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R C M Simmen, J M P Pabona, M C Velarde, C Simmons, O Rahal, and F A Simmen

respective steroid signaling cascades ( Lydon et al . 1995 , Curtis et al . 2000 , Mulac-Jericevic et al . 2003 , Spears & Bartlett 2009 ). E 2 and progesterone actions are mediated by their cognate receptors, namely estrogen receptor (ESR) and

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Genevieve V Dall, Samuel Hawthorne, Yashar Seyed-Razavi, Jessica Vieusseux, Wanfu Wu, Jan-Ake Gustafsson, David Byrne, Leigh Murphy, Gail P Risbridger, and Kara L Britt

Estrogen receptor β exon 3-deleted mouse: the importance of non-ERE pathways in ERβ signaling . PNAS 112 5135 – 5140 . ( https://doi.org/10.1073/pnas.1504944112 ) 10.1073/pnas.1504944112 Masood S 1992 Estrogen and progesterone receptors in

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E Houdeau, A Lévy, and S Mhaouty-Kodja

) respectively) to increase intra-cellular concentrations of Ca 2+ . During pregnancy, these signalling pathways are silent due to the negative control exerted by progesterone. For instance, progesterone inhibits the expression of OTR and FP ( Larcher et

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Hélène Buteau-Lozano, Guillaume Velasco, Monique Cristofari, Patrick Balaguer, and Martine Perrot-Applanat

compounds, polychlorinated biphenyls (PCBs), polychlorinated dibenzodioxins, organochlorine pesticides, and bisphenol A (BPA), have been shown or suspected to disrupt endocrine functions in animals. Generally, endocrine disruptors have estrogenic activity

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Mi Ae Cho, Mi Kyung Lee, Kee-Hyun Nam, Woung Youn Chung, Cheong Soo Park, Ju Hyeong Lee, Taewoong Noh, Woo Ick Yang, Yumie Rhee, Sung-Kil Lim, Hyun Chul Lee, and Eun Jig Lee

-regulation of ER-beta in neoplastic tissues. Journal of Clinical Endocrinology and Metabolism 83 1025 –1028. Bur M , Shiraki W & Masood S 1993 Estrogen and progesterone receptor detection in neoplastic and non

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Hyun Joon Kim, Mary C Gieske, Kourtney L Trudgen, Susan Hudgins-Spivey, Beob Gyun Kim, Andree Krust, Pierre Chambon, Jae-Wook Jeong, Eric Blalock, and CheMyong Ko

special emphasis on studies in the ovine species . Archives of Physiology and Biochemistry 110 62 – 73 doi:10.1076/apab.110.1.62.898 . Clarke IJ Cummins JT 1984 Direct pituitary effects of estrogen and progesterone on gonadotropin secretion in

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Ana Gordon, José C Garrido-Gracia, Rafaela Aguilar, Carmina Bellido, Juan A García Velasco, Yolanda Millan, Manuel Tena-Sempere, Juana Martín de las Mulas, and José E Sánchez-Criado

P 1990 Two distinct estrogen-regulated promoters generate transcripts encoding the two fuctionally different human progesterone receptor forms A and B . EMBO Journal 9 1603 – 1614 . de Koning J 1995 Gonadotropin surge-inhibiting/attenuating factor

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Douglas A Gibson, Ioannis Simitsidellis, Frances Collins, and Philippa T K Saunders

Trukhacheva E Tokunaga H Utsunomiya H Yin P Luo X , et al . 2010 Estrogen receptor-beta, estrogen receptor-alpha, and progesterone resistance in endometriosis . Seminars in Reproductive Medicine 28 36 – 43 . ( https://doi.org/10.1055/s-0029

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J M P Pabona, M C Velarde, Z Zeng, F A Simmen, and R C M Simmen

receptor isoforms A and B determine transcriptional activity of progesterone-responsive genes in endometrial epithelial cells . Journal of Biological Chemistry 278 2174 – 21482 . Zheng FF Wu RC Smith CL O'Malley BW 2005 Rapid estrogen

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Ruijin Shao, Emil Egecioglu, Birgitta Weijdegård, Karin Ljungström, Charlotte Ling, Julia Fernandez-Rodriguez, and Håkan Billig

& Trotter A 2003 Ontogenetic expression of estrogen and progesterone receptors in the mouse lung. Biology of the Neonate 84 59 –63. Bullock DW , Lamb DJ, Rider VC & Kima PE 1987 The rabbit progesterone receptor and