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receptor isoforms A and B determine transcriptional activity of progesterone-responsive genes in endometrial epithelial cells . Journal of Biological Chemistry 278 2174 – 21482 . Zheng FF Wu RC Smith CL O'Malley BW 2005 Rapid estrogen
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metabolic profile seen in the liver, 4-hydroxylation is a dominant pathway of catechol estrogen formation in several extrahepatic tissues in both animal models and humans. Selective 4-hydroxylation of E 2 , with little or no 2-hydroxylation activity, has
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timing issue, and will assess the anti-atherosclerotic effects of conjugated equine estrogens alone and in combination with progesterone transdermally administrated in recently postmenopausal women ( Harman et al . 2005 ). These studies should explain
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oestrogens, whereas, in the absence of the cognate ligand, it induces progesterone receptor (PR) expression ( Bellido et al. 2003 ) and GnRH self-priming ( Sánchez-Criado et al. 2002 , Bellido et al. 2003 ). The mechanism through which these selective
Department of Neurosurgery, Farber Institute for Neurosciences, Thomas Jefferson University, 900 Walnut Street, Suite 400, Philadelphia, Pennsylvania 19107, USA
Department of Biology, Washington and Lee University, Lexington, Virginia 24450-03, USA
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Department of Neurosurgery, Farber Institute for Neurosciences, Thomas Jefferson University, 900 Walnut Street, Suite 400, Philadelphia, Pennsylvania 19107, USA
Department of Biology, Washington and Lee University, Lexington, Virginia 24450-03, USA
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Department of Neurosurgery, Farber Institute for Neurosciences, Thomas Jefferson University, 900 Walnut Street, Suite 400, Philadelphia, Pennsylvania 19107, USA
Department of Biology, Washington and Lee University, Lexington, Virginia 24450-03, USA
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Department of Neurosurgery, Farber Institute for Neurosciences, Thomas Jefferson University, 900 Walnut Street, Suite 400, Philadelphia, Pennsylvania 19107, USA
Department of Biology, Washington and Lee University, Lexington, Virginia 24450-03, USA
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Department of Neurosurgery, Farber Institute for Neurosciences, Thomas Jefferson University, 900 Walnut Street, Suite 400, Philadelphia, Pennsylvania 19107, USA
Department of Biology, Washington and Lee University, Lexington, Virginia 24450-03, USA
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Department of Neurosurgery, Farber Institute for Neurosciences, Thomas Jefferson University, 900 Walnut Street, Suite 400, Philadelphia, Pennsylvania 19107, USA
Department of Biology, Washington and Lee University, Lexington, Virginia 24450-03, USA
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, Simonian SX, van der Beek EM, Bicknell RJ & Herbison AE 1999 Fluctuating estrogen and progesterone receptor expression in brainstem norepinephrine neurons through the rat estrous cycle. Endocrinology 140 3255 –3263. Heritage
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Background The incidence of cardiovascular disease among women is low before menopause and steadily increases after the onset of menopause ( Mendelsohn & Karas 1999 ). This increase is believed to result in part from the loss of endogenous estrogen
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Laboratory of Tumor and Development Biology, INSERM-UMRS 938, Gynaecological Endocrinology Unit, GIGA-Cancer, Institute of Pathology, University of Liège, CHU-B23, B-4000 Liège, Belgium
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Tuohimaa P Ylikomi T 2002 Expression of progesterone receptor isoforms A and B is differentially regulated by estrogen in different breast cancer cell lines . Journal of Steroid Biochemistry and Molecular Biology 80 307 – 313 . ( doi:10.1016/S
Station de Recherches Avicoles, Institut National de la Recherche Agronomique, 37380 Nouzilly, France
INSERM UMR S671, Centre Biomédical des Cordeliers, Université Pierre et Marie Curie-Paris 6, Paris F-75006, France
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Station de Recherches Avicoles, Institut National de la Recherche Agronomique, 37380 Nouzilly, France
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Station de Recherches Avicoles, Institut National de la Recherche Agronomique, 37380 Nouzilly, France
INSERM UMR S671, Centre Biomédical des Cordeliers, Université Pierre et Marie Curie-Paris 6, Paris F-75006, France
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Station de Recherches Avicoles, Institut National de la Recherche Agronomique, 37380 Nouzilly, France
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Station de Recherches Avicoles, Institut National de la Recherche Agronomique, 37380 Nouzilly, France
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Station de Recherches Avicoles, Institut National de la Recherche Agronomique, 37380 Nouzilly, France
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& Hertelendy 1985 ). In the hen layerovary, as in mammals, theca and granulosa cells can be easily isolated from developing follicles. The granulosa cells from the largest follicles produce large amounts of progesterone, but unlike the mammalian granulosa cells
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of OT mRNA in the magnocellular neurones of the PVN ( Van Tol et al . 1988 ) increases at the onset of puberty and decreases after castration ( Miller et al . 1989 ), suggesting a possible influence of estrogen on OT expression levels. The
Group on Hormones and Signal Transduction, German Cancer Research Center, Heidelberg D-69120, Germany
Laboratory of Genomic Applications, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel
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Group on Hormones and Signal Transduction, German Cancer Research Center, Heidelberg D-69120, Germany
Laboratory of Genomic Applications, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel
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Group on Hormones and Signal Transduction, German Cancer Research Center, Heidelberg D-69120, Germany
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Group on Hormones and Signal Transduction, German Cancer Research Center, Heidelberg D-69120, Germany
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Group on Hormones and Signal Transduction, German Cancer Research Center, Heidelberg D-69120, Germany
Laboratory of Genomic Applications, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel
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Group on Hormones and Signal Transduction, German Cancer Research Center, Heidelberg D-69120, Germany
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Group on Hormones and Signal Transduction, German Cancer Research Center, Heidelberg D-69120, Germany
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indicating that the biological activity of the IGF system is strongly associated with estrogen status ( Lee et al. 1999 , Yee & Lee 2000 ). Estrogens were shown to increase IGF-I binding and IGF-IR mRNA levels in MCF-7 cells by sevenfold, suggesting that