan, Davis & Kriesler, 1968; McGowan & Davis, 1969), we believe that the cellular content of peritoneal fluid is affected in a characteristic manner by administration of hormones. Testosterone injected into castrated mice increases the percentages of mesothelial cells and histiocytes in serous fluid, with a corresponding decrease in bare nuclei (Davis, McGowan & Villanueva, 1969). On the other hand, oestrogen given to ovariectomized mice reduces the proportion of mesothelial cells and causes 'daisy cells' to appear in aspirated fluid (McGowan & Davis, 1970). Subcutaneous administration of cortisone also decreases the proportions of mesothelial
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