-inducible factor (HIF)-dependent and HIF-independent pathways. The HIF-independent pathway is mainly mediated by changing protein phosphorylation status (acute) and global transcription/translation efficiency (chronic), whereas the HIF-dependent pathway is
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L Banaei-Bouchareb, M Peuchmaur, P Czernichow, and M Polak
and dendritic cells, were studied by reverse transcription and polymerase chain reaction (RT–PCR). CSF1 (colony-stimulating factor 1) and GM–CSF (granulocyte/macrophage colony-stimulating factor), which are known to be the most important growth factors
Lei Ye, Xiaoying Li, Xiangyin Kong, Weiqing Wang, Yufang Bi, Landian Hu, Bin Cui, Xi Li, and Guang Ning
defined in the human POMC promoter, domain IV (−376 to −417) had the distinctive property of being active in DMS-79 cells but not in AtT-20 cells ( Picon et al. 1995 ). It was reported that E2 transcription factor binding was required for the activity of
Y Kamei, Y Aoyama, T Fujimoto, N Kenmotsu, C Kishi, M Koushi, S Sugano, K Morohashi, R Kamiyama, and R Asakai
properties that were lost in the GC lines appears to be extremely difficult. One member of the orphan nuclear receptor subfamily, the adrenal-4 binding protein (Ad4BP), also known as steroidogenic factor-1 or NR5A1, regulates the transcription of
Marcello Maggiolini and Didier Picard
that GPR30 signaling triggers lead to the induced expression of c-fos in macrophages ( Kanda & Watanabe 2003 a ) and activation of the transcription factor CREB in keratinocytes ( Kanda & Watanabe 2003 b , 2004 ). These in turn activate the
Hyunju Chung and Seungjoon Park
transcription factor E2F1 is involved in the regulation of cell cycle regulation ( Yoshikawa 2000 ). Additionally, the activity of cyclin–CDK complex can be regulated by the inhibitory interaction with CDK inhibitors (CKIs), such as p21 CIP1 , p27 KIP1 and p57
Verónica Torres-Estay, Daniela V Carreño, Ignacio F San Francisco, Paula Sotomayor, Alejandro S Godoy, and Gary J Smith
( Wen et al . 2013 ) and that the induction of VEGF was mediated by binding of the transcription factor AR and SP1 to the core promoter region of VEGF ( Eisermann et al . 2013 ). Androgen deprivation therapy (ADT), the standard treatment for advanced
Akiko Mizokami, Satoru Mukai, Jing Gao, Tomoyo Kawakubo-Yasukochi, Takahito Otani, Hiroshi Takeuchi, Eijiro Jimi, and Masato Hirata
.01 (Student’s t test). We previously showed that GluOC activates the transcription factor CREB (cAMP response element–binding protein) and increases the expression of the transcription factor FoxO1 (forkhead box protein O1) in 3T3-L1 adipocytes
A Alidibbiat, C E Marriott, K T Scougall, S C Campbell, G C Huang, W M Macfarlane, and J A M Shaw
s at 58 °C, 45 s at 72 °C; 5 min at 72 °C). PCR cycle number was 35 for all primer pairs with the exception of Isl1 (29 cycles) and forkhead box transcription factor a2 (Foxa2; 40 cycles). PCR products were separated and visualised on 1% agarose gels
Janne Jensen, Elisabeth D Galsgaard, Allan E Karlsen, Ying C Lee, and Jens H Nielsen
hGH and cytokines on the induction of SOCS-3 mRNA expression after extended exposure. Effects of hGH and cytokines on activation of the transcription factors NFκB, STAT1 and STAT5 To determine whether activation of
