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Rui Gao Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK

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Samuel Acreman Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK
Department of Physiology, Institute of Neuroscience and Physiology, Metabolic Research Unit, University of Gothenburg, Göteborg, Sweden

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Jinfang Ma Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK

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Fernando Abdulkader Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil

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Anna Wendt Department of Clinical Sciences Malmö, Islet Cell Exocytosis, Lund University Diabetes Centre, Lund University, Malmö, Sweden

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Quan Zhang Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK
CNC - Center for Neuroscience and Cell Biology, CIBB - Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, Coimbra, Portugal

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intracellular metabolites (i.e. ATP and cAMP). CFTR-mediated Cl- efflux regulates the membrane potential through an intrinsic α-cell effect, also resulting in the inhibition of glucagon secretion. AC, adenylyl cyclase; FFA, free fatty acids; CPT1a, carnitine

Article Type:
Review Article
Collections:
100 years of glucagon: Anniversary collection
DOI:
https://doi.org/10.1530/JOE-22-0295
Volume/Issue:
Volume 258: Issue 2
Open access
Esther Dos Santos Service de Biochimie et Biologie Moléculaire, UPRES EA 2493, Faculté de Médecine Paris-Ile de France Ouest, Centre hospitalier de Poissy, Université Versailles St Quentin, 78303 Poissy Cedex, France

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Marie-Noëlle Dieudonné Service de Biochimie et Biologie Moléculaire, UPRES EA 2493, Faculté de Médecine Paris-Ile de France Ouest, Centre hospitalier de Poissy, Université Versailles St Quentin, 78303 Poissy Cedex, France

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Marie-Christine Leneveu Service de Biochimie et Biologie Moléculaire, UPRES EA 2493, Faculté de Médecine Paris-Ile de France Ouest, Centre hospitalier de Poissy, Université Versailles St Quentin, 78303 Poissy Cedex, France

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René Pecquery Service de Biochimie et Biologie Moléculaire, UPRES EA 2493, Faculté de Médecine Paris-Ile de France Ouest, Centre hospitalier de Poissy, Université Versailles St Quentin, 78303 Poissy Cedex, France

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Valérie Serazin Service de Biochimie et Biologie Moléculaire, UPRES EA 2493, Faculté de Médecine Paris-Ile de France Ouest, Centre hospitalier de Poissy, Université Versailles St Quentin, 78303 Poissy Cedex, France

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Yves Giudicelli Service de Biochimie et Biologie Moléculaire, UPRES EA 2493, Faculté de Médecine Paris-Ile de France Ouest, Centre hospitalier de Poissy, Université Versailles St Quentin, 78303 Poissy Cedex, France

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concentrations were measured following a radiocompetition assay as described in Gaben-Cogneville et al. (1984) . Forskolin (10 μ M), the adenylyl cyclase activator, was used as a positive control at the 15 min time point. Lipolysis

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-06-0101
Volume/Issue:
Volume 194: Issue 2
Free access
Glyn M Noguchi Department of Neurobiology, Physiology & Behavior, University of California Davis, Davis, California, USA

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Vincent C Castillo Department of Neurobiology, Physiology & Behavior, University of California Davis, Davis, California, USA

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Cynthia J Donaldson Salk Institute for Biological Studies, La Jolla, California, USA

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Marcus R Flisher Department of Neurobiology, Physiology & Behavior, University of California Davis, Davis, California, USA

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Ariana T Momen Department of Neurobiology, Physiology & Behavior, University of California Davis, Davis, California, USA

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Alan Saghatelian Salk Institute for Biological Studies, La Jolla, California, USA

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Mark O Huising Department of Neurobiology, Physiology & Behavior, University of California Davis, Davis, California, USA
Department of Physiology & Membrane Biology, University of California Davis, Davis, California, USA

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. 2001 ) expressed specifically by delta cells ( van der Meulen et al. 2015 , DiGruccio et al. 2016 ). In line with this G α s signaling mechanism that increases delta cell adenylyl cyclase activity and cAMP levels, blocking cAMP in delta cells

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-24-0018
Volume/Issue:
Volume 261: Issue 3
Restricted access
María Andrea Camilletti Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina

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Alejandra Abeledo-Machado Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina

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Jimena Ferraris Instituto de Investigaciones Biomédicas, Facultad de Medicina, Universidad de Buenos Aires-CONICET, Buenos Aires, Argentina

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Pablo A Pérez Centro de Microscopia Electrónica, Instituto de Investigaciones en Ciencias de la Salud (INICSA-CONICET), Facultad de Ciencias Medicas, Universidad Nacional de Córdoba, Córdoba, Argentina

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Erika Y Faraoni Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina

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Daniel Pisera Instituto de Investigaciones Biomédicas, Facultad de Medicina, Universidad de Buenos Aires-CONICET, Buenos Aires, Argentina

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Silvina Gutierrez Centro de Microscopia Electrónica, Instituto de Investigaciones en Ciencias de la Salud (INICSA-CONICET), Facultad de Ciencias Medicas, Universidad Nacional de Córdoba, Córdoba, Argentina

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Graciela Díaz-Torga Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina

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.1210/mend.14.10.0532 Filardo EJ Quinn JA Frackelton AR Jr Bland KI 2002 Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-18-0402
Volume/Issue:
Volume 240: Issue 2
Free access
Ingrid Segers Follicle Biology Laboratory, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090 Jette, Belgium

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Tom Adriaenssens Follicle Biology Laboratory, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090 Jette, Belgium

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Sandra Wathlet Follicle Biology Laboratory, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090 Jette, Belgium

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Johan Smitz Follicle Biology Laboratory, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090 Jette, Belgium

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gonadotropin preparation, urinary or recombinant, might, via isoform composition differences, affect bioavailability and bioactivity in relation to the species ( de Leeuw et al . 1996 ). Gonadotropin receptors typically activate adenylyl cyclase through G

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-12-0150
Volume/Issue:
Volume 215: Issue 2
Free access
Ynuk Bossé Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec, Québec, Canada G1V 4G5

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2012 The dopamine D(2) receptor is expressed and sensitizes adenylyl cyclase activity in airway smooth muscle . American Journal of Physiology. Lung Cellular and Molecular Physiology 302 L316 – L324 . ( doi:10.1152/ajplung.00130.2011 ) Montano

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-14-0220
Volume/Issue:
Volume 222: Issue 2
Free access
Michael Rouse Laboratory of Clinical Investigation, Laboratory of Cardiovascular Science, National Institute on Aging, Intramural Research Program, National Institutes of Health, 251 Bayview Blvd, Baltimore, Maryland 21224, USA

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Antoine Younès Laboratory of Clinical Investigation, Laboratory of Cardiovascular Science, National Institute on Aging, Intramural Research Program, National Institutes of Health, 251 Bayview Blvd, Baltimore, Maryland 21224, USA

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Josephine M Egan Laboratory of Clinical Investigation, Laboratory of Cardiovascular Science, National Institute on Aging, Intramural Research Program, National Institutes of Health, 251 Bayview Blvd, Baltimore, Maryland 21224, USA

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Resveratrol activates adenylyl-cyclase in human breast cancer cells: a novel, estrogen receptor-independent cytostatic mechanism . Carcinogenesis 24 869 – 873 . ( doi:10.1093/carcin/bgg015 ) Fan X Zhang C Liu D Yan J Liang H 2013 The

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-14-0335
Volume/Issue:
Volume 223: Issue 2
Open access
Marcello Maggiolini
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Didier Picard Department of Pharmaco-Biology, Département de Biologie Cellulaire, University of Calabria, 87030 Rende, Italy

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Endocrinology 14 1649 – 1660 . Filardo EJ Quinn JA Frackelton AR Jr Bland KI 2002 Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-09-0242
Volume/Issue:
Volume 204: Issue 2
Free access
Nabanita S Datta Division of Endocrinology, Department of Internal Medicine, Wayne State University School of Medicine, 1107 Elliman Building, 421 East Canfield Avenue, Detroit, Michigan 48201, USA

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Tareq A Samra Division of Endocrinology, Department of Internal Medicine, Wayne State University School of Medicine, 1107 Elliman Building, 421 East Canfield Avenue, Detroit, Michigan 48201, USA

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Chandrika D Mahalingam Division of Endocrinology, Department of Internal Medicine, Wayne State University School of Medicine, 1107 Elliman Building, 421 East Canfield Avenue, Detroit, Michigan 48201, USA

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Tanuka Datta Division of Endocrinology, Department of Internal Medicine, Wayne State University School of Medicine, 1107 Elliman Building, 421 East Canfield Avenue, Detroit, Michigan 48201, USA

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Abdul B Abou-Samra Division of Endocrinology, Department of Internal Medicine, Wayne State University School of Medicine, 1107 Elliman Building, 421 East Canfield Avenue, Detroit, Michigan 48201, USA

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(PTH) and 24,25-dihydroxy-vitamin D 3 on adenylyl cyclase of iliac crest biopsies: diagnostic and prognostic tool for evaluation and treatment of uremic patients . Scandinavian Journal of Clinical and Laboratory Investigation. Supplement 186 13

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-10-0227
Volume/Issue:
Volume 207: Issue 3
Free access
Srividya Vasu SAAD Centre for Pharmacy & Diabetes, School of Biomedical Sciences, University of Ulster, Coleraine, UK

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Mary K McGahon Centre for Experimental Medicine, Queens University of Belfast, Belfast, UK

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R Charlotte Moffett SAAD Centre for Pharmacy & Diabetes, School of Biomedical Sciences, University of Ulster, Coleraine, UK

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Tim M Curtis Centre for Experimental Medicine, Queens University of Belfast, Belfast, UK

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J Michael Conlon SAAD Centre for Pharmacy & Diabetes, School of Biomedical Sciences, University of Ulster, Coleraine, UK

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Yasser H A Abdel-Wahab SAAD Centre for Pharmacy & Diabetes, School of Biomedical Sciences, University of Ulster, Coleraine, UK

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Peter R Flatt SAAD Centre for Pharmacy & Diabetes, School of Biomedical Sciences, University of Ulster, Coleraine, UK

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Zippin JH Kamenetsky M Buck J Levin LR 2008 Glucose and GLP-1 stimulate cAMP production via distinct adenylyl cyclases in INS-1E insulinoma cells . Journal of General Physiology 132 329 – 338 . ( doi:10.1085/jgp.200810044

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-16-0453
Volume/Issue:
Volume 232: Issue 3
Free access