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Jie Wei, Xia Sun, Yajie Chen, Yuanyuan Li, Liqiong Song, Zhao Zhou, Bing Xu, Yi Lin, and Shunqing Xu

adult male CD1 mice to BPA (0, 5, 50, 500, and 5000 μg/kg per day) resulted in the accumulation of hepatic triglycerides (TGs) and cholesteryl esters (CHOL), changes in hepatic free fatty acid (FFA) composition as well as upregulation of genes involved

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Barbara J Clark

? ? ? The thioesterase multidomain proteins STARD14 ACOT11_v2, BFIT2 Brown adipose tissue † Cytosolic c ? Fatty acid d (?) Medium chain fatty-acyl-coA hydrolysis 10 STARD15 ACOT12 Liver † Cytosolic c ? Acetyl-coA hydrolysis 11 StAR, steroidogenic acute

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Blerina Kola and Márta Korbonits

intracellular Ca 2 + levels. Ghrelin has a unique fatty acid modification on its N-terminal end as a result of the activity of the ghrelin O -acyltransferase enzyme ( Yang et al . 2008 ). However, the majority of circulating ghrelin is actually lacking this

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Ken Takao, Katsumi Iizuka, Yanyan Liu, Teruaki Sakurai, Sodai Kubota, Saki Kubota-Okamoto, Toshinori Imaizumi, Yoshihiro Takahashi, Yermek Rakhat, Satoko Komori, Tokuyuki Hirose, Kenta Nonomura, Takehiro Kato, Masami Mizuno, Tetsuya Suwa, Yukio Horikawa, Masakatsu Sone, and Daisuke Yabe

Introduction Carbohydrate response element-binding protein (ChREBP) is critical for regulation of fatty acid and triglyceride synthesis in the liver ( Iizuka 2017 ). ChREBP has two isoforms, ChREBP-α ( Chrebpa ) and ChREBP-β ( Chrebpb

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Kyung-Ah Kim, Sun-O Ka, Woo Sung Moon, Ho-Keun Yi, Young-Hoon Lee, Kang-Beom Kwon, Jin-Woo Park, and Byung-Hyun Park

-acclimated for 60 min and horizontal locomotor activity was quantified for 60 min. Plasma measurements Plasma triglyceride (TG) was measured using a glycerol phosphate oxidase-Trinder TG kit (Sigma). Plasma free fatty acid (FFA) and glycerol were measured using a

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Sabina Börner, Michael Derno, Sandra Hacke, Ulrike Kautzsch, Christine Schäff, Sint ThanThan, Hideto Kuwayama, Harald M Hammon, Monika Röntgen, Rosemarie Weikard, Christa Kühn, Armin Tuchscherer, and Björn Kuhla

characterized by high body fat mobilization. This suggests that, in addition to its role in preventing starvation, ghrelin exerts a prominent role in the regulation of fat metabolism. For example, feeding rumen-protected long-chain fatty acids increases the

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Prasanthi P Koganti and Vimal Selvaraj

status between the mouse and hamster adrenals, we evaluated the expression of a few core genes involved in the regulation of these processes. We found that Cpt1a , a transferase essential for mitochondrial fatty acid oxidation (FAO), was substantially

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Bettina Geidl-Flueck and Philipp A Gerber

hypothesized that an increased de novo lipogenesis after fructose intake in parallel with a decreased fatty acid oxidation leads to hepatic fat deposition. ACC, acetyl-CoA-carboxylase; ATP, adenosine triphosphate; CPT1a, carnitine palmitoyltransferase 1A; FA

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Rachel Botchlett, Shih-Lung Woo, Mengyang Liu, Ya Pei, Xin Guo, Honggui Li, and Chaodong Wu

the adult AMDR is a suggested intake of linoleic acid at 12–17 g/day and α-linolenic acid at 1.1–1.6 g/day, both of which are essential fatty acids and thus, cannot be synthesized innately but only obtained through the diet. High-fat diets (HFD

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Jose A Viscarra, Cory D Champagne, Daniel E Crocker, and Rudy M Ortiz

gluconeogenesis (the generation of glucose from non-carbohydrate substrates), and free fatty acids, which decrease insulin sensitivity by inhibiting intracellular insulin signaling and glucose uptake, are increased in the circulation, contributing to continuation