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Robin Kristófi Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, Uppsala, Sweden

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Jan W Eriksson Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, Uppsala, Sweden

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group box 1; HSP60, heat shock protein 60; IFN-β, interferon-β; IL-1β, interleukin-1β; IL-6, interleukin-6; iPFK2, inducible phosphofructokinase 2; IRAK1, interleukin-1 receptor-associated kinase 1; JAK2, Janus kinase 2; JNK, c-Jun N-terminal kinase

Article Type:
Review Article
Collections:
Top-cited articles of 2023
DOI:
https://doi.org/10.1530/JOE-21-0194
Volume/Issue:
Volume 251: Issue 2
Free access
Elisabet Estil.les Laboratory of Diabetes and Experimental Endocrinology, CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Endocrine Unit (13-2), Department of Clinical Sciences, IDIBELL-University of Barcelona, Feixa Llarga s/n 08907 L'Hospitalet de Llobregat, Barcelona, Spain

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Noèlia Téllez Laboratory of Diabetes and Experimental Endocrinology, CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Endocrine Unit (13-2), Department of Clinical Sciences, IDIBELL-University of Barcelona, Feixa Llarga s/n 08907 L'Hospitalet de Llobregat, Barcelona, Spain
Laboratory of Diabetes and Experimental Endocrinology, CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Endocrine Unit (13-2), Department of Clinical Sciences, IDIBELL-University of Barcelona, Feixa Llarga s/n 08907 L'Hospitalet de Llobregat, Barcelona, Spain

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Joan Soler Laboratory of Diabetes and Experimental Endocrinology, CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Endocrine Unit (13-2), Department of Clinical Sciences, IDIBELL-University of Barcelona, Feixa Llarga s/n 08907 L'Hospitalet de Llobregat, Barcelona, Spain
Laboratory of Diabetes and Experimental Endocrinology, CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Endocrine Unit (13-2), Department of Clinical Sciences, IDIBELL-University of Barcelona, Feixa Llarga s/n 08907 L'Hospitalet de Llobregat, Barcelona, Spain
Laboratory of Diabetes and Experimental Endocrinology, CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Endocrine Unit (13-2), Department of Clinical Sciences, IDIBELL-University of Barcelona, Feixa Llarga s/n 08907 L'Hospitalet de Llobregat, Barcelona, Spain

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Eduard Montanya Laboratory of Diabetes and Experimental Endocrinology, CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Endocrine Unit (13-2), Department of Clinical Sciences, IDIBELL-University of Barcelona, Feixa Llarga s/n 08907 L'Hospitalet de Llobregat, Barcelona, Spain
Laboratory of Diabetes and Experimental Endocrinology, CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Endocrine Unit (13-2), Department of Clinical Sciences, IDIBELL-University of Barcelona, Feixa Llarga s/n 08907 L'Hospitalet de Llobregat, Barcelona, Spain
Laboratory of Diabetes and Experimental Endocrinology, CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Endocrine Unit (13-2), Department of Clinical Sciences, IDIBELL-University of Barcelona, Feixa Llarga s/n 08907 L'Hospitalet de Llobregat, Barcelona, Spain

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-Poulsen 1996 ), and recently it has also been related to the development of type 2 diabetes ( Larsen et al . 2007 ). It is well established that IL1B, alone or in combination with other pro-inflammatory cytokines interferon-γ (IFNG) and tumour necrosis factor

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-09-0047
Volume/Issue:
Volume 203: Issue 1
Free access
Xianghui Meng Chinese Medicine Hospital in Linyi City, Linyi, China

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Shuhang Xu Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China

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Guofang Chen Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China

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Michael Derwahl Division of Endocrinology, Department of Medicine, St. Hedwig Hospital, Berlin, Germany

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Chao Liu Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China

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al . 2016 a Four-month Pilot study Two matched groups of women with type 2 diabetes and untreated subclinical hypothyroidism 20 individuals The effect of metformin on serum thyrotropin was stronger in patients with interferon

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-16-0450
Volume/Issue:
Volume 233: Issue 1
Free access
Weiwei Xu Section of Endocrinology and Metabolism, Department of Medicine, Diabetes Discovery Research and Gender Medicine Laboratory, Tulane University Health Sciences Center, School of Medicine, and Southeast Louisiana Veterans Healthcare System Medical Center, New Orleans, Louisiana, USA

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Jamie Morford Section of Endocrinology and Metabolism, Department of Medicine, Diabetes Discovery Research and Gender Medicine Laboratory, Tulane University Health Sciences Center, School of Medicine, and Southeast Louisiana Veterans Healthcare System Medical Center, New Orleans, Louisiana, USA

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Franck Mauvais-Jarvis Section of Endocrinology and Metabolism, Department of Medicine, Diabetes Discovery Research and Gender Medicine Laboratory, Tulane University Health Sciences Center, School of Medicine, and Southeast Louisiana Veterans Healthcare System Medical Center, New Orleans, Louisiana, USA

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( Schulthess et al . 2009 , Nunemaker et al . 2014 ), several interferon-gamma-induced guanylate-binding proteins ( Kim et al . 2016 ), intra-islet proinflammatory cytokines and associated receptors like interleukin-1β, the interleukin 22 receptor-α1

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-18-0573
Volume/Issue:
Volume 240: Issue 3
Free access
Irina V Mikhaylova
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Tiina Jääskeläinen Department of Pediatrics, Institute of Biomedicine/Medical Biochemistry, Kuopio University and University Hospital, PO Box 1777, FI-70211 Kuopio, Finland

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Jarmo Jääskeläinen
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Jorma J Palvimo Department of Pediatrics, Institute of Biomedicine/Medical Biochemistry, Kuopio University and University Hospital, PO Box 1777, FI-70211 Kuopio, Finland

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Raimo Voutilainen
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-Lehtinen P Sahin AA Kurzrock R Talpaz M Aggarwal BB 1995 Leukemia inhibitory factor binds to human breast cancer cells and stimulates their proliferation . Journal of Interferon & Cytokine Research 15 905 – 913 . Ferrara N Winer J Henzel

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-08-0377
Volume/Issue:
Volume 199: Issue 3
Free access
Eduardo Roggero Instituto de Inmunología, Facultad de Ciencias Médicas, Santa Fé 3100, Universidad Nacional de Rosario, 2000 Rosario, Argentina
Ilex-Conicet, Instituto de Investigaciones Hematológicas, Pacheco de Melo 308, Academia Nacional de Medicina, 1425 Buenos Aires, Argentina
Department of Immunophysiology, Institute of Physiology, Medical Faculty, Deutschhausstrasse 2, Philipps University, 35037 Marburg, Germany

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Ana R Pérez Instituto de Inmunología, Facultad de Ciencias Médicas, Santa Fé 3100, Universidad Nacional de Rosario, 2000 Rosario, Argentina
Ilex-Conicet, Instituto de Investigaciones Hematológicas, Pacheco de Melo 308, Academia Nacional de Medicina, 1425 Buenos Aires, Argentina
Department of Immunophysiology, Institute of Physiology, Medical Faculty, Deutschhausstrasse 2, Philipps University, 35037 Marburg, Germany

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Maximiliano Tamae-Kakazu Instituto de Inmunología, Facultad de Ciencias Médicas, Santa Fé 3100, Universidad Nacional de Rosario, 2000 Rosario, Argentina
Ilex-Conicet, Instituto de Investigaciones Hematológicas, Pacheco de Melo 308, Academia Nacional de Medicina, 1425 Buenos Aires, Argentina
Department of Immunophysiology, Institute of Physiology, Medical Faculty, Deutschhausstrasse 2, Philipps University, 35037 Marburg, Germany

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Isabel Piazzon Instituto de Inmunología, Facultad de Ciencias Médicas, Santa Fé 3100, Universidad Nacional de Rosario, 2000 Rosario, Argentina
Ilex-Conicet, Instituto de Investigaciones Hematológicas, Pacheco de Melo 308, Academia Nacional de Medicina, 1425 Buenos Aires, Argentina
Department of Immunophysiology, Institute of Physiology, Medical Faculty, Deutschhausstrasse 2, Philipps University, 35037 Marburg, Germany

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Irene Nepomnaschy Instituto de Inmunología, Facultad de Ciencias Médicas, Santa Fé 3100, Universidad Nacional de Rosario, 2000 Rosario, Argentina
Ilex-Conicet, Instituto de Investigaciones Hematológicas, Pacheco de Melo 308, Academia Nacional de Medicina, 1425 Buenos Aires, Argentina
Department of Immunophysiology, Institute of Physiology, Medical Faculty, Deutschhausstrasse 2, Philipps University, 35037 Marburg, Germany

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Hugo O Besedovsky Instituto de Inmunología, Facultad de Ciencias Médicas, Santa Fé 3100, Universidad Nacional de Rosario, 2000 Rosario, Argentina
Ilex-Conicet, Instituto de Investigaciones Hematológicas, Pacheco de Melo 308, Academia Nacional de Medicina, 1425 Buenos Aires, Argentina
Department of Immunophysiology, Institute of Physiology, Medical Faculty, Deutschhausstrasse 2, Philipps University, 35037 Marburg, Germany

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Oscar A Bottasso Instituto de Inmunología, Facultad de Ciencias Médicas, Santa Fé 3100, Universidad Nacional de Rosario, 2000 Rosario, Argentina
Ilex-Conicet, Instituto de Investigaciones Hematológicas, Pacheco de Melo 308, Academia Nacional de Medicina, 1425 Buenos Aires, Argentina
Department of Immunophysiology, Institute of Physiology, Medical Faculty, Deutschhausstrasse 2, Philipps University, 35037 Marburg, Germany

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Adriana del Rey Instituto de Inmunología, Facultad de Ciencias Médicas, Santa Fé 3100, Universidad Nacional de Rosario, 2000 Rosario, Argentina
Ilex-Conicet, Instituto de Investigaciones Hematológicas, Pacheco de Melo 308, Academia Nacional de Medicina, 1425 Buenos Aires, Argentina
Department of Immunophysiology, Institute of Physiology, Medical Faculty, Deutschhausstrasse 2, Philipps University, 35037 Marburg, Germany

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amastigote counts in peritoneal macrophages were comparable in both strains. The main differences between infected C57Bl/6J and Balb/c mice were observed in cytokine levels. Although blood levels of tumor necrosis factor-α (TNF-α), interferon-γ (IFN

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06642
Volume/Issue:
Volume 190: Issue 2
Free access
Ángela Sánchez Instituto de Investigaciones Biomédicas ‘Alberto Sols’, Consejo Superior de Investigaciones Científicas and Universidad Autónoma de Madrid, Madrid, Spain

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Constanza Contreras-Jurado Instituto de Investigaciones Biomédicas ‘Alberto Sols’, Consejo Superior de Investigaciones Científicas and Universidad Autónoma de Madrid, Madrid, Spain
Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain

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Diego Rodríguez Instituto de Investigaciones Biomédicas ‘Alberto Sols’, Consejo Superior de Investigaciones Científicas and Universidad Autónoma de Madrid, Madrid, Spain

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Javier Regadera Department of Anatomy, Histology and Neuroscience, Universidad Autónoma de Madrid, Madrid, Spain

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Susana Alemany Instituto de Investigaciones Biomédicas ‘Alberto Sols’, Consejo Superior de Investigaciones Científicas and Universidad Autónoma de Madrid, Madrid, Spain

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Ana Aranda Instituto de Investigaciones Biomédicas ‘Alberto Sols’, Consejo Superior de Investigaciones Científicas and Universidad Autónoma de Madrid, Madrid, Spain
Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain

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) mice. (C) Total RNA was isolated from spleens of Wt ( n  = 5) and TRα1/TRβ KO mice ( n  = 6) and transcript levels for interleukin 1α (IL1α), interleukin 6 (IL6), interleukin 10 (IL10), tumor necrosis factor α (TNFα), interferon α (IFNα), interferon γ

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-19-0339
Volume/Issue:
Volume 244: Issue 1
Restricted access
Mitra Arianmanesh Division of Applied Medicine, Department of Anatomical Sciences, School of Medical Sciences, School of Veterinary Medicine and Science, UMR 1198, Institute of Medical Sciences, Centre for Reproductive Endocrinology and Medicine, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK
Division of Applied Medicine, Department of Anatomical Sciences, School of Medical Sciences, School of Veterinary Medicine and Science, UMR 1198, Institute of Medical Sciences, Centre for Reproductive Endocrinology and Medicine, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK

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Rebecca H McIntosh Division of Applied Medicine, Department of Anatomical Sciences, School of Medical Sciences, School of Veterinary Medicine and Science, UMR 1198, Institute of Medical Sciences, Centre for Reproductive Endocrinology and Medicine, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK

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Richard G Lea Division of Applied Medicine, Department of Anatomical Sciences, School of Medical Sciences, School of Veterinary Medicine and Science, UMR 1198, Institute of Medical Sciences, Centre for Reproductive Endocrinology and Medicine, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK

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Paul A Fowler Division of Applied Medicine, Department of Anatomical Sciences, School of Medical Sciences, School of Veterinary Medicine and Science, UMR 1198, Institute of Medical Sciences, Centre for Reproductive Endocrinology and Medicine, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK

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Kaïs H Al-Gubory Division of Applied Medicine, Department of Anatomical Sciences, School of Medical Sciences, School of Veterinary Medicine and Science, UMR 1198, Institute of Medical Sciences, Centre for Reproductive Endocrinology and Medicine, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK

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+ ), soluble (IDH1), guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (GNB2), apolipoprotein A-1 (APOA1) and interferon (IFN)-induced GTP-binding protein Mx1 (or myxovirus resistance protein1 (MX1))) were identified in more than a single 2DE

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-10-0336
Volume/Issue:
Volume 210: Issue 1
Free access
Rosalia C M Simmen Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

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Dustin M Brown Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

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Charles M Quick Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

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Iad Alhallak Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

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Tyler Rose Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

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Shi J Liu Department of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

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Angela S Kelley Department of Obstetrics and Gynecology, The University of Michigan Health System, Ann Arbor, Michigan, USA

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. 2016 ) presents a comprehensive description of immune-inflammation genes associated with ENDO. Interferon-γ is a key molecule in ENDO ( Mier-Cabrera et al. 2011 , Gueuvoghlanian-Silva et al. 2018 ) and in T1DM ( Driver et al. 2017 , Osum et al

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-19-0248
Volume/Issue:
Volume 243: Issue 3
Free access
Aline Cordeiro Biophysics Institute Carlos Chagas Filho, Federal University of Rio de Janeiro, Centro de Ciências da Saúde, Avenida Carlos Chagas Filho, 373, Bloco G, Cidade Universitária - Ilha do Fundão, Rio de Janeiro - RJ 21941-902, Brazil

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Luana Lopes Souza Biophysics Institute Carlos Chagas Filho, Federal University of Rio de Janeiro, Centro de Ciências da Saúde, Avenida Carlos Chagas Filho, 373, Bloco G, Cidade Universitária - Ilha do Fundão, Rio de Janeiro - RJ 21941-902, Brazil

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Marcelo Einicker-Lamas Biophysics Institute Carlos Chagas Filho, Federal University of Rio de Janeiro, Centro de Ciências da Saúde, Avenida Carlos Chagas Filho, 373, Bloco G, Cidade Universitária - Ilha do Fundão, Rio de Janeiro - RJ 21941-902, Brazil

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Carmen Cabanelas Pazos-Moura Biophysics Institute Carlos Chagas Filho, Federal University of Rio de Janeiro, Centro de Ciências da Saúde, Avenida Carlos Chagas Filho, 373, Bloco G, Cidade Universitária - Ilha do Fundão, Rio de Janeiro - RJ 21941-902, Brazil

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other kinases ( Idris et al . 2001 ). Lin et al . (1996 b ) demonstrated that thyroid hormone can potentiate interferon gamma-induced antiviral states in a PKC-dependent manner. In Hep G cells, T 3 causes a time-dependent PKC-α cytosol

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-12-0542
Volume/Issue:
Volume 216: Issue 3
Free access