I.N.R.A., Theix, 63110 Beaumont, France
(Received 17 October 1975)
Calcitonin deficiency (induced by thyroidectomy) has been shown to be associated with a wasteful loss of calcium in the urine in rats (Munson, Cooper, Gray, Peng, Toverud, Harper & Ontjes, 1973) and goats (Barlet & Garel, 1975). In the work reported here, we have investigated the influence of calcitonin (CT) on renal calcium and phosphate content in lambs.
In the first experiment thirteen 2-month-old weaned (22-24 kg body wt) female lambs were used. Seven of them had been surgically thyroidectomized (TX) (the upper parathyroid glands being left intact) 10 days before the beginning of the experiment. Five days after the operation these seven TX lambs were supplemented with thyroxine (T4) (200 μg/animal/day) so that plasma hormonal iodine levels were not statistically different in TX (3·10 ± 0·47 (s.e.m.) μg/100 ml) and in intact control animals (3·27 ± 0·58 μg/100ml). During the experimental period (40 days) each animal ingested 6 g calcium, 2 g magnesium and 9 g phosphate daily. At the time of slaughtering, the right kidney of each animal
Journal of Endocrinology is committed to supporting researchers in demonstrating the impact of their articles published in the journal.
The two types of article metrics we measure are (i) more traditional full-text views and pdf downloads, and (ii) Altmetric data, which shows the wider impact of articles in a range of non-traditional sources, such as social media.
More information is on the Reasons to publish page.
| Sept 2018 onwards | Past Year | Past 30 Days | |
|---|---|---|---|
| Full Text Views | 0 | 0 | 0 |
| PDF Downloads | 2 | 0 | 0 |
Online ISSN: 1479-6805
Print ISSN: 0022-0795
Strengthening biomedical communities
to advance science and health
CONTACT US
Bioscientifica Ltd | Starling House | 1600 Bristol Parkway North | Bristol BS34 8YU | UK
Bioscientifica Ltd | Registered in England no 3190519
