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Robin Kristófi Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, Uppsala, Sweden

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Jan W Eriksson Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, Uppsala, Sweden

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(TXNIP), which in turn leads to reduced cellular oxidative stress and so could exert a protective effect on vascular endothelium ( Li et al. 2015 ). Recent evidence also points to the role of metformin and AMPK in promoting autophagic flux to counteract

Article Type:
Review Article
Collections:
Top-cited articles of 2023
DOI:
https://doi.org/10.1530/JOE-21-0194
Volume/Issue:
Volume 251: Issue 2
Free access
Wenqi Chen Laboratory of Reproductive Biology, School of Public Health and Management, Chongqing Medical University, Chongqing, China
Joint International Research Laboratory of Reproduction & Development, Chongqing Medical University, Chongqing, China

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Siyu Lu Laboratory of Reproductive Biology, School of Public Health and Management, Chongqing Medical University, Chongqing, China
Joint International Research Laboratory of Reproduction & Development, Chongqing Medical University, Chongqing, China

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Chengshun Yang Laboratory of Reproductive Biology, School of Public Health and Management, Chongqing Medical University, Chongqing, China
Joint International Research Laboratory of Reproduction & Development, Chongqing Medical University, Chongqing, China

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Na Li Laboratory of Reproductive Biology, School of Public Health and Management, Chongqing Medical University, Chongqing, China
Joint International Research Laboratory of Reproduction & Development, Chongqing Medical University, Chongqing, China

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Xuemei Chen Laboratory of Reproductive Biology, School of Public Health and Management, Chongqing Medical University, Chongqing, China
Joint International Research Laboratory of Reproduction & Development, Chongqing Medical University, Chongqing, China

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Junlin He Laboratory of Reproductive Biology, School of Public Health and Management, Chongqing Medical University, Chongqing, China
Joint International Research Laboratory of Reproduction & Development, Chongqing Medical University, Chongqing, China

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Xueqing Liu Laboratory of Reproductive Biology, School of Public Health and Management, Chongqing Medical University, Chongqing, China
Joint International Research Laboratory of Reproduction & Development, Chongqing Medical University, Chongqing, China

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Yubin Ding Laboratory of Reproductive Biology, School of Public Health and Management, Chongqing Medical University, Chongqing, China
Joint International Research Laboratory of Reproduction & Development, Chongqing Medical University, Chongqing, China

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Chao Tong Department of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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Chuan Peng Laboratory of Maternal and Fetal Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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Chen Zhang Laboratory of Reproductive Biology, School of Public Health and Management, Chongqing Medical University, Chongqing, China
Joint International Research Laboratory of Reproduction & Development, Chongqing Medical University, Chongqing, China
Department of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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Yan Su Laboratory of Reproductive Biology, School of Public Health and Management, Chongqing Medical University, Chongqing, China
Joint International Research Laboratory of Reproduction & Development, Chongqing Medical University, Chongqing, China

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Yingxiong Wang Laboratory of Reproductive Biology, School of Public Health and Management, Chongqing Medical University, Chongqing, China
Joint International Research Laboratory of Reproduction & Development, Chongqing Medical University, Chongqing, China

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Rufei Gao Laboratory of Reproductive Biology, School of Public Health and Management, Chongqing Medical University, Chongqing, China
Joint International Research Laboratory of Reproduction & Development, Chongqing Medical University, Chongqing, China

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://doi.org/10.3109/09513590.2012.705367 ) Muniyappa R Quon MJ 2007 Insulin action and insulin resistance in vascular endothelium . Current Opinion in Clinical Nutrition and Metabolic Care 523 – 530 . ( https://doi.org/10.1097/MCO.0b013e32819f8ecd

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-19-0127
Volume/Issue:
Volume 243: Issue 2
Restricted access
Karolina Bäck Division of Cell Biology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, S-581 85 Linköping, Sweden

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Rakibul Islam Division of Cell Biology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, S-581 85 Linköping, Sweden

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Git S Johansson Division of Cell Biology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, S-581 85 Linköping, Sweden

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Simona I Chisalita Division of Cell Biology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, S-581 85 Linköping, Sweden

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Hans J Arnqvist Division of Cell Biology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, S-581 85 Linköping, Sweden

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of the endothelium ( Kim et al . 2006 , Pambianco et al . 2006 ). There is a strong association between microvascular complications and cardiomyopathy leading to heart failure ( Tarquini et al . 2010 ). Alterations in the insulin-like growth

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-12-0261
Volume/Issue:
Volume 215: Issue 1
Free access
David E Henley Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, Faculty of Medicine, Clinical Biochemistry, University of Bristol, Bristol BS1 3NY, UK
Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, Faculty of Medicine, Clinical Biochemistry, University of Bristol, Bristol BS1 3NY, UK

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Fiona Buchanan Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, Faculty of Medicine, Clinical Biochemistry, University of Bristol, Bristol BS1 3NY, UK

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Rosemary Gibson Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, Faculty of Medicine, Clinical Biochemistry, University of Bristol, Bristol BS1 3NY, UK

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Jennie A Douthwaite Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, Faculty of Medicine, Clinical Biochemistry, University of Bristol, Bristol BS1 3NY, UK

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Susan A Wood Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, Faculty of Medicine, Clinical Biochemistry, University of Bristol, Bristol BS1 3NY, UK

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Wolfram W Woltersdorf Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, Faculty of Medicine, Clinical Biochemistry, University of Bristol, Bristol BS1 3NY, UK

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James R Catterall Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, Faculty of Medicine, Clinical Biochemistry, University of Bristol, Bristol BS1 3NY, UK

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Stafford L Lightman Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, Faculty of Medicine, Clinical Biochemistry, University of Bristol, Bristol BS1 3NY, UK

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2008 ). The pulmonary apelin-producing endothelium is particularly sensitive to hypoxia ( Sheikh et al . 2008 ). Thus, upregulation of apelin in OSA may be a protective mechanism against OSA-associated hypertension and recurrent hypoxia/hypoxaemia, and

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-09-0245
Volume/Issue:
Volume 203: Issue 1
Free access
Gideon S Bevelander
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Elsa S L C Pinto Department of Animal Physiology, Centre of Marine Sciences (CCMAR), Faculty of Science, Radboud University Nijmegen, Toernooiveld 1, 6525 ED Nijmegen, The Netherlands

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Adelino V M Canario Department of Animal Physiology, Centre of Marine Sciences (CCMAR), Faculty of Science, Radboud University Nijmegen, Toernooiveld 1, 6525 ED Nijmegen, The Netherlands

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Tom Spanings
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Gert Flik
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this role in cholesterol homeostasis and efficient clearance of cholesterol ( Babiker et al . 1997 ). Further support for extrahepatic 25-hydroxylase activity came from studies that show expression of CYP27A1 in the brain, vascular endothelium, kidney

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-07-0566
Volume/Issue:
Volume 196: Issue 3
Free access
Weiwei Qin Institute of Microcirculation, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), 5 Dong Dan San Tiao, Beijing 100005, China

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Wenbao Lu Institute of Microcirculation, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), 5 Dong Dan San Tiao, Beijing 100005, China

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Hongwei Li Institute of Microcirculation, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), 5 Dong Dan San Tiao, Beijing 100005, China

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Xiaochen Yuan Institute of Microcirculation, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), 5 Dong Dan San Tiao, Beijing 100005, China

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Bingwei Li Institute of Microcirculation, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), 5 Dong Dan San Tiao, Beijing 100005, China

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Qiuju Zhang Institute of Microcirculation, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), 5 Dong Dan San Tiao, Beijing 100005, China

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Ruijuan Xiu Institute of Microcirculation, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), 5 Dong Dan San Tiao, Beijing 100005, China

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’ morphology and appeared to connect separate cells when the monolayers were confluent and were positive immunostaining for vWF, a marker for endothelium (data not shown). To investigate the effect of melatonin on expressions of MMP9, MMP2, TIMP1, and TIMP2 in

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-12-0147
Volume/Issue:
Volume 214: Issue 2
Free access
M A J Hervé INSERM U553, Institut Universitaire d’Hématologie, Hôpital Saint-Louis/Bâtiment INSERM, 1 avenue Claude Vellefaux, 75010 Paris, France
INSERM U716, Institut Universitaire d’Hématologie, Hôpital Saint-Louis/Bâtiment INSERM, 1 avenue Claude Vellefaux, 75010 Paris, France
Unité INSERM 540, Montpellier, France

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G Meduri INSERM U553, Institut Universitaire d’Hématologie, Hôpital Saint-Louis/Bâtiment INSERM, 1 avenue Claude Vellefaux, 75010 Paris, France
INSERM U716, Institut Universitaire d’Hématologie, Hôpital Saint-Louis/Bâtiment INSERM, 1 avenue Claude Vellefaux, 75010 Paris, France
Unité INSERM 540, Montpellier, France

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F G Petit INSERM U553, Institut Universitaire d’Hématologie, Hôpital Saint-Louis/Bâtiment INSERM, 1 avenue Claude Vellefaux, 75010 Paris, France
INSERM U716, Institut Universitaire d’Hématologie, Hôpital Saint-Louis/Bâtiment INSERM, 1 avenue Claude Vellefaux, 75010 Paris, France
Unité INSERM 540, Montpellier, France

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T S Domet INSERM U553, Institut Universitaire d’Hématologie, Hôpital Saint-Louis/Bâtiment INSERM, 1 avenue Claude Vellefaux, 75010 Paris, France
INSERM U716, Institut Universitaire d’Hématologie, Hôpital Saint-Louis/Bâtiment INSERM, 1 avenue Claude Vellefaux, 75010 Paris, France
Unité INSERM 540, Montpellier, France

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G Lazennec INSERM U553, Institut Universitaire d’Hématologie, Hôpital Saint-Louis/Bâtiment INSERM, 1 avenue Claude Vellefaux, 75010 Paris, France
INSERM U716, Institut Universitaire d’Hématologie, Hôpital Saint-Louis/Bâtiment INSERM, 1 avenue Claude Vellefaux, 75010 Paris, France
Unité INSERM 540, Montpellier, France

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S Mourah INSERM U553, Institut Universitaire d’Hématologie, Hôpital Saint-Louis/Bâtiment INSERM, 1 avenue Claude Vellefaux, 75010 Paris, France
INSERM U716, Institut Universitaire d’Hématologie, Hôpital Saint-Louis/Bâtiment INSERM, 1 avenue Claude Vellefaux, 75010 Paris, France
Unité INSERM 540, Montpellier, France

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M Perrot-Applanat INSERM U553, Institut Universitaire d’Hématologie, Hôpital Saint-Louis/Bâtiment INSERM, 1 avenue Claude Vellefaux, 75010 Paris, France
INSERM U716, Institut Universitaire d’Hématologie, Hôpital Saint-Louis/Bâtiment INSERM, 1 avenue Claude Vellefaux, 75010 Paris, France
Unité INSERM 540, Montpellier, France

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1993 , Shifren et al. 1996 , Bausero et al. 2000 ). The present study demonstrates a VEGF-induced up-regulation of Flk-1/KDR mRNA in endothelial cells (HUVEC), in agreement with a previous study on the capillary endothelium of bovine adrenal

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06184
Volume/Issue:
Volume 188: Issue 1
Free access
S E Ulbrich Physiology-Weihenstephan, Technical University of Munich, Alles Hörsaalgebäude, 85350 Freising, Germany
Institute of Veterinary Biochemistry, Free University of Berlin, Oertzenweg 19b, D-14163 Berlin, Germany
Institute of Molecular Animal Breeding and Biotechnology, Gene Centre of the Ludwig-Maximilians-University Munich, Munich, Germany
Institute of Veterinary Anatomy, Histology and Embryology, Ludwig-Maximilians-University Munich, Veterinaerstr. 13, 80539 Munich, Germany

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S Rehfeld Physiology-Weihenstephan, Technical University of Munich, Alles Hörsaalgebäude, 85350 Freising, Germany
Institute of Veterinary Biochemistry, Free University of Berlin, Oertzenweg 19b, D-14163 Berlin, Germany
Institute of Molecular Animal Breeding and Biotechnology, Gene Centre of the Ludwig-Maximilians-University Munich, Munich, Germany
Institute of Veterinary Anatomy, Histology and Embryology, Ludwig-Maximilians-University Munich, Veterinaerstr. 13, 80539 Munich, Germany

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S Bauersachs Physiology-Weihenstephan, Technical University of Munich, Alles Hörsaalgebäude, 85350 Freising, Germany
Institute of Veterinary Biochemistry, Free University of Berlin, Oertzenweg 19b, D-14163 Berlin, Germany
Institute of Molecular Animal Breeding and Biotechnology, Gene Centre of the Ludwig-Maximilians-University Munich, Munich, Germany
Institute of Veterinary Anatomy, Histology and Embryology, Ludwig-Maximilians-University Munich, Veterinaerstr. 13, 80539 Munich, Germany

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E Wolf Physiology-Weihenstephan, Technical University of Munich, Alles Hörsaalgebäude, 85350 Freising, Germany
Institute of Veterinary Biochemistry, Free University of Berlin, Oertzenweg 19b, D-14163 Berlin, Germany
Institute of Molecular Animal Breeding and Biotechnology, Gene Centre of the Ludwig-Maximilians-University Munich, Munich, Germany
Institute of Veterinary Anatomy, Histology and Embryology, Ludwig-Maximilians-University Munich, Veterinaerstr. 13, 80539 Munich, Germany

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R Rottmayer Physiology-Weihenstephan, Technical University of Munich, Alles Hörsaalgebäude, 85350 Freising, Germany
Institute of Veterinary Biochemistry, Free University of Berlin, Oertzenweg 19b, D-14163 Berlin, Germany
Institute of Molecular Animal Breeding and Biotechnology, Gene Centre of the Ludwig-Maximilians-University Munich, Munich, Germany
Institute of Veterinary Anatomy, Histology and Embryology, Ludwig-Maximilians-University Munich, Veterinaerstr. 13, 80539 Munich, Germany

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S Hiendleder Physiology-Weihenstephan, Technical University of Munich, Alles Hörsaalgebäude, 85350 Freising, Germany
Institute of Veterinary Biochemistry, Free University of Berlin, Oertzenweg 19b, D-14163 Berlin, Germany
Institute of Molecular Animal Breeding and Biotechnology, Gene Centre of the Ludwig-Maximilians-University Munich, Munich, Germany
Institute of Veterinary Anatomy, Histology and Embryology, Ludwig-Maximilians-University Munich, Veterinaerstr. 13, 80539 Munich, Germany

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M Vermehren Physiology-Weihenstephan, Technical University of Munich, Alles Hörsaalgebäude, 85350 Freising, Germany
Institute of Veterinary Biochemistry, Free University of Berlin, Oertzenweg 19b, D-14163 Berlin, Germany
Institute of Molecular Animal Breeding and Biotechnology, Gene Centre of the Ludwig-Maximilians-University Munich, Munich, Germany
Institute of Veterinary Anatomy, Histology and Embryology, Ludwig-Maximilians-University Munich, Veterinaerstr. 13, 80539 Munich, Germany

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F Sinowatz Physiology-Weihenstephan, Technical University of Munich, Alles Hörsaalgebäude, 85350 Freising, Germany
Institute of Veterinary Biochemistry, Free University of Berlin, Oertzenweg 19b, D-14163 Berlin, Germany
Institute of Molecular Animal Breeding and Biotechnology, Gene Centre of the Ludwig-Maximilians-University Munich, Munich, Germany
Institute of Veterinary Anatomy, Histology and Embryology, Ludwig-Maximilians-University Munich, Veterinaerstr. 13, 80539 Munich, Germany

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H H D Meyer Physiology-Weihenstephan, Technical University of Munich, Alles Hörsaalgebäude, 85350 Freising, Germany
Institute of Veterinary Biochemistry, Free University of Berlin, Oertzenweg 19b, D-14163 Berlin, Germany
Institute of Molecular Animal Breeding and Biotechnology, Gene Centre of the Ludwig-Maximilians-University Munich, Munich, Germany
Institute of Veterinary Anatomy, Histology and Embryology, Ludwig-Maximilians-University Munich, Veterinaerstr. 13, 80539 Munich, Germany

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R Einspanier Physiology-Weihenstephan, Technical University of Munich, Alles Hörsaalgebäude, 85350 Freising, Germany
Institute of Veterinary Biochemistry, Free University of Berlin, Oertzenweg 19b, D-14163 Berlin, Germany
Institute of Molecular Animal Breeding and Biotechnology, Gene Centre of the Ludwig-Maximilians-University Munich, Munich, Germany
Institute of Veterinary Anatomy, Histology and Embryology, Ludwig-Maximilians-University Munich, Veterinaerstr. 13, 80539 Munich, Germany

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separate genes with different molecular weight but apparently similar molecular structure, have been described: neuronal NOS (nNOS) in the brain and peripheral nervous system; endothelial NOS (eNOS) as a constitutive NOS mainly in the endothelium; and

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06526
Volume/Issue:
Volume 188: Issue 2
Free access
John W Funder Hudson Institute, Clayton, Australia
Monash University, Clayton, Australia

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Maria-Christina Zennaro Inserm, UMRS_970, Paris Cardiovascular Research Center, Paris, France
Université Paris Descartes, Sorbonne Paris Cité, Paris, France
Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Service de Génétique, Paris, France

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(which, incidentally, is also the case for cortisol-occupied MR in other non-protected tissues). From the brain to the blood vessels. Although blood vessels are clearly not classical epithelia, both endothelium and smooth muscle cells express the

Article Type:
Editorial
DOI:
https://doi.org/10.1530/JOE-17-0264
Volume/Issue:
Volume 234: Issue 1
Free access
James I Raeside Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada

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Heather L Christie Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada

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.1126/scisignal.aad8170 ) Menazza S Sun J Appachi S Chambliss KL Kim SH Aponte A Khan S Katzenellenbogen JA Katzenellenbogen BS Shaul PW 2017 Non-nuclear estrogen receptor alpha activation in endothelium reduces cardiac ischemia

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-22-0177
Volume/Issue:
Volume 255: Issue 2
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