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R Mastrocola, F Restivo, I Vercellinatto, O Danni, E Brignardello, M Aragno, and G Boccuzzi

RM , Levartosky D, Leszczynska-Piziak J, Yegudin J & Abramson S 1994 Nitric oxide reacts with intracellular glutathione and activates the hexose monophosphate shunt in human neutrophils: evidence for S -nitrosoglutathione as a bioactive

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Rachel T Scarl, C Martin Lawrence, Hannah M Gordon, and Craig S Nunemaker

overexpression reduced rates of atherosclerosis and plaque formation in diabetic mice ( Wang et al. 2014 ), while its deficiency promoted atherosclerosis (Freyhaus et al. 2012). Similarly, STEAP4 overexpression reduced migration of neutrophil-like HL60

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Clara Lefranc, Malou Friederich-Persson, Roberto Palacios-Ramirez, and Aurelie Nguyen Dinh Cat

, macrophages and neutrophils ( Elgazar-Carmon et al. 2008 , Nishimura et al. 2009 , Winer et al. 2011 , Cawthorn et al. 2012 , Talukdar et al. 2012 ). Adipocytes and immune cells produce a large number of bioactive substances (hormones, cytokines

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Emilio Hirsch, Carlotta Costa, and Elisa Ciraolo

, leptin causes a delayed apoptosis of mature neutrophils in vitro , through a signaling cascade involving PI3K ( Bruno et al. 2005 ). Altogether, these indications suggest that leptin can induce PI3K signaling to influence different responses in

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Geoffrey L Hammond

now known that several endogenous proteases, including neutrophil elastase ( Hammond et al. 1990 ) and chymotrypsin ( Lewis & Elder 2014 ), and a protease (LasB) produced by the opportunistic bacterial pathogen, Pseudomonas aeruginosa ( Simard et

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Morag J Young, Colin D Clyne, and Karen E Chapman

-HSD1 expression in most cells and tissues; ( Sai et al. 2008 , Morgan et al. 2014 )). Whilst 11β-HSD2 is not normally expressed in immune cells, 11β-HSD1 is expressed in glucocorticoid targets, such as activated neutrophils or macrophages, where it

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Mika Suzuki, Hiroshi Kobayashi, Yoshiko Tanaka, Naohiro Kanayama, and Toshihiko Terao

S, Shibata Y, Sata M, Kato S, Saito H, Hino T, Takahashi H & Tomoike H 1997 Inhibition of neutrophil elastase-induced interleukin-8 gene expression by urinary trypsin inhibitor in human bronchial epithelial cells. International Archives Allergy

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Laurie Rouger, G Raphaël Denis, Souphalone Luangsay, and Marc Parmentier

cathepsin G, neutrophil elastase, and proteases of the coagulation cascade ( Wittamer et al . 2003 ). Chemerin acts via its G-protein-coupled receptor ChemR23, expressed in dendritic cells and macrophages, and displays anti-inflammatory properties

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Christian Vollmer, Ingo Schwartges, Robert Behmke, Inge Bauer, and Olaf Picker

. Mythen MG Purdy G Mackie IJ McNally T Webb AR Machin SJ 1993 Postoperative multiple organ dysfunction syndrome associated with gut mucosal hypoperfusion, increased neutrophil degranulation and C1-esterase

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Amy Hughes, Darling Rojas-Canales, Chris Drogemuller, Nicolas H Voelcker, Shane T Grey, and P T H Coates

multiple chemokines and acute neutrophil-dependent hepatic injury in vivo . Human Gene Therapy 10 965 – 976 . ( doi:10.1089/10430349950018364 ) Nandi SK Kundu B Basu D 2013 Protein growth factors loaded highly porous chitosan scaffold: a