Search Results
Brenna Osborne
Brenna Osborne
Diabetes and Metabolism Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
Department of Pharmacology, School of Biomedical Sciences, UNSW Sydney, New South Wales, Australia
Department of Cellular and Molecular Medicine, Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Search for other papers by Brenna Osborne in
Google Scholar
PubMed
Department of Pharmacology, School of Biomedical Sciences, UNSW Sydney, New South Wales, Australia
Department of Cellular and Molecular Medicine, Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Search for other papers by Brenna Osborne in
Google Scholar
PubMed
Lauren E Wright
Lauren E Wright
Diabetes and Metabolism Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
Search for other papers by Lauren E Wright in
Google Scholar
PubMed
Search for other papers by Lauren E Wright in
Google Scholar
PubMed
Amanda E Brandon
Amanda E Brandon
Diabetes and Metabolism Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
Charles Perkins Centre, University of Sydney, New South Wales, Australia
Search for other papers by Amanda E Brandon in
Google Scholar
PubMed
Charles Perkins Centre, University of Sydney, New South Wales, Australia
Search for other papers by Amanda E Brandon in
Google Scholar
PubMed
Ella Stuart
Ella Stuart
Diabetes and Metabolism Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
Search for other papers by Ella Stuart in
Google Scholar
PubMed
Search for other papers by Ella Stuart in
Google Scholar
PubMed
Lewin Small
Lewin Small
Diabetes and Metabolism Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
Search for other papers by Lewin Small in
Google Scholar
PubMed
Search for other papers by Lewin Small in
Google Scholar
PubMed
Joris Hoeks
Joris Hoeks
NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, the Netherlands
Search for other papers by Joris Hoeks in
Google Scholar
PubMed
Search for other papers by Joris Hoeks in
Google Scholar
PubMed
Patrick Schrauwen
Patrick Schrauwen
NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, the Netherlands
Search for other papers by Patrick Schrauwen in
Google Scholar
PubMed
Search for other papers by Patrick Schrauwen in
Google Scholar
PubMed
David A Sinclair
David A Sinclair
Department of Genetics, Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School, Boston, Massachusetts, USA
Search for other papers by David A Sinclair in
Google Scholar
PubMed
Search for other papers by David A Sinclair in
Google Scholar
PubMed
Magdalene K Montgomery
Magdalene K Montgomery
Diabetes and Metabolism Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
Department of Anatomy & Physiology, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Victoria, Australia
Search for other papers by Magdalene K Montgomery in
Google Scholar
PubMed
Department of Anatomy & Physiology, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Victoria, Australia
Search for other papers by Magdalene K Montgomery in
Google Scholar
PubMed
Gregory J Cooney
Gregory J Cooney
Diabetes and Metabolism Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
Charles Perkins Centre, University of Sydney, New South Wales, Australia
Search for other papers by Gregory J Cooney in
Google Scholar
PubMed
Charles Perkins Centre, University of Sydney, New South Wales, Australia
Search for other papers by Gregory J Cooney in
Google Scholar
PubMed
Nigel Turner
Nigel Turner
Diabetes and Metabolism Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
Department of Pharmacology, School of Biomedical Sciences, UNSW Sydney, New South Wales, Australia
Cellular Bioenergetics Laboratory, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia
Search for other papers by Nigel Turner in
Google Scholar
PubMed
Department of Pharmacology, School of Biomedical Sciences, UNSW Sydney, New South Wales, Australia
Cellular Bioenergetics Laboratory, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia
Search for other papers by Nigel Turner in
Google Scholar
PubMed
number of rats used across all studies n = 38). Supplementary Fig. 1 (see section on supplementary materials given at the end of this article) describes the animal cohorts and exclusion criteria for the rat cohorts used in this study. SIRT3
Dan-Dan Feng
Dan-Dan Feng
Department of Physiology, Prince Henry's Institute of Medical Research, Xiangya Medical School, Central South University, Changsha, 410078 People's Republic of China
Department of Physiology, Prince Henry's Institute of Medical Research, Xiangya Medical School, Central South University, Changsha, 410078 People's Republic of China
Search for other papers by Dan-Dan Feng in
Google Scholar
PubMed
Department of Physiology, Prince Henry's Institute of Medical Research, Xiangya Medical School, Central South University, Changsha, 410078 People's Republic of China
Search for other papers by Dan-Dan Feng in
Google Scholar
PubMed
Yu-Feng Zhao
Yu-Feng Zhao
Department of Physiology, Prince Henry's Institute of Medical Research, Xiangya Medical School, Central South University, Changsha, 410078 People's Republic of China
Search for other papers by Yu-Feng Zhao in
Google Scholar
PubMed
Search for other papers by Yu-Feng Zhao in
Google Scholar
PubMed
Zi-Qiang Luo
Zi-Qiang Luo
Department of Physiology, Prince Henry's Institute of Medical Research, Xiangya Medical School, Central South University, Changsha, 410078 People's Republic of China
Search for other papers by Zi-Qiang Luo in
Google Scholar
PubMed
Search for other papers by Zi-Qiang Luo in
Google Scholar
PubMed
Damien J Keating
Damien J Keating
Department of Physiology, Prince Henry's Institute of Medical Research, Xiangya Medical School, Central South University, Changsha, 410078 People's Republic of China
Search for other papers by Damien J Keating in
Google Scholar
PubMed
Search for other papers by Damien J Keating in
Google Scholar
PubMed
Chen Chen
Chen Chen
Department of Physiology, Prince Henry's Institute of Medical Research, Xiangya Medical School, Central South University, Changsha, 410078 People's Republic of China
Search for other papers by Chen Chen in
Google Scholar
PubMed
Search for other papers by Chen Chen in
Google Scholar
PubMed
from Thermo Electron (Melbourne, VIC, Australia). Preparation and culture of rat pancreatic β-cells Pancreatic islets were isolated from 10 to 12 week-old male Sprague–Dawley rats as previously described ( Zhao et al . 2005 ). Briefly, rats
Takuya Yoshino
Takuya Yoshino
Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine, 3-25-8, Nishi-Shinbashi, Minato-ku, Tokyo 105-8461, Japan
Search for other papers by Takuya Yoshino in
Google Scholar
PubMed
Search for other papers by Takuya Yoshino in
Google Scholar
PubMed
Tomohisa Nagoshi
Tomohisa Nagoshi
Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine, 3-25-8, Nishi-Shinbashi, Minato-ku, Tokyo 105-8461, Japan
Search for other papers by Tomohisa Nagoshi in
Google Scholar
PubMed
Search for other papers by Tomohisa Nagoshi in
Google Scholar
PubMed
Ryuko Anzawa
Ryuko Anzawa
Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine, 3-25-8, Nishi-Shinbashi, Minato-ku, Tokyo 105-8461, Japan
Search for other papers by Ryuko Anzawa in
Google Scholar
PubMed
Search for other papers by Ryuko Anzawa in
Google Scholar
PubMed
Yusuke Kashiwagi
Yusuke Kashiwagi
Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine, 3-25-8, Nishi-Shinbashi, Minato-ku, Tokyo 105-8461, Japan
Search for other papers by Yusuke Kashiwagi in
Google Scholar
PubMed
Search for other papers by Yusuke Kashiwagi in
Google Scholar
PubMed
Keiichi Ito
Keiichi Ito
Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine, 3-25-8, Nishi-Shinbashi, Minato-ku, Tokyo 105-8461, Japan
Search for other papers by Keiichi Ito in
Google Scholar
PubMed
Search for other papers by Keiichi Ito in
Google Scholar
PubMed
Daisuke Katoh
Daisuke Katoh
Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine, 3-25-8, Nishi-Shinbashi, Minato-ku, Tokyo 105-8461, Japan
Search for other papers by Daisuke Katoh in
Google Scholar
PubMed
Search for other papers by Daisuke Katoh in
Google Scholar
PubMed
Masami Fujisaki
Masami Fujisaki
Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine, 3-25-8, Nishi-Shinbashi, Minato-ku, Tokyo 105-8461, Japan
Search for other papers by Masami Fujisaki in
Google Scholar
PubMed
Search for other papers by Masami Fujisaki in
Google Scholar
PubMed
Yosuke Kayama
Yosuke Kayama
Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine, 3-25-8, Nishi-Shinbashi, Minato-ku, Tokyo 105-8461, Japan
Search for other papers by Yosuke Kayama in
Google Scholar
PubMed
Search for other papers by Yosuke Kayama in
Google Scholar
PubMed
Taro Date
Taro Date
Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine, 3-25-8, Nishi-Shinbashi, Minato-ku, Tokyo 105-8461, Japan
Search for other papers by Taro Date in
Google Scholar
PubMed
Search for other papers by Taro Date in
Google Scholar
PubMed
Kenichi Hongo
Kenichi Hongo
Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine, 3-25-8, Nishi-Shinbashi, Minato-ku, Tokyo 105-8461, Japan
Search for other papers by Kenichi Hongo in
Google Scholar
PubMed
Search for other papers by Kenichi Hongo in
Google Scholar
PubMed
Michihiro Yoshimura
Michihiro Yoshimura
Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine, 3-25-8, Nishi-Shinbashi, Minato-ku, Tokyo 105-8461, Japan
Search for other papers by Michihiro Yoshimura in
Google Scholar
PubMed
Search for other papers by Michihiro Yoshimura in
Google Scholar
PubMed
inotropic effects in the heart ( Barbato et al . 2002 , 2004 , Chai et al . 2005 , 2006 , 2010 ). Moreover, we recently reported that aldosterone has favorable effects on cardiomyocytes during the early phase in an in vitro model of neonatal rat
C. Pihoker
C. Pihoker
Search for other papers by C. Pihoker in
Google Scholar
PubMed
Search for other papers by C. Pihoker in
Google Scholar
PubMed
M. C. Robertson
M. C. Robertson
Search for other papers by M. C. Robertson in
Google Scholar
PubMed
Search for other papers by M. C. Robertson in
Google Scholar
PubMed
M. Freemark
M. Freemark
Search for other papers by M. Freemark in
Google Scholar
PubMed
Search for other papers by M. Freemark in
Google Scholar
PubMed
ABSTRACT
Recent findings suggest that placental lactogen has a role in the regulation of hypothalamic function during pregnancy. To explore the mechanisms by which placental hormones may exert effects in the maternal central nervous system, we have examined the binding of rat placental lactogen-I (rPL-I) to brain slices from pregnant rats at mid- and late gestation. The binding of rPL-I to maternal rat brain was compared with that of human GH (hGH). Radiolabelled rPL-I bound specifically to ependymal cells of the choroid plexus in the lateral ventricles and in the roof of the third ventricle. The binding of 125I-labelled rPL-I was inhibited by unlabelled rPL-I, hGH or rat prolactin but not by rat GH, indicating that rPL-I and rat prolactin interact with a common binding site in maternal rat brain. Radiolabelled hGH bound to the choroid plexus and to ependymal cells lining the third ventricle in the region of the arcuate nucleus. In addition, hGH bound specifically to the ventromedial nuclei and to the medial preoptic area of the hypothalamus. The binding of radiolabelled hGH to all brain regions was inhibited by unlabelled rPL-I as well as hGH, indicating that rPL-I competes for lactogenic binding sites in the hypothalamus as well as the choroid plexus of the pregnant rat. These findings suggest potential mechanisms by which placental hormones may exert direct effects on the maternal central nervous system during pregnancy. The precise functions and roles of the PL-I binding sites in maternal choroid plexus and hypothalamus remain to be explored.
Journal of Endocrinology (1993) 139, 235–242
Xinrong Zhou
Xinrong Zhou
Department of Endocrinology, Key Laboratory of Systems Biology, Pathology Core Facility Institute, Clinical Medical College of Yangzhou University, Jiangsu University, Sherman College of Chiropractic, Tongji Hospital, Wuhan 430030, China
Search for other papers by Xinrong Zhou in
Google Scholar
PubMed
Search for other papers by Xinrong Zhou in
Google Scholar
PubMed
Bangguo Qian
Bangguo Qian
Department of Endocrinology, Key Laboratory of Systems Biology, Pathology Core Facility Institute, Clinical Medical College of Yangzhou University, Jiangsu University, Sherman College of Chiropractic, Tongji Hospital, Wuhan 430030, China
Department of Endocrinology, Key Laboratory of Systems Biology, Pathology Core Facility Institute, Clinical Medical College of Yangzhou University, Jiangsu University, Sherman College of Chiropractic, Tongji Hospital, Wuhan 430030, China
Search for other papers by Bangguo Qian in
Google Scholar
PubMed
Department of Endocrinology, Key Laboratory of Systems Biology, Pathology Core Facility Institute, Clinical Medical College of Yangzhou University, Jiangsu University, Sherman College of Chiropractic, Tongji Hospital, Wuhan 430030, China
Search for other papers by Bangguo Qian in
Google Scholar
PubMed
Ning Ji
Ning Ji
Department of Endocrinology, Key Laboratory of Systems Biology, Pathology Core Facility Institute, Clinical Medical College of Yangzhou University, Jiangsu University, Sherman College of Chiropractic, Tongji Hospital, Wuhan 430030, China
Department of Endocrinology, Key Laboratory of Systems Biology, Pathology Core Facility Institute, Clinical Medical College of Yangzhou University, Jiangsu University, Sherman College of Chiropractic, Tongji Hospital, Wuhan 430030, China
Search for other papers by Ning Ji in
Google Scholar
PubMed
Department of Endocrinology, Key Laboratory of Systems Biology, Pathology Core Facility Institute, Clinical Medical College of Yangzhou University, Jiangsu University, Sherman College of Chiropractic, Tongji Hospital, Wuhan 430030, China
Search for other papers by Ning Ji in
Google Scholar
PubMed
Conghui Lui
Conghui Lui
Department of Endocrinology, Key Laboratory of Systems Biology, Pathology Core Facility Institute, Clinical Medical College of Yangzhou University, Jiangsu University, Sherman College of Chiropractic, Tongji Hospital, Wuhan 430030, China
Search for other papers by Conghui Lui in
Google Scholar
PubMed
Search for other papers by Conghui Lui in
Google Scholar
PubMed
Zhiyuan Liu
Zhiyuan Liu
Department of Endocrinology, Key Laboratory of Systems Biology, Pathology Core Facility Institute, Clinical Medical College of Yangzhou University, Jiangsu University, Sherman College of Chiropractic, Tongji Hospital, Wuhan 430030, China
Search for other papers by Zhiyuan Liu in
Google Scholar
PubMed
Search for other papers by Zhiyuan Liu in
Google Scholar
PubMed
Bing Li
Bing Li
Department of Endocrinology, Key Laboratory of Systems Biology, Pathology Core Facility Institute, Clinical Medical College of Yangzhou University, Jiangsu University, Sherman College of Chiropractic, Tongji Hospital, Wuhan 430030, China
Search for other papers by Bing Li in
Google Scholar
PubMed
Search for other papers by Bing Li in
Google Scholar
PubMed
Huarong Zhou
Huarong Zhou
Department of Endocrinology, Key Laboratory of Systems Biology, Pathology Core Facility Institute, Clinical Medical College of Yangzhou University, Jiangsu University, Sherman College of Chiropractic, Tongji Hospital, Wuhan 430030, China
Department of Endocrinology, Key Laboratory of Systems Biology, Pathology Core Facility Institute, Clinical Medical College of Yangzhou University, Jiangsu University, Sherman College of Chiropractic, Tongji Hospital, Wuhan 430030, China
Department of Endocrinology, Key Laboratory of Systems Biology, Pathology Core Facility Institute, Clinical Medical College of Yangzhou University, Jiangsu University, Sherman College of Chiropractic, Tongji Hospital, Wuhan 430030, China
Search for other papers by Huarong Zhou in
Google Scholar
PubMed
Department of Endocrinology, Key Laboratory of Systems Biology, Pathology Core Facility Institute, Clinical Medical College of Yangzhou University, Jiangsu University, Sherman College of Chiropractic, Tongji Hospital, Wuhan 430030, China
Department of Endocrinology, Key Laboratory of Systems Biology, Pathology Core Facility Institute, Clinical Medical College of Yangzhou University, Jiangsu University, Sherman College of Chiropractic, Tongji Hospital, Wuhan 430030, China
Search for other papers by Huarong Zhou in
Google Scholar
PubMed
Caifeng Yan
Caifeng Yan
Department of Endocrinology, Key Laboratory of Systems Biology, Pathology Core Facility Institute, Clinical Medical College of Yangzhou University, Jiangsu University, Sherman College of Chiropractic, Tongji Hospital, Wuhan 430030, China
Search for other papers by Caifeng Yan in
Google Scholar
PubMed
Search for other papers by Caifeng Yan in
Google Scholar
PubMed
. Progressive β-cell failure, which is characteristic of longstanding T2DM, presumably rendered the pathology irreversible in these cases. Results from non-obese Goto-Kakizaki (GK) and streptozotocin (STZ)-treated T2DM rat models undergoing ileal transposition
Marion Walser
Marion Walser
Department of Internal Medicine, Institute of Medicine, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Search for other papers by Marion Walser in
Google Scholar
PubMed
Search for other papers by Marion Walser in
Google Scholar
PubMed
Linus Schiöler
Linus Schiöler
Department for Public Health and Community Medicine, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Search for other papers by Linus Schiöler in
Google Scholar
PubMed
Search for other papers by Linus Schiöler in
Google Scholar
PubMed
Jan Oscarsson
Jan Oscarsson
AstraZeneca Gothenburg, Mölndal, Sweden
Search for other papers by Jan Oscarsson in
Google Scholar
PubMed
Search for other papers by Jan Oscarsson in
Google Scholar
PubMed
Maria A I Åberg
Maria A I Åberg
Department of Primary Health Care, Institute of Medicine, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Search for other papers by Maria A I Åberg in
Google Scholar
PubMed
Search for other papers by Maria A I Åberg in
Google Scholar
PubMed
Ruth Wickelgren
Ruth Wickelgren
Department of Clinical Chemistry and Transfusion Medicine, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Search for other papers by Ruth Wickelgren in
Google Scholar
PubMed
Search for other papers by Ruth Wickelgren in
Google Scholar
PubMed
Johan Svensson
Johan Svensson
Department of Internal Medicine, Institute of Medicine, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Search for other papers by Johan Svensson in
Google Scholar
PubMed
Search for other papers by Johan Svensson in
Google Scholar
PubMed
Jörgen Isgaard
Jörgen Isgaard
Department of Internal Medicine, Institute of Medicine, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Search for other papers by Jörgen Isgaard in
Google Scholar
PubMed
Search for other papers by Jörgen Isgaard in
Google Scholar
PubMed
N David Åberg
N David Åberg
Department of Internal Medicine, Institute of Medicine, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Search for other papers by N David Åberg in
Google Scholar
PubMed
Search for other papers by N David Åberg in
Google Scholar
PubMed
whether the mode of GH treatment affects the female rat brain. By analogy with the different effects seen in the periphery, our hypothesis was that different modes of GH administrations, mimicking the specific secretion patterns in males and females, might
María Victoria Zanardi
María Victoria Zanardi
Instituto de Salud y Ambiente del Litoral (ISAL), Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Santa Fe, Argentina
Cátedra de Fisiología Humana, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe, Argentina
Faculty of Biology, Institute of Zoology, Technische Universität Dresden, Dresden, Germany
Search for other papers by María Victoria Zanardi in
Google Scholar
PubMed
Cátedra de Fisiología Humana, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe, Argentina
Faculty of Biology, Institute of Zoology, Technische Universität Dresden, Dresden, Germany
Search for other papers by María Victoria Zanardi in
Google Scholar
PubMed
María Paula Gastiazoro
María Paula Gastiazoro
Instituto de Salud y Ambiente del Litoral (ISAL), Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Santa Fe, Argentina
Cátedra de Fisiología Humana, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe, Argentina
Search for other papers by María Paula Gastiazoro in
Google Scholar
PubMed
Cátedra de Fisiología Humana, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe, Argentina
Search for other papers by María Paula Gastiazoro in
Google Scholar
PubMed
María Florencia Rossetti
María Florencia Rossetti
Instituto de Salud y Ambiente del Litoral (ISAL), Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Santa Fe, Argentina
Departamento de Bioquímica Clínica y Cuantitativa, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe, Argentina
Search for other papers by María Florencia Rossetti in
Google Scholar
PubMed
Departamento de Bioquímica Clínica y Cuantitativa, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe, Argentina
Search for other papers by María Florencia Rossetti in
Google Scholar
PubMed
Florencia Doná
Florencia Doná
Instituto de Salud y Ambiente del Litoral (ISAL), Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Santa Fe, Argentina
Search for other papers by Florencia Doná in
Google Scholar
PubMed
Search for other papers by Florencia Doná in
Google Scholar
PubMed
Gisela Paola Lazzarino
Gisela Paola Lazzarino
Instituto de Salud y Ambiente del Litoral (ISAL), Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Santa Fe, Argentina
Departamento de Bioquímica Clínica y Cuantitativa, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe, Argentina
Search for other papers by Gisela Paola Lazzarino in
Google Scholar
PubMed
Departamento de Bioquímica Clínica y Cuantitativa, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe, Argentina
Search for other papers by Gisela Paola Lazzarino in
Google Scholar
PubMed
Oliver Zierau
Oliver Zierau
Faculty of Biology, Institute of Zoology, Technische Universität Dresden, Dresden, Germany
Search for other papers by Oliver Zierau in
Google Scholar
PubMed
Search for other papers by Oliver Zierau in
Google Scholar
PubMed
Jorgelina Varayoud
Jorgelina Varayoud
Instituto de Salud y Ambiente del Litoral (ISAL), Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Santa Fe, Argentina
Cátedra de Fisiología Humana, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe, Argentina
Search for other papers by Jorgelina Varayoud in
Google Scholar
PubMed
Cátedra de Fisiología Humana, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe, Argentina
Search for other papers by Jorgelina Varayoud in
Google Scholar
PubMed
Milena Durando
Milena Durando
Instituto de Salud y Ambiente del Litoral (ISAL), Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Santa Fe, Argentina
Cátedra de Fisiología Humana, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe, Argentina
Search for other papers by Milena Durando in
Google Scholar
PubMed
Cátedra de Fisiología Humana, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe, Argentina
Search for other papers by Milena Durando in
Google Scholar
PubMed
postnatal day (PND)21 up to PND140 ( Gastiazoro et al. 2018 ). In the present study, our hypothesis was that GBH exacerbates the effects of CAF diet on the rat uterus. Therefore, we proposed to evaluate the effects of the addition of a subchronic low dose
E Kim
E Kim
Department of Pharmacology, Kyunghee University School of Medicine and Institute for Basic Medical Sciences, Seoul 130-701, Korea
Department of Medicine, University of Illinois at Chicago and Jesse Brown VA Medical Center, Research and Development, Chicago, Illinois 60612, USA
Search for other papers by E Kim in
Google Scholar
PubMed
Department of Medicine, University of Illinois at Chicago and Jesse Brown VA Medical Center, Research and Development, Chicago, Illinois 60612, USA
Search for other papers by E Kim in
Google Scholar
PubMed
S Sohn
S Sohn
Department of Pharmacology, Kyunghee University School of Medicine and Institute for Basic Medical Sciences, Seoul 130-701, Korea
Department of Medicine, University of Illinois at Chicago and Jesse Brown VA Medical Center, Research and Development, Chicago, Illinois 60612, USA
Search for other papers by S Sohn in
Google Scholar
PubMed
Department of Medicine, University of Illinois at Chicago and Jesse Brown VA Medical Center, Research and Development, Chicago, Illinois 60612, USA
Search for other papers by S Sohn in
Google Scholar
PubMed
M Lee
M Lee
Department of Pharmacology, Kyunghee University School of Medicine and Institute for Basic Medical Sciences, Seoul 130-701, Korea
Department of Medicine, University of Illinois at Chicago and Jesse Brown VA Medical Center, Research and Development, Chicago, Illinois 60612, USA
Search for other papers by M Lee in
Google Scholar
PubMed
Department of Medicine, University of Illinois at Chicago and Jesse Brown VA Medical Center, Research and Development, Chicago, Illinois 60612, USA
Search for other papers by M Lee in
Google Scholar
PubMed
J Jung
J Jung
Department of Pharmacology, Kyunghee University School of Medicine and Institute for Basic Medical Sciences, Seoul 130-701, Korea
Department of Medicine, University of Illinois at Chicago and Jesse Brown VA Medical Center, Research and Development, Chicago, Illinois 60612, USA
Search for other papers by J Jung in
Google Scholar
PubMed
Department of Medicine, University of Illinois at Chicago and Jesse Brown VA Medical Center, Research and Development, Chicago, Illinois 60612, USA
Search for other papers by J Jung in
Google Scholar
PubMed
R D Kineman
R D Kineman
Department of Pharmacology, Kyunghee University School of Medicine and Institute for Basic Medical Sciences, Seoul 130-701, Korea
Department of Medicine, University of Illinois at Chicago and Jesse Brown VA Medical Center, Research and Development, Chicago, Illinois 60612, USA
Search for other papers by R D Kineman in
Google Scholar
PubMed
Department of Medicine, University of Illinois at Chicago and Jesse Brown VA Medical Center, Research and Development, Chicago, Illinois 60612, USA
Search for other papers by R D Kineman in
Google Scholar
PubMed
S Park
S Park
Department of Pharmacology, Kyunghee University School of Medicine and Institute for Basic Medical Sciences, Seoul 130-701, Korea
Department of Medicine, University of Illinois at Chicago and Jesse Brown VA Medical Center, Research and Development, Chicago, Illinois 60612, USA
Search for other papers by S Park in
Google Scholar
PubMed
Department of Medicine, University of Illinois at Chicago and Jesse Brown VA Medical Center, Research and Development, Chicago, Illinois 60612, USA
Search for other papers by S Park in
Google Scholar
PubMed
-treated rat is more sensitive to the stimulatory actions of GHRH ( Sheppard et al. 1989 a , 1989 b ) and GH secretagogue (GHS) receptor (GHS-R) agonists (ipamorelin; Johansen et al. 2003 ) and less sensitive to the inhibitory actions of somatostatin
Christianne M A Reijnders
Christianne M A Reijnders
Departments of Endocrinology and
Clinical Chemistry, VU University Medical Center, De Boelelaan 1117, brug 124, PO Box 7057, 1081 HV Amsterdam, The Netherlands
Search for other papers by Christianne M A Reijnders in
Google Scholar
PubMed
Clinical Chemistry, VU University Medical Center, De Boelelaan 1117, brug 124, PO Box 7057, 1081 HV Amsterdam, The Netherlands
Search for other papers by Christianne M A Reijnders in
Google Scholar
PubMed
Nathalie Bravenboer
Nathalie Bravenboer
Departments of Endocrinology and
Clinical Chemistry, VU University Medical Center, De Boelelaan 1117, brug 124, PO Box 7057, 1081 HV Amsterdam, The Netherlands
Search for other papers by Nathalie Bravenboer in
Google Scholar
PubMed
Clinical Chemistry, VU University Medical Center, De Boelelaan 1117, brug 124, PO Box 7057, 1081 HV Amsterdam, The Netherlands
Search for other papers by Nathalie Bravenboer in
Google Scholar
PubMed
Annechien M Tromp
Annechien M Tromp
Departments of Endocrinology and
Clinical Chemistry, VU University Medical Center, De Boelelaan 1117, brug 124, PO Box 7057, 1081 HV Amsterdam, The Netherlands
Search for other papers by Annechien M Tromp in
Google Scholar
PubMed
Clinical Chemistry, VU University Medical Center, De Boelelaan 1117, brug 124, PO Box 7057, 1081 HV Amsterdam, The Netherlands
Search for other papers by Annechien M Tromp in
Google Scholar
PubMed
Marinus A Blankenstein
Marinus A Blankenstein
Departments of Endocrinology and
Clinical Chemistry, VU University Medical Center, De Boelelaan 1117, brug 124, PO Box 7057, 1081 HV Amsterdam, The Netherlands
Search for other papers by Marinus A Blankenstein in
Google Scholar
PubMed
Clinical Chemistry, VU University Medical Center, De Boelelaan 1117, brug 124, PO Box 7057, 1081 HV Amsterdam, The Netherlands
Search for other papers by Marinus A Blankenstein in
Google Scholar
PubMed
Paul Lips
Paul Lips
Departments of Endocrinology and
Clinical Chemistry, VU University Medical Center, De Boelelaan 1117, brug 124, PO Box 7057, 1081 HV Amsterdam, The Netherlands
Search for other papers by Paul Lips in
Google Scholar
PubMed
Clinical Chemistry, VU University Medical Center, De Boelelaan 1117, brug 124, PO Box 7057, 1081 HV Amsterdam, The Netherlands
Search for other papers by Paul Lips in
Google Scholar
PubMed
trabecular surfaces and in osteocytes of the diaphysial cortex (cortical and trabecular osteocytes) of rat caudal vertebrae within 6 h after a single loading session ( Lean et al. 1995 ). The aim of this study was to characterize the role of IGF
Koichiro Komatsu
Koichiro Komatsu
Departments of Pharmacology, Orthodontics, Transcriptome Research Group, Department of Developmental Biology of Hard Tissue, Department of Molecular Pharmacology, School of Dental Medicine, Tsurumi University, 2‐1‐3 Tsurumi, Tsurumi‐ku, Yokohama 230-8501, Japan
Search for other papers by Koichiro Komatsu in
Google Scholar
PubMed
Search for other papers by Koichiro Komatsu in
Google Scholar
PubMed
Akemi Shimada
Akemi Shimada
Departments of Pharmacology, Orthodontics, Transcriptome Research Group, Department of Developmental Biology of Hard Tissue, Department of Molecular Pharmacology, School of Dental Medicine, Tsurumi University, 2‐1‐3 Tsurumi, Tsurumi‐ku, Yokohama 230-8501, Japan
Search for other papers by Akemi Shimada in
Google Scholar
PubMed
Search for other papers by Akemi Shimada in
Google Scholar
PubMed
Tatsuya Shibata
Tatsuya Shibata
Departments of Pharmacology, Orthodontics, Transcriptome Research Group, Department of Developmental Biology of Hard Tissue, Department of Molecular Pharmacology, School of Dental Medicine, Tsurumi University, 2‐1‐3 Tsurumi, Tsurumi‐ku, Yokohama 230-8501, Japan
Search for other papers by Tatsuya Shibata in
Google Scholar
PubMed
Search for other papers by Tatsuya Shibata in
Google Scholar
PubMed
Satoshi Wada
Satoshi Wada
Departments of Pharmacology, Orthodontics, Transcriptome Research Group, Department of Developmental Biology of Hard Tissue, Department of Molecular Pharmacology, School of Dental Medicine, Tsurumi University, 2‐1‐3 Tsurumi, Tsurumi‐ku, Yokohama 230-8501, Japan
Search for other papers by Satoshi Wada in
Google Scholar
PubMed
Search for other papers by Satoshi Wada in
Google Scholar
PubMed
Hisashi Ideno
Hisashi Ideno
Departments of Pharmacology, Orthodontics, Transcriptome Research Group, Department of Developmental Biology of Hard Tissue, Department of Molecular Pharmacology, School of Dental Medicine, Tsurumi University, 2‐1‐3 Tsurumi, Tsurumi‐ku, Yokohama 230-8501, Japan
Departments of Pharmacology, Orthodontics, Transcriptome Research Group, Department of Developmental Biology of Hard Tissue, Department of Molecular Pharmacology, School of Dental Medicine, Tsurumi University, 2‐1‐3 Tsurumi, Tsurumi‐ku, Yokohama 230-8501, Japan
Search for other papers by Hisashi Ideno in
Google Scholar
PubMed
Departments of Pharmacology, Orthodontics, Transcriptome Research Group, Department of Developmental Biology of Hard Tissue, Department of Molecular Pharmacology, School of Dental Medicine, Tsurumi University, 2‐1‐3 Tsurumi, Tsurumi‐ku, Yokohama 230-8501, Japan
Search for other papers by Hisashi Ideno in
Google Scholar
PubMed
Kazuhisa Nakashima
Kazuhisa Nakashima
Departments of Pharmacology, Orthodontics, Transcriptome Research Group, Department of Developmental Biology of Hard Tissue, Department of Molecular Pharmacology, School of Dental Medicine, Tsurumi University, 2‐1‐3 Tsurumi, Tsurumi‐ku, Yokohama 230-8501, Japan
Search for other papers by Kazuhisa Nakashima in
Google Scholar
PubMed
Search for other papers by Kazuhisa Nakashima in
Google Scholar
PubMed
Norio Amizuka
Norio Amizuka
Departments of Pharmacology, Orthodontics, Transcriptome Research Group, Department of Developmental Biology of Hard Tissue, Department of Molecular Pharmacology, School of Dental Medicine, Tsurumi University, 2‐1‐3 Tsurumi, Tsurumi‐ku, Yokohama 230-8501, Japan
Search for other papers by Norio Amizuka in
Google Scholar
PubMed
Search for other papers by Norio Amizuka in
Google Scholar
PubMed
Masaki Noda
Masaki Noda
Departments of Pharmacology, Orthodontics, Transcriptome Research Group, Department of Developmental Biology of Hard Tissue, Department of Molecular Pharmacology, School of Dental Medicine, Tsurumi University, 2‐1‐3 Tsurumi, Tsurumi‐ku, Yokohama 230-8501, Japan
Search for other papers by Masaki Noda in
Google Scholar
PubMed
Search for other papers by Masaki Noda in
Google Scholar
PubMed
Akira Nifuji
Akira Nifuji
Departments of Pharmacology, Orthodontics, Transcriptome Research Group, Department of Developmental Biology of Hard Tissue, Department of Molecular Pharmacology, School of Dental Medicine, Tsurumi University, 2‐1‐3 Tsurumi, Tsurumi‐ku, Yokohama 230-8501, Japan
Departments of Pharmacology, Orthodontics, Transcriptome Research Group, Department of Developmental Biology of Hard Tissue, Department of Molecular Pharmacology, School of Dental Medicine, Tsurumi University, 2‐1‐3 Tsurumi, Tsurumi‐ku, Yokohama 230-8501, Japan
Search for other papers by Akira Nifuji in
Google Scholar
PubMed
Departments of Pharmacology, Orthodontics, Transcriptome Research Group, Department of Developmental Biology of Hard Tissue, Department of Molecular Pharmacology, School of Dental Medicine, Tsurumi University, 2‐1‐3 Tsurumi, Tsurumi‐ku, Yokohama 230-8501, Japan
Search for other papers by Akira Nifuji in
Google Scholar
PubMed
replantation model To assess local effects of N-BPs on bone remodeling, a tooth replantation model ( Shibata et al . 2004 ) was used ( Supplementary Figure 1 , see section on supplementary data at the end of this article). Briefly, rat molars were extracted
