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. Circadian rhythms are maintained by a set of core clock genes that form transcription-translation feedback loops in which they not only regulate their own transcription but that of many clock-controlled genes. The CLOCK-BMAL1 heterodimer forms the positive
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. 2014 ). Therefore, it is important to control body weight in women throughout life. Melatonin (N-acetyl-5-methoxytryptamine) is a molecule secreted by the pineal gland in a circadian manner. In addition to regulating circadian rhythms, melatonin has a
Hubei Clinical Research Center for Prenatal Diagnosis and Birth Health, Wuhan, Hubei, China
Fujian Provincial Key Laboratory of Reproductive Health Research, School of Medicine, Xiamen University, Xiamen, Fujian, China
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Hubei Clinical Research Center for Prenatal Diagnosis and Birth Health, Wuhan, Hubei, China
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Reproductive Medical Center, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China
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Reproductive Medical Center, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China
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Hubei Clinical Research Center for Prenatal Diagnosis and Birth Health, Wuhan, Hubei, China
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circadian rhythm is a precisely tuned process. In the human uterus, downregulation of PER2 in the endometrium marks the transition from oscillatory to nonoscillatory stroma, synchronizing the preimplantation embryo and surrounding decidual cells for fetal
Institut National de la Santé et de la Recherche Médicale U676, Hôpital Robert-Debré, 48 Boulevard Sérurier, F-75019 Paris, France
Department of Physiology and Pharmacology L334, Oregon Health & Science University, 3181 Southwest Sam Jackson Park Road, Portland, Oregon 97201-3098, USA
Institut de Physiologie et Biologie Cellulaires, Centre National de la Recherche Scientifique-Unité Mixte de Recherche, 6187 Pôle Biologie Santé, 40 Avenue du Recteur Pineau, 86022 Poitiers, France
Mental Retardation Research Center, University of California, Neurosciences Research Building, 655 Charles Young Drive South, Los Angeles, California 90095-7088, USA
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Institut National de la Santé et de la Recherche Médicale U676, Hôpital Robert-Debré, 48 Boulevard Sérurier, F-75019 Paris, France
Department of Physiology and Pharmacology L334, Oregon Health & Science University, 3181 Southwest Sam Jackson Park Road, Portland, Oregon 97201-3098, USA
Institut de Physiologie et Biologie Cellulaires, Centre National de la Recherche Scientifique-Unité Mixte de Recherche, 6187 Pôle Biologie Santé, 40 Avenue du Recteur Pineau, 86022 Poitiers, France
Mental Retardation Research Center, University of California, Neurosciences Research Building, 655 Charles Young Drive South, Los Angeles, California 90095-7088, USA
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Institut National de la Santé et de la Recherche Médicale U676, Hôpital Robert-Debré, 48 Boulevard Sérurier, F-75019 Paris, France
Department of Physiology and Pharmacology L334, Oregon Health & Science University, 3181 Southwest Sam Jackson Park Road, Portland, Oregon 97201-3098, USA
Institut de Physiologie et Biologie Cellulaires, Centre National de la Recherche Scientifique-Unité Mixte de Recherche, 6187 Pôle Biologie Santé, 40 Avenue du Recteur Pineau, 86022 Poitiers, France
Mental Retardation Research Center, University of California, Neurosciences Research Building, 655 Charles Young Drive South, Los Angeles, California 90095-7088, USA
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Institut National de la Santé et de la Recherche Médicale U676, Hôpital Robert-Debré, 48 Boulevard Sérurier, F-75019 Paris, France
Department of Physiology and Pharmacology L334, Oregon Health & Science University, 3181 Southwest Sam Jackson Park Road, Portland, Oregon 97201-3098, USA
Institut de Physiologie et Biologie Cellulaires, Centre National de la Recherche Scientifique-Unité Mixte de Recherche, 6187 Pôle Biologie Santé, 40 Avenue du Recteur Pineau, 86022 Poitiers, France
Mental Retardation Research Center, University of California, Neurosciences Research Building, 655 Charles Young Drive South, Los Angeles, California 90095-7088, USA
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Institut National de la Santé et de la Recherche Médicale U676, Hôpital Robert-Debré, 48 Boulevard Sérurier, F-75019 Paris, France
Department of Physiology and Pharmacology L334, Oregon Health & Science University, 3181 Southwest Sam Jackson Park Road, Portland, Oregon 97201-3098, USA
Institut de Physiologie et Biologie Cellulaires, Centre National de la Recherche Scientifique-Unité Mixte de Recherche, 6187 Pôle Biologie Santé, 40 Avenue du Recteur Pineau, 86022 Poitiers, France
Mental Retardation Research Center, University of California, Neurosciences Research Building, 655 Charles Young Drive South, Los Angeles, California 90095-7088, USA
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Institut National de la Santé et de la Recherche Médicale U676, Hôpital Robert-Debré, 48 Boulevard Sérurier, F-75019 Paris, France
Department of Physiology and Pharmacology L334, Oregon Health & Science University, 3181 Southwest Sam Jackson Park Road, Portland, Oregon 97201-3098, USA
Institut de Physiologie et Biologie Cellulaires, Centre National de la Recherche Scientifique-Unité Mixte de Recherche, 6187 Pôle Biologie Santé, 40 Avenue du Recteur Pineau, 86022 Poitiers, France
Mental Retardation Research Center, University of California, Neurosciences Research Building, 655 Charles Young Drive South, Los Angeles, California 90095-7088, USA
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demonstrated that the dark–light circadian rhythm is damaged in VIP null mice ( Colwell et al. 2003 ), suggesting that rhythmic secretion of gonadotropins might be perturbed in VIP KO mice. Altogether, these data strongly favor the idea that the lack of VIP
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cones ( Lucas & Foster 1999 ), indicating a role for the non-image-forming photoreceptor OPN4 in melatonin inhibition by light and circadian rhythms. The OPN4 photoreceptor is involved in both circadian re-setting mechanisms and pupillary light
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et al . 2015 ), at least partly via influencing adrenocortical ACTH sensitivity ( Oster et al . 2006 , Leliavski et al . 2014 ). How circadian rhythms affect the adaptive response to repeated and, importantly, predictable stressor exposure, though
Department of Cellular Physiology, Faculty of Science, UASLP, San Luis Potosí, México
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Department of Anatomy, Faculty of Medicine, UNAM, DF, México
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mimic their respective humoral circadian rhythms for an additional 4 weeks. Slow-release melatonin (Chronocaps; Productos Medix S.A. de C.V., México City, México) pill fragments equivalent to a concentration of 2.5 mg/kg and corticosterone (HBC complex
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HPG axis is dormant and ovulation does not occur, suggesting the shutdown of kisspeptin signaling, reduced GnRH neuron or gonadotrope sensitivity, or a combination of each. We therefore speculate that disruption of normal hypothalamic circadian rhythms
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preoptic area (POA; de la Iglesia et al . 1995 ). Transmission of the time-of-day signal from the SCN to CRH- and GnRH-synthesizing neurons is thought to be involved in the entrainment of the circadian rhythm governing the activities of the HPA and HPO
Lifelong Health Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia
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Lifelong Health Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia
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involved in circadian rhythm in liver, but with a phase delay in TRFd In ad libitum fed mice, HFD did not alter the amplitude (all P ≥ 0.11), mean (all P ≥ 0.38) or phase (all P ≥ 0.06) of any of the circadian regulators vs chow ( Fig. 4A , B