PRECOCIOUS 'FEMINIZATION' OF RAT LIVER ENZYMES IN THE PRESENCE OF ECTOPIC PITUITARY TISSUE

in Journal of Endocrinology
Authors:
JAN-ÅKE GUSTAFSSON
Search for other papers by JAN-ÅKE GUSTAFSSON in
Current site
Google Scholar
PubMed
Close
and
PAUL SKETT
Search for other papers by PAUL SKETT in
Current site
Google Scholar
PubMed
Close
Restricted access
Rent on DeepDyve

Sign up for journal news

The presence of ectopic pituitary tissue (derived from an adult rat) in prepubertal male and female rats caused the immature, masculine-type hepatic steroid metabolism to develop into female-type metabolism. It is concluded that the hypothalamus–pituitary system controls the ontogenesis of sex-dependent steroid metabolism in rat liver.

 

  • Collapse
  • Expand