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Ashley Patton Department of Specialty Medicine, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, USA
Diabetes Institute, Ohio University, Athens, Ohio, USA
Department of Biological Sciences, Ohio University, Athens, Ohio, USA
Molecular & Cellular Biology Program, College of Arts and Sciences, Ohio University, Athens, Ohio, USA

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Tyler Church Department of Specialty Medicine, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, USA
Diabetes Institute, Ohio University, Athens, Ohio, USA

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Caroline Wilson Department of Chemical and Biomolecular Engineering, Russ College of Engineering and Technology, Ohio University, Athens, Ohio, USA

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Jean Thuma Department of Specialty Medicine, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, USA
Diabetes Institute, Ohio University, Athens, Ohio, USA

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Douglas J Goetz Department of Chemical and Biomolecular Engineering, Russ College of Engineering and Technology, Ohio University, Athens, Ohio, USA
Molecular & Cellular Biology Program, College of Arts and Sciences, Ohio University, Athens, Ohio, USA
Biomedical Engineering Program, Ohio University, Athens, Ohio, USA

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Darlene E Berryman Diabetes Institute, Ohio University, Athens, Ohio, USA
Department of Biomedical Sciences, Ohio University, Athens, Ohio, USA
The Edison Biotechnology Institute, Ohio University, Athens, Ohio, USA

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Edward O List Department of Specialty Medicine, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, USA
Diabetes Institute, Ohio University, Athens, Ohio, USA
The Edison Biotechnology Institute, Ohio University, Athens, Ohio, USA

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Frank Schwartz Department of Specialty Medicine, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, USA
Diabetes Institute, Ohio University, Athens, Ohio, USA

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Kelly D McCall Department of Specialty Medicine, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, USA
Diabetes Institute, Ohio University, Athens, Ohio, USA
Department of Biological Sciences, Ohio University, Athens, Ohio, USA
Molecular & Cellular Biology Program, College of Arts and Sciences, Ohio University, Athens, Ohio, USA
Biomedical Engineering Program, Ohio University, Athens, Ohio, USA
Department of Biomedical Sciences, Ohio University, Athens, Ohio, USA

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to the inflammation present in NAFLD ( Lu et al . 2008 , Broering et al . 2011 ). TLR4 signaling is mediated via two intracellular pathways involving the myeloid differentiation primary response 88 (MyD88) or adaptor proteins translocation

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M Giakoumopoulos Wisconsin National Primate Research Center, Obstetrics and Gynecology and, Comparative Biosciences, University of Wisconsin–Madison, 1223 Capitol Court, Madison, Wisconsin 53715-1299, USA
Wisconsin National Primate Research Center, Obstetrics and Gynecology and, Comparative Biosciences, University of Wisconsin–Madison, 1223 Capitol Court, Madison, Wisconsin 53715-1299, USA

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T G Golos Wisconsin National Primate Research Center, Obstetrics and Gynecology and, Comparative Biosciences, University of Wisconsin–Madison, 1223 Capitol Court, Madison, Wisconsin 53715-1299, USA
Wisconsin National Primate Research Center, Obstetrics and Gynecology and, Comparative Biosciences, University of Wisconsin–Madison, 1223 Capitol Court, Madison, Wisconsin 53715-1299, USA
Wisconsin National Primate Research Center, Obstetrics and Gynecology and, Comparative Biosciences, University of Wisconsin–Madison, 1223 Capitol Court, Madison, Wisconsin 53715-1299, USA

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cells can be derived from mouse embryos ( Silva & Smith 2008 , Ying et al . 2008 , Nichols & Smith 2009 ). Conversely, hESC require FGF2/ERK to self-renew and can be induced to differentiate by the canonical WNT/β-catenin signaling pathway ( Sumi et

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Jie Liu College of Veterinary Medicine, South China Agricultural University, Guangzhou, China
Department of Biology, Shantou University, Shantou, China

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Fei Gao Department of Biology, Shantou University, Shantou, China

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Yue-Fang Liu College of Veterinary Medicine, South China Agricultural University, Guangzhou, China

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Hai-Ting Dou College of Veterinary Medicine, South China Agricultural University, Guangzhou, China

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Jia-Qi Yan College of Veterinary Medicine, South China Agricultural University, Guangzhou, China

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Zong-Min Fan College of Veterinary Medicine, South China Agricultural University, Guangzhou, China

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Zeng-Ming Yang College of Veterinary Medicine, South China Agricultural University, Guangzhou, China

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, we showed that Prss56 expression during decidualization is regulated by HB-EGF/EGFR/ERK/Egr2 signaling pathway. Materials and methods Animals and treatment Mature CD1 mice used in this study were obtained from Hunan Slack Laboratory Animal

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Diego Crespo Reproductive Biology Group, Division Developmental Biology, Department Biology, Science Faculty, Utrecht University, Utrecht, The Netherlands

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Moline Severino Lemos Laboratory of Cell Biology, Department of Morphology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

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Yu Ting Zhang State Key Laboratory of Marine Environmental Science, College of Ocean and Earth Sciences, Xiamen University, Fujian, People’s Republic of China
Institute of Oceanography, Minjiang University, Fuzhou, People’s Republic of China

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Diego Safian Reproductive Biology Group, Division Developmental Biology, Department Biology, Science Faculty, Utrecht University, Utrecht, The Netherlands

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Birgitta Norberg Institute of Marine Research, Austevoll Research Station, Storebø, Norway

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Jan Bogerd Reproductive Biology Group, Division Developmental Biology, Department Biology, Science Faculty, Utrecht University, Utrecht, The Netherlands

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Rüdiger W Schulz Reproductive Biology Group, Division Developmental Biology, Department Biology, Science Faculty, Utrecht University, Utrecht, The Netherlands
Research Group Reproduction and Developmental Biology, Institute of Marine Research, Bergen, Norway

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regulatory protein CCTGGAATGCCTGAGCAGAA ATCTGCACTTGGTCGCATGAC ubc ubiquitin C CCATACACCGCACTCTTACAGAAA CCAGTCAGCGTCTTCACAAAGAT wnt5a wingless-type MMTV integration site family, member 5a TGGAGATCGTGGACGCAAA CACTTCAGGAATCAGCAGAGGATT

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Manuel D Gahete Maimonides Institute for Biomedical Research of Cordoba (IMIBIC), Córdoba, Spain
Department of Cell Biology, Physiology, and Immunology, Universidad de Córdoba, Córdoba, Spain
Reina Sofia University Hospital, Córdoba, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Córdoba, Spain
Agrifood Campus of International Excellence (ceiA3), Córdoba, Spain

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Juan M Jiménez-Vacas Maimonides Institute for Biomedical Research of Cordoba (IMIBIC), Córdoba, Spain
Department of Cell Biology, Physiology, and Immunology, Universidad de Córdoba, Córdoba, Spain
Reina Sofia University Hospital, Córdoba, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Córdoba, Spain
Agrifood Campus of International Excellence (ceiA3), Córdoba, Spain

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Emilia Alors-Pérez Maimonides Institute for Biomedical Research of Cordoba (IMIBIC), Córdoba, Spain
Department of Cell Biology, Physiology, and Immunology, Universidad de Córdoba, Córdoba, Spain
Reina Sofia University Hospital, Córdoba, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Córdoba, Spain
Agrifood Campus of International Excellence (ceiA3), Córdoba, Spain

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Vicente Herrero-Aguayo Maimonides Institute for Biomedical Research of Cordoba (IMIBIC), Córdoba, Spain
Department of Cell Biology, Physiology, and Immunology, Universidad de Córdoba, Córdoba, Spain
Reina Sofia University Hospital, Córdoba, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Córdoba, Spain
Agrifood Campus of International Excellence (ceiA3), Córdoba, Spain

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Antonio C Fuentes-Fayos Maimonides Institute for Biomedical Research of Cordoba (IMIBIC), Córdoba, Spain
Department of Cell Biology, Physiology, and Immunology, Universidad de Córdoba, Córdoba, Spain
Reina Sofia University Hospital, Córdoba, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Córdoba, Spain
Agrifood Campus of International Excellence (ceiA3), Córdoba, Spain

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Sergio Pedraza-Arévalo Maimonides Institute for Biomedical Research of Cordoba (IMIBIC), Córdoba, Spain
Department of Cell Biology, Physiology, and Immunology, Universidad de Córdoba, Córdoba, Spain
Reina Sofia University Hospital, Córdoba, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Córdoba, Spain
Agrifood Campus of International Excellence (ceiA3), Córdoba, Spain

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Justo P Castaño Maimonides Institute for Biomedical Research of Cordoba (IMIBIC), Córdoba, Spain
Department of Cell Biology, Physiology, and Immunology, Universidad de Córdoba, Córdoba, Spain
Reina Sofia University Hospital, Córdoba, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Córdoba, Spain
Agrifood Campus of International Excellence (ceiA3), Córdoba, Spain

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Raúl M Luque Maimonides Institute for Biomedical Research of Cordoba (IMIBIC), Córdoba, Spain
Department of Cell Biology, Physiology, and Immunology, Universidad de Córdoba, Córdoba, Spain
Reina Sofia University Hospital, Córdoba, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Córdoba, Spain
Agrifood Campus of International Excellence (ceiA3), Córdoba, Spain

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the development of ACTs, particularly in childhood ACTs, as 90% of cases display gains of 9q, which is the chromosomal region containing NR5A1 gene ( Figueiredo et al. 2005 ) The modulation of the classical WNT/β-catenin or associated pathways

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Yan Wang Department of Endocrinology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, China
Shandong Provincial Key Laboratory of Endocrinology and Lipid Metabolism, Jinan, Shandong Province, China
Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, China
Department of Endocrinology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong Province, China

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Mengqi Zhang Department of Endocrinology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, China
Shandong Provincial Key Laboratory of Endocrinology and Lipid Metabolism, Jinan, Shandong Province, China
Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, China
Department of Endocrinology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong Province, China

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Zhikun Huan Department of Endocrinology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, China
Shandong Provincial Key Laboratory of Endocrinology and Lipid Metabolism, Jinan, Shandong Province, China
Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, China
Department of Endocrinology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong Province, China

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Shanshan Shao Department of Endocrinology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, China
Shandong Provincial Key Laboratory of Endocrinology and Lipid Metabolism, Jinan, Shandong Province, China
Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, China
Department of Endocrinology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong Province, China

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Xiujuan Zhang Department of Endocrinology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, China
Shandong Provincial Key Laboratory of Endocrinology and Lipid Metabolism, Jinan, Shandong Province, China
Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, China
Department of Endocrinology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong Province, China

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Dehuan Kong Department of Endocrinology, Taian City Central Hospital, Taian, Shandong Province, China

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Jin Xu Department of Endocrinology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, China
Shandong Provincial Key Laboratory of Endocrinology and Lipid Metabolism, Jinan, Shandong Province, China
Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, China
Department of Endocrinology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong Province, China

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pathways, we measured the levels of the second messenger cyclic AMP (cAMP) by using an ELISA kit after FSH treatment. Forskolin is known to increase cAMP levels, so we used it as a positive control. The results showed that FSH inhibits cAMP production in

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Gina L C Yosten
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Grant R Kolar Department of Pharmacological and Physiological Science, Department of Pathology and Immunology, Saint Louis University School of Medicine, 1402 S Grand Boulevard, Saint Louis, Missouri 63104, USA

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Lauren J Redlinger
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Willis K Samson
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. ( doi:10.1016/S0092-8674(01)00483-4 ) Glinka A Dolde C Kirsch N Huang YL Kazanskaya O Ingelfinger D Boutros M Cruciat CM Niehrs C 2011 LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signaling . EMBO

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Cátia F Gonçalves Wellcome Centre for Cell Matrix Research, Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine & Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK

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Qing-Jun Meng Wellcome Centre for Cell Matrix Research, Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine & Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK

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differentiation of bone stromal cells into adipocytes and supressed osteogenic signalling pathways such as BMP, TGF-β and WNT, as well as osteoblast-specific transcription factors (e.g. Runx2 , Sox9 , and Sp7 ) ( Shockley et al. 2009 ). In vivo silencing of

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Anna de Lloyd Department of Child Health, Centre for Endocrine and Diabetes Sciences

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James Bursell Department of Child Health, Centre for Endocrine and Diabetes Sciences

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John W Gregory Department of Child Health, Centre for Endocrine and Diabetes Sciences

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D Aled Rees Department of Child Health, Centre for Endocrine and Diabetes Sciences

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Marian Ludgate Department of Child Health, Centre for Endocrine and Diabetes Sciences

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of the TSHR leads to over activation of the cAMP pathway that in turn causes thyroid hyperplasia and hyperthyroidism. This process occurs in Graves' disease (GD), the commonest cause of hyperthyroidism in which thyroid stimulating antibodies (TSAB

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Gen Chen School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, China

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Xiangjuan Chen Department of Obstetrics and Gynecology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China

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Chao Niu The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China

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Xiaozhong Huang The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China

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Ning An School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, China

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Jia Sun School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, China

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Shuai Huang School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, China

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Weijian Ye The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China

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Santie Li School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, China

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Yingjie Shen School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, China

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Jiaojiao Liang School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, China

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Weitao Cong School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, China

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Litai Jin School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, China

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-activated receptor gamma and the canonical WNT/β-Catenin pathway in chronic inflammation and oxidative stress during carcinogenesis . Frontiers in Immunology 9 745 . ( https://doi.org/10.3389/fimmu.2018.00745 ) 10.3389/fimmu.2018.00745 29706964 Waisundara VY

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