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London Regional Cancer Program, Biochemistry, 790 Commissioners Road, Room A4-921, London, Ontario, N6A 4L6 Canada Departments of
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London Regional Cancer Program, Biochemistry, 790 Commissioners Road, Room A4-921, London, Ontario, N6A 4L6 Canada Departments of
London Regional Cancer Program, Biochemistry, 790 Commissioners Road, Room A4-921, London, Ontario, N6A 4L6 Canada Departments of
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hormonal treatment, they were washed twice with 1× PBS and cultured in an oestrogen-depleted medium: phenol red-free DMEM-F12 medium with 10% charcoal-stripped FBS (Wisent) and 50 μg/ml penicillin–streptomycin, for 24 h. For gene regulation studies in MCF-7
Nottingham Digestive Disease Centre and Biomedical Research Centre, School of Medicine, University of Nottingham, Nottingham, UK
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et al . 2018 ). Dynamic changes in gene regulation with age are rarely examined but do enable the identification of important regulatory relationships. These will have crucial depot-specific roles to enable differentiation and the adaptation necessary
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Department of Gynecology, Key Research Laboratory of Gynecology, Guangzhou University of Traditional Chinese Medicine, Guangzhou, Guangdong, China
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412 179 – 190 . ( https://doi.org/10.1042/BJ20080281 ) 10.1042/BJ20080281 Iype T Francis J Garmey JC Schisler JC Nesher R Weir GC Becker TC Newgard CB Griffen SC Mirmira RG 2005 Mechanism of insulin gene regulation by the
Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy
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Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy
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Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy
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Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy
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activity) and that results in a male and female differential endocrine susceptibility and gene regulation, particularly in sex steroid-responsive genes. The relevance of oestrogen programming mechanisms within the mammalian foetus and perinatal time period
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DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Lübeck, Germany
CBBM (Center of Brain, Behavior and Metabolism), Lübeck, Germany
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FM Johren O Raasch W 2012 Improved insulin sensitivity after long-term treatment with AT1 blockers is not associated with PPARgamma target gene regulation . Endocrinology 153 1103 – 1115 . ( https://doi.org/10.1210/en.2011-0183 ) 22253423 10
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.09.001 ) 28969926 10.1016/j.tins.2017.09.001 Mitchner NA Garlick C Ben Jonathan N 1998 Cellular distribution and gene regulation of estrogen receptors alpha and beta in the rat pituitary gland . Endocrinology 139 3976 – 3983 . ( https://doi.org/10
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signaling . Endocrinology 154 4293 – 4304 . ( https://doi.org/10.1210/en.2013-1172 ) 24008343 10.1210/en.2013-1172 Mitchner NA Garlick C Ben-Jonathan N 1998 Cellular distribution and gene regulation of estrogen receptors alpha and beta in the rat
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of heart development and disease by glucocorticoids. DNA methylation DNA methylation catalyzed by DNA methyltransferases is an epigenetic mechanism for gene regulation ( Yang et al. 2010 ). Dynamic DNA methylation is vital for mammalian heart
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Biomolecular Science Institute, Florida International University, Miami, Florida, USA
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177 1947 – 1951 . ( https://doi.org/10.1016/j.juro.2007.01.002 ) Feng S Bogatcheva NV Truong A Korchin B Bishop CE Klonisch T Agoulnik IU Agoulnik AI 2007 Developmental expression and gene regulation of insulin-like 3 receptor
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Department of Physiology, College of Medicine, National Cheng Kung University, Tainan, Taiwan
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of gene regulation. It would be interesting to investigate whether hypoxia also regulates RNA or histone modification to modulate gene expression epigenetically in endometriosis. Figure 3 Hypoxia is involved in pathological processes of