University of Chicago, Pritzker School of Medicine, Chicago, Illinois 60637, U.S.A.
(Received 18 July 1975)
The biochemical basis of the genetically determined difference in sexual hair growth between oriental and caucasian men has not been established. Oriental men have plasma testosterone levels equal to those of Occidentals. However, the former group has low 17-oxosteroid excretion and beard growth can be induced by androgen, findings compatible with hypoandrogenism (Kobayashi, Lobotsky & Lloyd, 1966). Available data do not exclude differences in plasma testosterone binding or levels of other androgens. Therefore, the following studies were undertaken.
Six, 24 ± 0·81 (S.D.) -year-old normal graduate students of oriental descent (3 Chinese, 3 Japanese) who were unable to grow beard, moustache, or sideburns were compared with six, 24 ± 4·6-year-old, Caucasian graduate students who were fully virile. Hormone levels were measured in single, fasting, 08.00 h blood specimens.
Plasma testosterone, androstenedione, dihydrotestosterone, and dehydroepiandrosterone (DHA) were
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