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Ana Sánchez-Tusie Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México

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Carlos Montes de Oca Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México

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Julia Rodríguez-Castelán Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México

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Evangelina Delgado-González Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México

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Zamira Ortiz Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México

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Lourdes Álvarez Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México

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Carlos Zarco Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México

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Carmen Aceves Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México

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Brenda Anguiano Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México

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found at baseline a low TRβ/TRα1 ratio in TRAMP. The high T 3 dose increased this ratio two-fold in WT and four-fold in TRAMP. Figure 3 Expression and immunolocalization of thyroid hormone receptors. (A) mRNA levels of TRα1 and TRβ were

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Simona Michienzi Chair of Endocrinology, II Faculty of Medicine, University La Sapienza, Rome, Italy
Centro Ricerca AFaR, Ospedale San Pietro FBF, Via Cassia 600, 00189, Rome, Italy
Istituto Dermopatico dell’Immacolata, IDI, IRCSS, Rome, Italy

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Barbara Bucci Chair of Endocrinology, II Faculty of Medicine, University La Sapienza, Rome, Italy
Centro Ricerca AFaR, Ospedale San Pietro FBF, Via Cassia 600, 00189, Rome, Italy
Istituto Dermopatico dell’Immacolata, IDI, IRCSS, Rome, Italy

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Cecilia Verga Falzacappa Chair of Endocrinology, II Faculty of Medicine, University La Sapienza, Rome, Italy
Centro Ricerca AFaR, Ospedale San Pietro FBF, Via Cassia 600, 00189, Rome, Italy
Istituto Dermopatico dell’Immacolata, IDI, IRCSS, Rome, Italy

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Valentina Patriarca Chair of Endocrinology, II Faculty of Medicine, University La Sapienza, Rome, Italy
Centro Ricerca AFaR, Ospedale San Pietro FBF, Via Cassia 600, 00189, Rome, Italy
Istituto Dermopatico dell’Immacolata, IDI, IRCSS, Rome, Italy

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Antonio Stigliano Chair of Endocrinology, II Faculty of Medicine, University La Sapienza, Rome, Italy
Centro Ricerca AFaR, Ospedale San Pietro FBF, Via Cassia 600, 00189, Rome, Italy
Istituto Dermopatico dell’Immacolata, IDI, IRCSS, Rome, Italy

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Laura Panacchia Chair of Endocrinology, II Faculty of Medicine, University La Sapienza, Rome, Italy
Centro Ricerca AFaR, Ospedale San Pietro FBF, Via Cassia 600, 00189, Rome, Italy
Istituto Dermopatico dell’Immacolata, IDI, IRCSS, Rome, Italy

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Ercole Brunetti Chair of Endocrinology, II Faculty of Medicine, University La Sapienza, Rome, Italy
Centro Ricerca AFaR, Ospedale San Pietro FBF, Via Cassia 600, 00189, Rome, Italy
Istituto Dermopatico dell’Immacolata, IDI, IRCSS, Rome, Italy

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Vincenzo Toscano Chair of Endocrinology, II Faculty of Medicine, University La Sapienza, Rome, Italy
Centro Ricerca AFaR, Ospedale San Pietro FBF, Via Cassia 600, 00189, Rome, Italy
Istituto Dermopatico dell’Immacolata, IDI, IRCSS, Rome, Italy

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Silvia Misiti Chair of Endocrinology, II Faculty of Medicine, University La Sapienza, Rome, Italy
Centro Ricerca AFaR, Ospedale San Pietro FBF, Via Cassia 600, 00189, Rome, Italy
Istituto Dermopatico dell’Immacolata, IDI, IRCSS, Rome, Italy

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-mediated growth arrest has been observed in different cell lines including rat chondrocyte primary culture ( Ballock et al. 2000 ), murine neuroblastoma N2a-β cells that overexpress the thyroid hormone receptor β 1 isoform ( Perez-Juste & Aranda 1999

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B Anguiano Instituto de Neurobiología, UNAM-Juriquilla, Querétaro, México 76230

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R Rojas-Huidobro Instituto de Neurobiología, UNAM-Juriquilla, Querétaro, México 76230

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G Delgado Instituto de Neurobiología, UNAM-Juriquilla, Querétaro, México 76230

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C Aceves Instituto de Neurobiología, UNAM-Juriquilla, Querétaro, México 76230

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thyroid hormone receptors β and α1 in regulation of type 1 deiodinase expression. Molecular Endocrinology 15 467 –475. Anderson GW , Mariash CN & Opperheimer JH 2000 Thyroid hormone action. In Werner and Ingbar’s The

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Joachim Wistuba Institute of Reproductive Medicine of the University, Domagkstr. 11, 48149 Münster, Germany
Department of Neuroendocrinology, Max-Planck-Institute for Experimental Endocrinology, Feodor-Lynen-Str. 7, 30625 Hannover, Germany

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Jens Mittag Institute of Reproductive Medicine of the University, Domagkstr. 11, 48149 Münster, Germany
Department of Neuroendocrinology, Max-Planck-Institute for Experimental Endocrinology, Feodor-Lynen-Str. 7, 30625 Hannover, Germany

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C Marc Luetjens Institute of Reproductive Medicine of the University, Domagkstr. 11, 48149 Münster, Germany
Department of Neuroendocrinology, Max-Planck-Institute for Experimental Endocrinology, Feodor-Lynen-Str. 7, 30625 Hannover, Germany

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Trevor G Cooper Institute of Reproductive Medicine of the University, Domagkstr. 11, 48149 Münster, Germany
Department of Neuroendocrinology, Max-Planck-Institute for Experimental Endocrinology, Feodor-Lynen-Str. 7, 30625 Hannover, Germany

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Ching-Hei Yeung Institute of Reproductive Medicine of the University, Domagkstr. 11, 48149 Münster, Germany
Department of Neuroendocrinology, Max-Planck-Institute for Experimental Endocrinology, Feodor-Lynen-Str. 7, 30625 Hannover, Germany

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Eberhard Nieschlag Institute of Reproductive Medicine of the University, Domagkstr. 11, 48149 Münster, Germany
Department of Neuroendocrinology, Max-Planck-Institute for Experimental Endocrinology, Feodor-Lynen-Str. 7, 30625 Hannover, Germany

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Karl Bauer Institute of Reproductive Medicine of the University, Domagkstr. 11, 48149 Münster, Germany
Department of Neuroendocrinology, Max-Planck-Institute for Experimental Endocrinology, Feodor-Lynen-Str. 7, 30625 Hannover, Germany

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Endocrinology 105 39 –46. Chassande O 2003 Do unliganded thyroid hormone receptors have physiological functions? Journal of Molecular Endocrinology 31 9 –20. Choksi NY , Jahnke GD, St Hilaire C

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Giuseppe Calamita Department of General and Environmental Physiology, Università degli Studi di Bari, Via Amendola 165/A, 70126 Bari, Italy
Department of Biological and Environmental Sciences, University of Sannio, Via Port’Arsa 11, 82100 Benevento, Italy
Department of Zoology, University of Bari, Bari, Italy

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Maria Moreno Department of General and Environmental Physiology, Università degli Studi di Bari, Via Amendola 165/A, 70126 Bari, Italy
Department of Biological and Environmental Sciences, University of Sannio, Via Port’Arsa 11, 82100 Benevento, Italy
Department of Zoology, University of Bari, Bari, Italy

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Domenico Ferri Department of General and Environmental Physiology, Università degli Studi di Bari, Via Amendola 165/A, 70126 Bari, Italy
Department of Biological and Environmental Sciences, University of Sannio, Via Port’Arsa 11, 82100 Benevento, Italy
Department of Zoology, University of Bari, Bari, Italy

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Elena Silvestri Department of General and Environmental Physiology, Università degli Studi di Bari, Via Amendola 165/A, 70126 Bari, Italy
Department of Biological and Environmental Sciences, University of Sannio, Via Port’Arsa 11, 82100 Benevento, Italy
Department of Zoology, University of Bari, Bari, Italy

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Patrizia Roberti Department of General and Environmental Physiology, Università degli Studi di Bari, Via Amendola 165/A, 70126 Bari, Italy
Department of Biological and Environmental Sciences, University of Sannio, Via Port’Arsa 11, 82100 Benevento, Italy
Department of Zoology, University of Bari, Bari, Italy

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Luigi Schiavo Department of General and Environmental Physiology, Università degli Studi di Bari, Via Amendola 165/A, 70126 Bari, Italy
Department of Biological and Environmental Sciences, University of Sannio, Via Port’Arsa 11, 82100 Benevento, Italy
Department of Zoology, University of Bari, Bari, Italy

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Patrizia Gena Department of General and Environmental Physiology, Università degli Studi di Bari, Via Amendola 165/A, 70126 Bari, Italy
Department of Biological and Environmental Sciences, University of Sannio, Via Port’Arsa 11, 82100 Benevento, Italy
Department of Zoology, University of Bari, Bari, Italy

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Maria Svelto Department of General and Environmental Physiology, Università degli Studi di Bari, Via Amendola 165/A, 70126 Bari, Italy
Department of Biological and Environmental Sciences, University of Sannio, Via Port’Arsa 11, 82100 Benevento, Italy
Department of Zoology, University of Bari, Bari, Italy

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Fernando Goglia Department of General and Environmental Physiology, Università degli Studi di Bari, Via Amendola 165/A, 70126 Bari, Italy
Department of Biological and Environmental Sciences, University of Sannio, Via Port’Arsa 11, 82100 Benevento, Italy
Department of Zoology, University of Bari, Bari, Italy

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rats suggest that the downregulation of AQP8 by T3 may well be due to a T3-dependent interaction of thyroid hormone receptor with putative negative thyroid hormone response elements (nTRE; Crone et al. 1990 ) contained in the AQP8 promoter. This

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Sinead N Kelly Department of Surgery, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland
Department of Endocrinology and Diabetes Mellitus, St Vincent’s University Hospital, Elm Park, Dublin, Ireland

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T Joseph McKenna Department of Surgery, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland
Department of Endocrinology and Diabetes Mellitus, St Vincent’s University Hospital, Elm Park, Dublin, Ireland

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Leonie S Young Department of Surgery, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland
Department of Endocrinology and Diabetes Mellitus, St Vincent’s University Hospital, Elm Park, Dublin, Ireland

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(ACTR), AIB-I, CBP interacting protein). Conversely, corepressors such as silencing mediator for retinoid and thyroid hormone receptor (SMRT) interact strongly with nuclear receptors under basal conditions and this interaction is thought to be

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Shu-Fang Xia Wuxi School of Medicine, Jiangnan University, Wuxi, China
State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, China

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Xiao-Mei Duan State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, China
Shandong Sport Training Center, Jinan, China

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Xiang-Rong Cheng State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, China

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Li-Mei Chen Wuxi School of Medicine, Jiangnan University, Wuxi, China

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Yan-Jun Kang Wuxi School of Medicine, Jiangnan University, Wuxi, China

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Peng Wang COFCO Corporation Oilseeds Processing Division, Beijing, China

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Xue Tang State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, China

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Yong-Hui Shi State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, China

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Guo-Wei Le State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, China

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2011 Thyroid Hormone Receptor beta (THRB) is a major target gene for microRNAs deregulated in Papillary Thyroid Carcinoma (PTC) . Journal of Clinical Endocrinology and Metabolism 96 546 – 553 . ( doi:10.1210/jc.2010-1594 ) 10.1210/jc.2010

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Diletta Piccirilli Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy

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Enke Baldini Department of Surgical Sciences, ‘Sapienza’ University of Rome, Rome, Italy

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Micol Massimiani Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy

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Antonella Camaioni Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy

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Antonietta Salustri Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy

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Roberta Bernardini Department of Biology, NSTA, II University of Rome, Tor Vergata, Italy

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Marco Centanni Department of Medico-Surgical Sciences and Biotechnologies, ‘Sapienza’ University of Rome, Latina, Italy

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Salvatore Ulisse Department of Surgical Sciences, ‘Sapienza’ University of Rome, Rome, Italy

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Costanzo Moretti Department of Systems’ Medicine University of Rome Tor Vergata, UOC of Endocrinology and Diabetes, Section of Reproductive Endocrinology Fatebenefratelli Hospital, ‘Isola Tiberina’, Rome, Italy

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Luisa Campagnolo Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy

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bovine embryo development in vitro ( Aghajanova et al . 2011 , Costa et al . 2013 ). In vivo , thyroid hormone receptor (TR) and thyrotropin receptor are expressed in the endometrium, and their expression in endometrial cells is concomitant with the

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Nicolás Gigena Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina

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Vanina A Alamino Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina

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María del Mar Montesinos Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina

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Magalí Nazar Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina

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Ruy A Louzada Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Centro de Ciências da Saúde, Rio de Janeiro, Brazil

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Simone M Wajner Thyroid Unit, Endocrinology Division, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil

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Ana L Maia Thyroid Unit, Endocrinology Division, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil

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Ana M Masini-Repiso Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina

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Denise P Carvalho Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Centro de Ciências da Saúde, Rio de Janeiro, Brazil

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Graciela A Cremaschi Laboratorio de Neuroinmunomodulación y Oncología Molecular, Instituto de Investigaciones Biomédicas (BIOMED-CONICET), Universidad Católica Argentina, Ciudad Autónoma de Buenos Aires, Argentina

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Claudia G Pellizas Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina

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MM Gigena N Donadio AC Blidner AG Milotich SI Cheng SY Masini-Repiso AM Rabinovich GA 2015 Antitumor responses stimulated by dendritic cells are improved by triiodothyronine binding to the thyroid hormone receptor beta

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Aline Cordeiro
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Luana Lopes de Souza
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Lorraine Soares Oliveira
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Larissa Costa Faustino
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Letícia Aragão Santiago
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Flavia Fonseca Bloise
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Tania Maria Ortiga-Carvalho
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Norma Aparecida dos Santos Almeida Biophysics Institute Carlos Chagas Filho, Department of Physiological Sciences, Federal University of Rio de Janeiro, Cidade Universitária - Ilha do Fundão, Avenida Carlos Chagas Filho, 373, Centro de Ciências da Saúde, Bloco G, CEP: 21941-902, Rio de Janeiro, RJ, Brazil

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Carmen Cabanelas Pazos-Moura
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-CoA synthetases . PNAS 103 10230 – 10235 . ( doi:10.1073/pnas.0604392103 ) Hashimoto K Curty FH Borges PP Lee CE Abel ED Elmquist JK Cohen RN Wondisford FE 2001 An unliganded thyroid hormone receptor causes severe neurological dysfunction

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