adult male CD1 mice to BPA (0, 5, 50, 500, and 5000 μg/kg per day) resulted in the accumulation of hepatic triglycerides (TGs) and cholesteryl esters (CHOL), changes in hepatic free fatty acid (FFA) composition as well as upregulation of genes involved
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Jie Wei, Xia Sun, Yajie Chen, Yuanyuan Li, Liqiong Song, Zhao Zhou, Bing Xu, Yi Lin, and Shunqing Xu
Barbara J Clark
? ? ? The thioesterase multidomain proteins STARD14 ACOT11_v2, BFIT2 Brown adipose tissue † Cytosolic c ? Fatty acid d (?) Medium chain fatty-acyl-coA hydrolysis 10 STARD15 ACOT12 Liver † Cytosolic c ? Acetyl-coA hydrolysis 11 StAR, steroidogenic acute
Blerina Kola and Márta Korbonits
intracellular Ca 2 + levels. Ghrelin has a unique fatty acid modification on its N-terminal end as a result of the activity of the ghrelin O -acyltransferase enzyme ( Yang et al . 2008 ). However, the majority of circulating ghrelin is actually lacking this
Ken Takao, Katsumi Iizuka, Yanyan Liu, Teruaki Sakurai, Sodai Kubota, Saki Kubota-Okamoto, Toshinori Imaizumi, Yoshihiro Takahashi, Yermek Rakhat, Satoko Komori, Tokuyuki Hirose, Kenta Nonomura, Takehiro Kato, Masami Mizuno, Tetsuya Suwa, Yukio Horikawa, Masakatsu Sone, and Daisuke Yabe
Introduction Carbohydrate response element-binding protein (ChREBP) is critical for regulation of fatty acid and triglyceride synthesis in the liver ( Iizuka 2017 ). ChREBP has two isoforms, ChREBP-α ( Chrebpa ) and ChREBP-β ( Chrebpb
Kyung-Ah Kim, Sun-O Ka, Woo Sung Moon, Ho-Keun Yi, Young-Hoon Lee, Kang-Beom Kwon, Jin-Woo Park, and Byung-Hyun Park
-acclimated for 60 min and horizontal locomotor activity was quantified for 60 min. Plasma measurements Plasma triglyceride (TG) was measured using a glycerol phosphate oxidase-Trinder TG kit (Sigma). Plasma free fatty acid (FFA) and glycerol were measured using a
Sabina Börner, Michael Derno, Sandra Hacke, Ulrike Kautzsch, Christine Schäff, Sint ThanThan, Hideto Kuwayama, Harald M Hammon, Monika Röntgen, Rosemarie Weikard, Christa Kühn, Armin Tuchscherer, and Björn Kuhla
characterized by high body fat mobilization. This suggests that, in addition to its role in preventing starvation, ghrelin exerts a prominent role in the regulation of fat metabolism. For example, feeding rumen-protected long-chain fatty acids increases the
Prasanthi P Koganti and Vimal Selvaraj
status between the mouse and hamster adrenals, we evaluated the expression of a few core genes involved in the regulation of these processes. We found that Cpt1a , a transferase essential for mitochondrial fatty acid oxidation (FAO), was substantially
Bettina Geidl-Flueck and Philipp A Gerber
hypothesized that an increased de novo lipogenesis after fructose intake in parallel with a decreased fatty acid oxidation leads to hepatic fat deposition. ACC, acetyl-CoA-carboxylase; ATP, adenosine triphosphate; CPT1a, carnitine palmitoyltransferase 1A; FA
Rachel Botchlett, Shih-Lung Woo, Mengyang Liu, Ya Pei, Xin Guo, Honggui Li, and Chaodong Wu
the adult AMDR is a suggested intake of linoleic acid at 12–17 g/day and α-linolenic acid at 1.1–1.6 g/day, both of which are essential fatty acids and thus, cannot be synthesized innately but only obtained through the diet. High-fat diets (HFD
Jose A Viscarra, Cory D Champagne, Daniel E Crocker, and Rudy M Ortiz
gluconeogenesis (the generation of glucose from non-carbohydrate substrates), and free fatty acids, which decrease insulin sensitivity by inhibiting intracellular insulin signaling and glucose uptake, are increased in the circulation, contributing to continuation
