RM , Levartosky D, Leszczynska-Piziak J, Yegudin J & Abramson S 1994 Nitric oxide reacts with intracellular glutathione and activates the hexose monophosphate shunt in human neutrophils: evidence for S -nitrosoglutathione as a bioactive
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R Mastrocola, F Restivo, I Vercellinatto, O Danni, E Brignardello, M Aragno, and G Boccuzzi
Rachel T Scarl, C Martin Lawrence, Hannah M Gordon, and Craig S Nunemaker
overexpression reduced rates of atherosclerosis and plaque formation in diabetic mice ( Wang et al. 2014 ), while its deficiency promoted atherosclerosis (Freyhaus et al. 2012). Similarly, STEAP4 overexpression reduced migration of neutrophil-like HL60
Clara Lefranc, Malou Friederich-Persson, Roberto Palacios-Ramirez, and Aurelie Nguyen Dinh Cat
, macrophages and neutrophils ( Elgazar-Carmon et al. 2008 , Nishimura et al. 2009 , Winer et al. 2011 , Cawthorn et al. 2012 , Talukdar et al. 2012 ). Adipocytes and immune cells produce a large number of bioactive substances (hormones, cytokines
Emilio Hirsch, Carlotta Costa, and Elisa Ciraolo
, leptin causes a delayed apoptosis of mature neutrophils in vitro , through a signaling cascade involving PI3K ( Bruno et al. 2005 ). Altogether, these indications suggest that leptin can induce PI3K signaling to influence different responses in
Geoffrey L Hammond
now known that several endogenous proteases, including neutrophil elastase ( Hammond et al. 1990 ) and chymotrypsin ( Lewis & Elder 2014 ), and a protease (LasB) produced by the opportunistic bacterial pathogen, Pseudomonas aeruginosa ( Simard et
Morag J Young, Colin D Clyne, and Karen E Chapman
-HSD1 expression in most cells and tissues; ( Sai et al. 2008 , Morgan et al. 2014 )). Whilst 11β-HSD2 is not normally expressed in immune cells, 11β-HSD1 is expressed in glucocorticoid targets, such as activated neutrophils or macrophages, where it
Mika Suzuki, Hiroshi Kobayashi, Yoshiko Tanaka, Naohiro Kanayama, and Toshihiko Terao
S, Shibata Y, Sata M, Kato S, Saito H, Hino T, Takahashi H & Tomoike H 1997 Inhibition of neutrophil elastase-induced interleukin-8 gene expression by urinary trypsin inhibitor in human bronchial epithelial cells. International Archives Allergy
Laurie Rouger, G Raphaël Denis, Souphalone Luangsay, and Marc Parmentier
cathepsin G, neutrophil elastase, and proteases of the coagulation cascade ( Wittamer et al . 2003 ). Chemerin acts via its G-protein-coupled receptor ChemR23, expressed in dendritic cells and macrophages, and displays anti-inflammatory properties
Christian Vollmer, Ingo Schwartges, Robert Behmke, Inge Bauer, and Olaf Picker
. Mythen MG Purdy G Mackie IJ McNally T Webb AR Machin SJ 1993 Postoperative multiple organ dysfunction syndrome associated with gut mucosal hypoperfusion, increased neutrophil degranulation and C1-esterase
Amy Hughes, Darling Rojas-Canales, Chris Drogemuller, Nicolas H Voelcker, Shane T Grey, and P T H Coates
multiple chemokines and acute neutrophil-dependent hepatic injury in vivo . Human Gene Therapy 10 965 – 976 . ( doi:10.1089/10430349950018364 ) Nandi SK Kundu B Basu D 2013 Protein growth factors loaded highly porous chitosan scaffold: a
