This present study has demonstrated that during normal pregnancy in the rat the number of β-cells is increased (hyperplasia) and the volume of the individual β-cells is increased (hypertrophy).
During experimental diabetes, however, the endocrine pancreas has an impaired capacity to compensate during pregnancy. In the experimental diabetic pregnant rat the β-cells cannot replicate due to the unfavourable metabolic environment. This could reflect the complications caused by diabetes during human pregnancy.
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| Sept 2018 onwards | Past Year | Past 30 Days | |
|---|---|---|---|
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Online ISSN: 1479-6805
Print ISSN: 0022-0795
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