EFFECT OF ADRENALECTOMY AND HORMONE REPLACEMENT ON SODIUM AND WATER TRANSPORT IN THE PERFUSED RAT CAUDA EPIDIDYMIDIS

in Journal of Endocrinology
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C. L. AU
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H. K. NGAI
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C. H. YEUNG
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P. Y. D. WONG
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Department of Physiology, Faculty of Medicine, University of Hong Kong, Li Shu Fan Building, Sassoon Road, Hong Kong

(Received 22 November 1977)

The rat testis secretes fluid (Tuck, Setchell, Waites & Young, 1970; Cheung, Hwang & Wong, 1977) which is reabsorbed by the epididymis (Crabo & Gustafsson, 1964; Levine & Marsh, 1971). In the cauda epididymidis, sodium chloride is reabsorbed isotonically with water and potassium is secreted into the ductal lumen (Wong & Yeung, 1977, 1978); these transport processes seem to have many characteristics typical of the processes occurring in the distal tubule of the kidney. Apart from electrolyte and water transport, proteins are also secreted into the ductal lumen. The epididymal epithelium actively maintains a definite milieu within the tubule in which the spermatozoa are maturing. In several transporting epithelia such as those of the toad bladder, frog skin, salivary and sweat glands, intestine and renal tubule (for references,

 

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